import itertools

def n_flipped(in_list, n):
  for to_flip in itertools.combinations(range(len(in_list)), n):
    new_item = in_list[:]
    for flip_index in to_flip:
      # flip 0 to 1 or vice versa
      new_item[flip_index] = 1 - new_item[flip_index]
    yield new_item

# Usage:
all_flipped_variants = list(n_flipped([1, 0, 1], 2))