foxposter

Treatments/Prophylactics

Jul 16th, 2020
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  1. CAUTION: All of this is advice from non-professionals with no formal training on dosages, side effects, or other complications. We do not know about your specific medical circumstances, such as other medications you may be on or preexisting conditions. Be careful, do your own research, consult doctors first, and keep this in mind if following the advice here
  2.  
  3. >PROPHYLAXIS
  4. Things to do before becoming infected, to reduce risk of infection or improve potential outcome
  5.  
  6. >proven/most critical/easiest
  7. Water: Consume ~3 liters of water a day. This should be done as part of a healthy lifestyle, pandemic or not. Water is critical for immune and body function
  8.  
  9. Sleep: 8 hours of sleep is recommended. Again, this is just important overall, and too little sleep will impair immune function
  10.  
  11. Zinc: Found in highest concentrations in oysters and beef as well as in other seafoods and meats, extremely important to immune function relating to coronavirus. Recommended dosage is 15mg a day, do not exceed 40mg or you may suffer from side effects including low copper levels
  12.  
  13. Lactoferrin: Binds to receptors on the cell wall that coronavirus uses to bring itself in, reducing chance of infection. Also is an anti-inflammatory. Found in cheeses and HTST-pasteurized milk, as well as supplements. Doesn't seem possible to overdose on cheese, supplements may cause runny stool if too much is taken
  14.  
  15. Vitamin D: High levels of vitamin D have been found to correlate with better survival rates with coronavirus. Sun exposure for 30-60 minutes a day is recommended, or D3 supplements. Do not exceed 4000 IU, and reduce dosage if any side effects occur
  16.  
  17. Vitamin C: Important for immune function and may be protective in the respiratory tract against coronaviruses. Recommended daily intake is ~100mg, but doses up to 2000 are considered relatively safe and without side effects. Good dietary sources are citrus fruit, peppers, and other fruits. Vitamin C is unlikely to be dangerous in doses larger than 2000mg a day, but may cause diarrhea or possibly kidney stones if sustained for a long period.
  18.  
  19. >secondary prophylaxis
  20. Magnesium: May promote vitamin D functions in protecting the respiratory epithelium and also act to control blood pressure and improve overall health. Can be found in leafy greens, nuts, whole grains, as well as in fortified breakfast cereals. Daily recommended value is ~400mg for men, ~300 for women, if you take supplements they may cause diarrhrea if taken in excess. Generally, avoid exceeding 300mg a day in supplements
  21.  
  22. Potassium: Potassium deficiency has been associated with some cases of coronavirus, and sufficient levels of it are important to overall health. Salmon, bananas, milk, and potatoes are all good sources of it. Daily recommended dose is ~3500mg, with an upper safe limit of ~5000mg depending on intake method
  23.  
  24.  
  25. >Unproven/fringe benefits
  26. Vitamin E: May prevent clotting associated with coronavirus, as well as being associated with vasodilation and reducing inflammation. Recommended daily allowance is ~15mg, can be found in high quantities in oils, peanut butter, and nuts. High doses may interfere with the body's ability to clot blood at wounds, do not exceed ~200mg for a sustained period
  27.  
  28. Nicotine/smoking: While smokers appear to have a significantly lower rate of contracting coronavirus, it is unknown whether this is due to smoking, the effects of nicotine on the body, or some other factor
  29.  
  30. Vitamin K2: Helpful for improving vitamin D absorption and heart/kidney health, found in cheeses and meats especially, so supplementation may be unnecessary. May cause increased blood clotting, which may worsen the effects of coronavirus, so additional supplements like vitamin pills is discouraged during infection
  31.  
  32. Quercetin: Has been associated in one study with antiviral activity, but may not have any significant effect in the body or make it far enough into the lungs to have an effect. Can be gotten in supplement form or found in fruits, citrus fruit, and onions. Bromelain from pineapples improves absorption.
  33.  
  34.  
  35. >related sources
  36.  
  37. >Water: you need it
  38.  
  39. >sleep: " "
  40.  
  41. >zinc:
  42. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247509/
  43.  
  44. >Lactoferrin
  45. -https://www.frontiersin.org/articles/10.3389/fimmu.2020.01221/full
  46. -https://clinicaltrials.gov/ct2/show/NCT04421534
  47. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271924/
  48.  
  49. >Vitamin D
  50. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276229/
  51.  
  52. >vitamin C
  53. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110025/
  54. -https://pubmed.ncbi.nlm.nih.gov/9306475/
  55.  
  56. >Magnesium
  57. -https://www.medrxiv.org/content/10.1101/2020.06.01.20112334v2
  58.  
  59. >Potassium
  60. -https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2767008
  61. -https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa.2016.4592
  62.  
  63. >Vitamin E
  64. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161532/
  65.  
  66. >Vitamin K
  67. -https://www.preprints.org/manuscript/202004.0457/v1
  68.  
  69. >Quercetin
  70. -https://www.frontiersin.org/articles/10.3389/fimmu.2020.01451/full
  71.  
  72.  
  73. >If infected
  74.  
  75.  
  76. Continue taking vitamin C or consuming foods rich in it, as well as supplementing zinc
  77.  
  78. >OTC treatments
  79.  
  80. Aspirin: May inhibit viral replication, thins blood to prevent clots, and may reduce inflamation. In clinical trials. Should not be taken by anyone under 18 due to risk of Reye's Syndrome
  81. -https://clinicaltrials.gov/ct2/show/NCT04365309
  82.  
  83. Bismuth subsalicylate(Pepto-bismol): May alleviate coronavirus-related diarrhea and possibly help with other symptoms. Do not nake with aspirin, as you run the risk of salicylate overdose
  84. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7159583/
  85. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302082/
  86.  
  87. Famotidine(Pepcid): Associated with reduced risk of death possibly by reducing inflammation by lowering histamine levels. 20-40mg doses are generally well tolerated, though 10mg may be sufficient. Can be taken before infection or symptoms if desired. Take before sleep
  88. -https://gut.bmj.com/content/early/2020/06/10/gutjnl-2020-321852
  89. -https://www.researchsquare.com/article/rs-30934/v2
  90.  
  91. Naxproxen(Aleve): An anti-inflammatory, it may also have anti-viral properties
  92. -https://clinicaltrials.gov/ct2/show/NCT04325633
  93. -https://www.biorxiv.org/content/10.1101/2020.04.30.069922v1.full.pdf
  94. -https://www.researchsquare.com/article/rs-21833/v1
  95.  
  96. >Prescription treatments
  97.  
  98. Azithromycin: Antibiotic, used to treat secondary infections by bacteria. Supposed by some to have other properties, unproven. Seems to be prescribed less now
  99. -https://www.cebm.net/covid-19/what-is-the-evidence-for-use-of-macrolide-antobiotics-for-treatmetnof-covid-19/
  100. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290142/
  101.  
  102. Colchicine: Being investigated as an anti-inflammatory
  103. -https://clinicaltrials.gov/ct2/show/NCT04322682
  104. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599469/
  105.  
  106. Contraindications:
  107.  
  108. Dextromethorphan(robitussin)-increases viral replication
  109. -https://www.nature.com/articles/s41586-020-2286-9
  110.  
  111. Adrafinil/modafinil-releases histamine, which may worsen coronavirus inflammation
  112. -https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/
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  121.  
  122. Much thanks to anons in /cvg/ and the anonymous author of
  123. >https://pastebin.com/raw/3MMpRP54
  124. for breaking the initial ground of this
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