$ sudo apt-get remove libpcre2-16-0 libpcre2-32-0 libpcre2-8-0  libpcre2-dev libpcre2-posix3
Reading package lists... Done
Building dependency tree
Reading state information... Done
Some packages could not be installed. This may mean that you have
requested an impossible situation or if you are using the unstable
distribution that some required packages have not yet been created
or been moved out of Incoming.
The following information may help to resolve the situation:

The following packages have unmet dependencies:
 crda : Depends: libssl1.1 (>= 1.1.0) but it is not going to be installed
 grub-pc : Depends: debconf (>= 0.5) but it is not going to be installed or
                    debconf-2.0
           Depends: grub-common (= 2.04-1ubuntu26.15) but it is not going to be installed
           Depends: grub2-common (= 2.04-1ubuntu26.15) but it is not going to be installed
           Depends: grub-pc-bin (= 2.04-1ubuntu26.15) but it is not going to be installed
           Depends: ucf but it is not going to be installed
           Depends: grub-gfxpayload-lists but it is not going to be installed
 initramfs-tools : Depends: initramfs-tools-core (= 0.136ubuntu6.7) but it is not going to be installed
 kmod : Depends: libssl1.1 (>= 1.1.0) but it is not going to be installed
        Depends: libkmod2 (= 27-1ubuntu2.1) but it is not going to be installed
 linux-base : Depends: debconf (>= 0.5) but it is not going to be installed or
                       debconf-2.0
 nginx-core : Depends: libnginx-mod-brotli (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: libnginx-mod-http-geoip (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: libnginx-mod-http-image-filter (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: libnginx-mod-http-xslt-filter (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: libnginx-mod-mail (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: libnginx-mod-stream (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: libnginx-mod-stream-geoip (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: libnginx-mod-ssl-ct (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: nginx-common (= 1.21.6-1+ubuntu20.04.1+deb.sury.org+2) but it is not going to be installed
              Depends: iproute2
              Depends: libssl1.1 (>= 1.1.1) but it is not going to be installed
E: Error, pkgProblemResolver::Resolve generated breaks, this may be caused by held packages.