openpy

#!/usr/bin/env python
# -*- coding: utf-8 -*-
#
from openpyxl import Workbook
libro = Workbook()

# grab the active worksheet
hoja = libro.active

# Data can be assigned directly to cells
hoja['A1'] = 42

# Rows can also be appended
hoja.append([1, 2, 3])

# Python types will automatically be converted
import datetime
hoja['A3'] = datetime.datetime.now()

# Save the file
libro.save("MUESTRA.xlsx")