mylisting.tex

\documentclass[12pt,a4paper]{article}
\usepackage{listings}
\usepackage{xcolor}
\usepackage[most]{tcolorbox}

\begin{document}
\lstset{%
  basicstyle=\scriptsize\ttfamily,%
  commentstyle=\color{purple},% Works :)
  morecomment=[l]{\#}%
}
\section{There is no zero here}
\begin{lstlisting}
script.txt
# hello
hello
\end{lstlisting}
\end{document}