input.txt

...text... <!-- 140101002 --> ...text...
...text... <!-- 140101030 --> ...text...
...text... <!-- 140101004 --> ...text...
...text... <!-- 140101058 --> ...text...

...text... <!-- name44 --> ...text...
...text... <!-- name2 --> ...text...
...text... <!-- name3 --> ...text...
...text... <!-- name94 --> ...text...

fhand = open("/home/Documents/input.txt")
template = open("/home/Documents/template.txt")
fout = open("/home/Documents/output.txt","w")

# store the values in the dictionary:
templateDict = dict()
for line in template:
  lineList = line.split("t")
  templateDict[lineList[0]] = lineList[1]

# replacement:
for line in fhand:
  for key in templateDict:
    if key in line2:
      line2 = line2.replace(key,templateDict[key])
  fout.write(line2) # write to output.txt

fout.close()

import re
d = dict(re.split('s+', i.strip('n')) for i in open('filename.txt'))
content = [i.strip('n') for i in open('filename2.txt')]
with open('results.txt', 'w') as f:
  f.write('n'.join(re.sub('(?<=<!--s)d+(?=s-->)', lambda x:d[x.group()], i) for i in content))

...text... <!-- name44 --> ...text...
...text... <!-- name2 --> ...text...
...text... <!-- name3 --> ...text...
...text... <!-- name94 --> ...text...