//Creo la conexión

static Connection connection = null;
Class.forName("com.mysql.jdbc.Driver");
connection =DriverManager.getConnection( "jdbc:mysql://midominio.org:3306/nombreDB", "usuario", "contraseña");

        JFileChooser chooser = new JFileChooser();
        FileFilter imageFilter = new FileNameExtensionFilter("Imágenes", ImageIO.getReaderFileSuffixes());
        chooser.setFileFilter(imageFilter);
        chooser.showOpenDialog(null);
        File file = chooser.getSelectedFile();
        if(file != null)
        {
            BufferedImage img;
            FileInputStream fis = null;
            try {
                img=ImageIO.read(file);

                Image img2 = img.getScaledInstance(50, 67, 50);

                ImageIcon icon=new ImageIcon(img2);

                fotoLb.setIcon(icon);

                fotoLb.revalidate();
                fotoLb.repaint();

                fis = new FileInputStream(file);

                String sentencia = "UPDATE persona SET FOTOGRAFIA = ? WHERE id_persona = ?";

                PreparedStatement pst;
                try {
                    pst = connection.prepareStatement(sentencia);
                    pst.setBinaryStream(1, fis, (int) file.length());
                    pst.setInt(2,idPersona);

                    pst.executeUpdate();
                    pst.close();

                } catch (SQLException | IOException ex) {

                }
            }