header_checks = regexp:/etc/postfix/header_checks

/^Subject:$/          REPLACE Subject: No Subject Line
  /^Subject: $/         REPLACE Subject: No Subject Line

127.0.0.1:10026 inet  n -       n       -       16      smtpd
    -o content_filter=
    -o receive_override_options=no_unknown_recipient_checks,no_header_body_checks
    -o smtpd_helo_restrictions=
    -o smtpd_client_restrictions=
    -o smtpd_sender_restrictions=
    -o smtpd_recipient_restrictions=permit_mynetworks,reject
    -o mynetworks_style=host
    -o smtpd_authorized_xforward_hosts=127.0.0.0/8

Subject: