public partial class tbl_employee
    {
        public string[] EmpDiseases { get; set; }
        public List<Checkdisease> Disease { get; set; }
    }
    public class Checkdisease
    {
        public int id { get; set; }
        public string Name { get; set; }
        public bool emp_Disease { get; set; }
    }

using (hrm_DB db = new hrm_DB())
                {
                    emp = db.tbl_employee.Where(m => m.emp_Id == id).FirstOrDefault<tbl_employee>();
                    string disease = emp.emp_Disease;
                    string[] diseases = disease.Split(new[] {","}, StringSplitOptions.None);

                    emp.Disease = CheckDisease(diseases);
                }