Const cdoSendUsingPickup = 1
Const cdoSendUsingPort = 2
Const cdoAnonymous = 0
' Use basic (clear-text) authentication.
Const cdoBasic = 1
' Use NTLM authentication
Const cdoNTLM = 2 'NTLM

Public Sub SendEmail()
    Dim imsg As Object
    Dim iconf As Object
    Dim flds As Object
    Dim schema As String

    Set imsg = CreateObject("CDO.Message")
    Set iconf = CreateObject("CDO.Configuration")
    Set flds = iconf.Fields

    ' send one copy with SMTP server (with autentication)
    schema = "http://schemas.microsoft.com/cdo/configuration/"
    flds.Item(schema & "sendusing") = cdoSendUsingPort
    flds.Item(schema & "smtpserver") = "mail.myserver.com"
    flds.Item(schema & "smtpserverport") = 25
    flds.Item(schema & "smtpauthenticate") = cdoBasic
    flds.Item(schema & "sendusername") = "[email protected]"
    flds.Item(schema & "sendpassword") = "password"
    flds.Item(schema & "smtpusessl") = False
    flds.Update

    With imsg
        .To = "[email protected]"
        .From = "[email protected]"
        .Subject = "Test Send"
        .HTMLBody = "Test"
        '.Sender = "Sender"
        '.Organization = "My Company"
        '.ReplyTo = "[email protected]"
        Set .Configuration = iconf
        .Send
    End With

    Set iconf = Nothing
    Set imsg = Nothing
    Set flds = Nothing
End Sub

sMailServer = "myISPsmtp" 'Not just any old smtp
sMailFromAddress = "me"
sMailToAddress = "me"

Set ObjMessage = CreateObject("CDO.Message")
sToAddress = sMailToAddress
sSubject = "Subject"
sBody = "MailBody"

ObjMessage.Subject = sSubject
ObjMessage.From = sMailFromAddress
ObjMessage.To = sToAddress
'ObjMessage.cc = sCCAddress
ObjMessage.TextBody = sBody
'ObjMessage.AddAttachment sMailAttachment
ObjMessage.Configuration.Fields.Item("http://schemas.microsoft.com/cdo/configuration/sendusing") = 2
ObjMessage.Configuration.Fields.Item("http://schemas.microsoft.com/cdo/configuration/smtpserver") = sMailServer
ObjMessage.Configuration.Fields.Item("http://schemas.microsoft.com/cdo/configuration/smtpserverport") = 25
ObjMessage.Configuration.Fields.Update
ObjMessage.send

Sub SMPTTest2()
Set emailObj = CreateObject("CDO.Message")

emailObj.From = "[email protected]"
emailObj.To = "[email protected]"
emailObj.Subject = "Test CDO"
emailObj.TextBody = "Test CDO"
'emailObj.AddAttachment "c:windowswin.ini"

Set emailConfig = emailObj.Configuration


emailConfig.Fields("http://schemas.microsoft.com/cdo/configuration/sendusing") = 2
emailConfig.Fields("http://schemas.microsoft.com/cdo/configuration/smtpauthenticate") = 1
emailConfig.Fields("http://schemas.microsoft.com/cdo/configuration/smtpserver") = "smtp.office365.com"
'Exclude the following line
'emailConfig.Fields("http://schemas.microsoft.com/cdo/configuration/smtpserverport") = 587
emailConfig.Fields("http://schemas.microsoft.com/cdo/configuration/smtpusessl") = True
emailConfig.Fields("http://schemas.microsoft.com/cdo/configuration/sendusername") = "[email protected]"
emailConfig.Fields("http://schemas.microsoft.com/cdo/configuration/sendpassword") = "mypassword"
emailConfig.Fields.Update

emailObj.Send

If Err.Number = 0 Then MsgBox "Done"
End Sub