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Ropivacaine Hydrochloride for Local Anesthetic

Feb 27th, 2018
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  9. Ropivacaine hydrochloride Description:
  10. Ropivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain. Ropivacaine is used as a local (in only one area) anesthesia for a spinal block, also called an epidural. The medication is used to provide anesthesia during a surgery or C-section, or to ease labor pains.Ropivacaine is a local anaesthetic drug belonging to the amino amide group. The name ropivacaine refers to both the racemate and the marketed S-enantiomer. Ropivacaine may also be used for purposes not listed in this medication guide. Ropivacaine is indicated for local anaesthesia including infiltration, nerve block, epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children.
  11. Ropivacaine is often coadministered for epidural analgesia, for example in pregnant women during labour.
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  13. Name: Ropivacaine hydrochloride
  14. CAS No.: 132112-35-7
  15. Appearance:White to white crystalls or crystal powder
  16. Formula: C17H29ClN2O2
  17. Molecular Weight: 328.88
  18. Synonyms: 2-Piperidinecarboxamide,N-(2,6-dimethylphenyl)-1-propyl-, monohydrochloride,monohydrate, (2S)- (9CI);2-Piperidinecarboxamide,N-(2,6-dimethylphenyl)-1-propyl-, monohydrochloride,monohydrate, (S)-;Ropivacaine hydrochloridemonohydrate;Ropivacaine HCL;(s)-n-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride;
  19. EINECS:
  20. Density:
  21. Melting Point: 267-269 °C
  22. Boiling Point: 410.2 °C at 760 mmHg
  23. Flash Point: 201.9 °C
  24. Solubility:
  25. Appearance: white solid
  26. Hazard Symbols: ToxicT
  27. Risk Codes: 26/27/28
  28. Safety: 22-36/37/39-45
  29. Surgical anesthesia, epidural anesthesia
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  31. Clinical use:
  32. Ropivacaine is indicated for local anaesthesia including infiltration, nerve block, epidural and intrathecal anaesthesia in adults and children over 12 years. It is also indicated for peripheral nerve block and caudal epidural in children 1-12 years for surgical pain. It is also sometimes used for infiltration anaesthesia for surgical pain in children.
  33. Ropivacaine is often coadministered for epidural analgesia, for example in pregnant women during labour.
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