Set<Set<Card>> possible = new HashSet<Set<Card>>();
Card[] cards = your hand

for (Card card1 : cards) {
    for (Card card2 : cards) {
        if (card1 != card2) {
            Set<Card> hand = new HashSet<Card>();
            for (Card card : cards) {
                if (!card.equals(card1) || !card.equals(card2)) {
                    hand.add(card);
                }
            }
            possible.add(temp); //this will only add it if it's different since it's a set
        }
    }
}