==Recommended perks==
Unless noted, the perks below are considered in isolation.

===Weapon only===
;Generally always useful
* {{perk link|Precise}} is the single best raw damage-per-second (DPS) perk at rank 5. Rank 3 and higher are relatively easy to earn from [[precise components]] (which also provide Equilibrium). Rank 5 requires [[Armadyl components]].
* {{perk link|Equilibrium}} is the next best for DPS, and is easily gotten in combination with Precise 3.
* {{perk link|Aftershock}} is the stronger version of Crackling, but is only good for high level gear as how often it activates is based on existing DPS. It is also fairly expensive to get, with the only sources being [[Anima Core of Zaros]] gear and the [[Dragon Rider lance]].

;Situational
* {{Perk link|Caroming}} can be useful for some slayer tasks or other weak monsters.
* {{perk link|Flanking}} is useful for team-based bosses where one player is the "tank" so others can get around the side. Does nothing for single-player combat.
* {{perk link|Lunging}} is good boost to melee combat (or if the target cannot move), but rank 3 Lunging is still less of a DPS increase than Precise 3 or Equilibrium 2.
* {{perk link|Planted Feet}} is useful for a weapon switch, and the damage reduction does not apply when switched back (but the increased duration remains).

===Armour only===
;Generally always useful
* {{perk link|Devoted}} is a very effective damage negation perk when using protection/deflection prayers. Obviously, does not work when using Soul Split or against typeless damage. Easy (if expensive) to get in combination with Impatient.
* {{perk link|Enhanced devoted}} is Devoted improved by 50%, but cannot have any other perks in the gizmo. So, increased damage reduction for the loss of some damage.
* {{perk link|Absorbative}} is effectively a simple increase in damage reduction. Relatively easy to get in combination with Venomblood.
* {{perk link|Lucky}} is similar (but a little less at maximum ranks) to Absorbative in terms of effective damage reduction, but they can be used together.
* {{perk link|Crystal shield (perk)}} has the third highest calculated effective damage reduction of
these perks (after both Devoted variants), but it appears to have issues preventing it from working correctly.

;Situational
* {{perk link|Venomblood}} is useful for certain bosses (e.g. [[Araxxor]], [[Gregorovic]]), and is fairly easy to get in combination with other perks.
* Perks only useful with shields:
** {{perk link|Bulwark}} increases Debilitate's duration much more with a shield (due to the higher base duration). Best with a tier 90 shield.
** {{perk link|Turtling}} is best with [[Primeval equipment|primeval]]/[[Teralith equipment|teralith]]/[[tempest equipment]], as the net improvement without the passive effect (of cooldown resets) is nil.
** {{perk link|Brief Respite}} improves the overall healing of Rejuvenate, but reduces the healing of Guthix's Blessing.

===Weapons and/or armour===
Perks that can be on either weapons or armour should generally go on armour, as the weapon-exclusive perks are so good and there's limited space for them.

;Generally always useful
* {{perk link|Impatient}} is a very strong DPS and tanking perk, allowing faster adrenaline generation so thresholds and ultimates can be done more often.
* {{perk link|Crackling}} is a good perk that adds damage occasionally. It is not as strong as Aftershock, but they can both be used.
* {{perk link|Biting}} increases DPS slightly less than Equilibrium, but is still strong.
** Biting does not function with Equilibrium, so pick one.

;Situational
* {{perk link|Mobile}} is useful at several bosses where movement is important, and in general skilling for the increased movement speed. Commonly used on an off-hand weapon or shield while training.
* {{perk link|Undead Slayer}}, {{perk link|Dragon Slayer (perk)}}, and {{perk link|Demon Slayer (perk)}} are strong increases, but useful against specific monsters/bosses only.
* {{perk link|Genocidal}} is useful on slayer tasks only, and isn't as strong as higher ranked Precise or Equilibrium (but can be used with them).
* {{perk link|Trophy-taker's}} is a net increase in slayer task length, so good to extend how long the effects of the slayer helm are active for the monster. Easy to combo a middle rank with Genocidal.
* {{perk link|Shield Bashing}} is a fairly good increase to Debilitate's damage, but not as good as the weapon perks.

===Tools===
;Generally always useful
* {{Perk link|Honed}} is the best skilling perk, as the only one that increases the raw success rate.

;Situational
* {{perk link|Furnace (perk)}} is the highest increase in experience per hour, but it does consume the item produced when it activates. Use if you only care for the experience.
* {{perk link|Polishing}} can slightly improve gold per hour for some training methods, but this use is niche. It also improves chimes per hour if used in [[the Arc]].
* {{perk link|Refined}} is only really useful when mining single-ore rocks, but it noticeably improves them. Fishing and woodcutting don't really benefit from it.
* {{perk link|Charitable}} helps out others in group training, but minimal benefit to yourself unless others also use it. Ideally used with other players at places like [[harmonised runite rock]]s.
* {{perk link|Butterfingers}} is usually undesirable, but it can improve training methods where the product is dropped anyway (e.g. mining [[granite]]).

===All gizmos===
;Generally always useful
* {{perk link|Wise}} affects every skill, so is ideally used while skilling. Wise 2/Mobile is not uncommon to make and use on an off-hand weapon/shield.

;Situational
* {{perk link|Enlightened}} is useful for Invention training, but only applies on the item it is on.
* {{perk link|Efficient}} can help reduce Invention training costs, if a perk slot can be sacrificed for every item in use.
* {{perk link|Enhanced efficient}} is a 50% better Efficient that can't be comboed with anything.