grid

#!/usr/bin/env python
# -*- coding: utf-8 -*-
# posicionamiento grid

import tkinter as tk
from tkinter import ttk

ventana = tk.Tk()
ventana.title("GRID")
ventana.config(width=400, height=300)

caja = ttk.Entry()
caja.grid(row=0, column=0)

boton = ttk.Button(text="HOLA SOY UN BOTON")
# fijo el boton
boton.grid(row=1, column=1, sticky="nesw", padx=49, pady=40)

label = ttk.Label(text="JAJA")
label.grid(row=2, column=2)

label = ttk.Label(text="HOLA")
label.grid(row=3, column=3)

ventana.columnconfigure(1,weight=1)
ventana.rowconfigure(1,weight=1)




ventana.mainloop()