documentclass{article}

usepackage{blindtext}

usepackage{fontspec}
defaultfontfeatures{Path={/Users/you/.local/share/polytextum/fonts/}}
setmainfont[
  UprightFont=*-Regular,
  ItalicFont=*-Italic,
  BoldFont=*-Smbd,
  BoldItalicFont=*-SmbdItalic,
]{ArnoPro}

begin{document}
blinddocument
end{document}

documentclass{article}

usepackage{blindtext}

usepackage{fontspec}
defaultfontfeatures{Path={/Users/you/.local/share/polytextum/fonts/}}
setmainfont[
  UprightFeatures={
    SizeFeatures={
      {Size={-8.4},     Font=ArnoPro-Caption},
      {Size={8.5-10.9}, Font=ArnoPro-SmText},
      {Size={11-13.9},  Font=ArnoPro-Regular},
      {Size={14-21.4},  Font=ArnoPro-Subhead},
      {Size={21.5-},    Font=ArnoPro-Display}
    },
  },
  ItalicFeatures={
    SizeFeatures={
      {Size={-8.4},     Font=ArnoPro-ItalicCaption},
      {Size={8.5-10.9}, Font=ArnoPro-ItalicSmText},
      {Size={11-13.9},  Font=ArnoPro-Italic},
      {Size={14-21.4},  Font=ArnoPro-ItalicSubhead},
      {Size={21.5-},    Font=ArnoPro-ItalicDisplay}
    },
  },
  BoldFeatures={
    SizeFeatures={
      {Size={-8.4},     Font=ArnoPro-SmbdCaption},
      {Size={8.5-10.9}, Font=ArnoPro-SmbdSmText},
      {Size={11-13.9},  Font=ArnoPro-Smbd},
      {Size={14-21.4},  Font=ArnoPro-SmbdSubhead},
      {Size={21.5-},    Font=ArnoPro-SmbdDisplay}
    },
  },
  BoldItalicFeatures={
    SizeFeatures={
      {Size={-8.4},     Font=ArnoPro-SmbdItalicCaption},
      {Size={8.5-10.9}, Font=ArnoPro-SmbdItalicSmText},
      {Size={11-13.9},  Font=ArnoPro-SmbdItalic},
      {Size={14-21.4},  Font=ArnoPro-SmbdItalicSubhead},
      {Size={21.5-},    Font=ArnoPro-SmbdItalicDisplay}
    },
  }
]{ArnoPro}

begin{document}
blinddocument
end{document}

luaotfload | db : Reload initiated (formats: otf,ttf,ttc); reason: "File not found: /Users/aramis/.local/share/polytextum/fonts/ArnoPro.".

!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
!
! fontspec error: "font-not-found"
!
! The font "ArnoPro" cannot be found.
!
! See the fontspec documentation for further information.
!
! For immediate help type H <return>.
!...............................................

l.45

?

luaotfload | db : Reload initiated (formats: otf,ttf,ttc); reason: "File not found: /Users/aramis/.local/share/polytextum/fonts/ArnoPro-Regular.".

!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
!
! fontspec error: "font-not-found"
!
! The font "--" cannot be found.
!
! See the fontspec documentation for further information.
!
! For immediate help type H <return>.
!...............................................

l.45

?