list1 = [(1100, 'abc', '{"1209": "Y", "1210": "Y"}'), (1100, 'abc', None)]

def insert_sample_data(col_val):
    cur = self.con.cursor()
    sql = """insert into sampletable values {}""".format(col_val)
    cur.execute(sql)
    self.con.commit()
    cur.close()

values1 = ', '.join(map(str, list1))  #bulk insert
insert_sample_data(values1)