<?php

$db = new PDO('mysql:host=localhost;dbname=database', 'username', '*****');

$req = $db->prepare("INSERT INTO users
	(login, password, email, lastname)
	VALUES (:login, :password, :email, :lastname)");

$req->execute(array(
	"login" => $_POST['login'],
	"password" => $_POST['password'],
	"email" => $_POST['email'],
	"lastname" => $_POST['lastname']
));