GRUB_CMDLINE_LINUX_DEFAULT="quiet splash slab_nomerge psi=0 audit=0 nosoftlockup mce=ignore_ce intel_pstate=disable hugepagesz=1G hugepages=1 default_hugepagesz=1G amdgpu.ppfeaturemask=0xffffffff amdgpu.dcfeaturemask=2 mitigations=off"


I wouldn't copy and paste all of them, maybe look up each one and see what they do. The above works well for my use-case and machine.

For full tickless kernels, you can isolate CPUs and eliminate the tick and rcu (read, copy, update) callbacks:

isolcpus=1-3 nohz_full=1-3 rcu_nocbs=1-3

The above is for a 4-core, 0,1,2,3 are the different cores