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Apr 3rd, 2020 (edited)
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  1. Удобный информативный FAQ пастбин на английском.
  2. https://pastebin.com/raw/jeDsZPGd
  3. -------------------------------------------------------------------------------------------
  4. Симптомы
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243791/
  6. -------------------------------------------------------------------------------------------
  7. ДЕСЯТЬ ГЛАВНЫХ НЕ ОТВЕЧЕННЫХ ВОПРОСОВ О SARS2
  8. The 2019 human coronavirus: Ten areas of uncertainty waiting to be resolved
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235473/
  10. http://archive.is/eCjTY
  11. -------------------------------------------------------------------------------------------
  12. ОТЧЕТ ВОЗ и КНР В КОТОРОМ ТРЕБУЮТ ПРИЗНАТЬ ВИРУС ОПАСНЫМ
  13. https://www.rosminzdrav.ru/news/2020/03/04/13469-predstavlen-otchet-o-rabote-mezhdunarodnoy-missii-voz-po-probleme-covid-19
  14. -------------------------------------------------------------------------------------------
  15. СПОСОБЫ ПЕРЕДАЧИ/AIRBORNE/AEROSOLIZATION/FOMITE
  16. Identifying airborne transmission as the dominant route for the spread of COVID-19
  17. https://www.pnas.org/content/early/2020/06/10/2009637117
  18.  
  19. Stability of SARS-CoV-2 in different environmental conditions
  20. https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(20)30003-3/fulltext#sec1
  21.  
  22. SARS2 and airborne transmissions*
  23. https://www.sciencedirect.com/science/article/pii/S2590252020300143
  24. http://archive.is/JsXmN
  25.  
  26. Evoporated SARS2 droplets on surfaces
  27. https://arxiv.org/abs/2005.12262
  28. http://archive.is/F5Mcy
  29.  
  30. Fomite transmissions of SARS2
  31. https://arxiv.org/abs/2005.11443
  32. http://archive.is/lexYG
  33.  
  34. Surface and air contamination of SARS2
  35. https://www.medrxiv.org/content/10.1101/2020.05.24.20110346v1
  36. http://archive.is/pCYen
  37.  
  38. SARS2 can travel up to 100 meters
  39. https://www.researchhub.com/paper/817121/summary
  40. http://archive.is/tv1JO
  41.  
  42. Particulate matter (PM2.5) as a potential SARS-CoV-2 carrier
  43. >Herein, we report the involvement of fine indoor air particulate with the diameter of ≤ 2.5 µm (PM2.5) as the transport agent of the virus. PM2.5 was collected over four weeks during a 48 hours measurement intervals in four separate wards containing different infected clusters in a teaching hospital in Kuala Lumpur, Malaysia. Our results indicated highest SARS-CoV-2 RNA on PM2.5 in the ward associated with a lavatory.
  44. https://www.researchsquare.com/article/rs-33354/v1
  45.  
  46. [b]Исследование продолжительности жизни вируса вне носителя(до 3х часов в воздухе, 24х часов на картоне и 2-3 дней на пластике и стали[/b]
  47. >We found that viable virus could be detected in aerosols up to 3 hours post aerosolization, up to 4 hours on copper, up to 24 hours on cardboard and up to 2-3 days on plastic and stainless steel
  48. https://www.medrxiv.org/content/10.1101/2020.03.09.20033217v1.full.pdf
  49.  
  50. Распространяется через фекалии и их запахи - твёрдо и четко
  51. https://wwwnc.cdc.gov/eid/article/26/8/20-0681_article
  52.  
  53. Risk of SARS-CoV-2 infection from contaminated water systems
  54. >We identify that the virus can remain stable within water for up to 25 days
  55. https://www.medrxiv.org/content/10.1101/2020.06.17.20133504v1
  56.  
  57. Лифт и бессимптомный носитель
  58. Large SARS-CoV-2 Outbreak Caused by Asymptomatic Traveler, China
  59. https://wwwnc.cdc.gov/eid/article/26/9/20-1798_article
  60. -------------------------------------------------------------------------------------------
  61. Мелотанин и разная эксперементальная терапия
  62.  
  63. Therapeutic Algorithm for Use of Melatonin in Patients With COVID-19
  64. https://www.frontiersin.org/articles/10.3389/fmed.2020.00226/full
  65. Melatonin is a dynamic immunological treatment*
  66. http://archive.is/qD8Ml
  67.  
  68. Zinc iodide as a treament for SARS2*
  69. https://www.sciencedirect.com/science/article/pii/S030698772030503X
  70. http://archive.is/6IeGp
  71.  
  72. Medications to increase/decrease ACE2 expression
  73. http://archive.is/V4bUp
  74. https://www.medrxiv.org/content/10.1101/2020.05.25.20100438v1
  75. -------------------------------------------------------------------------------------------
  76. Маски нужны:
  77. https://www.ncbi.nlm.nih.gov/pubmed/32064854
  78. https://jamanetwork.com/journals/jama/fullarticle/184819
  79. -------------------------------------------------------------------------------------------
  80. ВСЕ ПРИНИМАВШИЕ АРБИДОЛ УМЕРЛИ НАХУЙ, КЛИНИЧЕСКОЕ ИССЛЕДОВАНИЕ
  81. https://www.medrxiv.org/content/10.1101/2020.02.17.20024166v3.full.pdf
  82. -------------------------------------------------------------------------------------------
  83. Курильщики подвержены вирусу сильнее
  84. https://www.medrxiv.org/content/10.1101/2020.02.05.20020107v1
  85. -------------------------------------------------------------------------------------------
  86. Potential influence of Coronavirus/ACE2 on the female reproductive system
  87. https://academic.oup.com/molehr/advance-article/doi/10.1093/molehr/gaaa030/5828941
  88. У переболевших COVID-19 наблюдаются проблемы с почками и репродуктивной системой, как следствие - бесплодность
  89. https://www.medrxiv.org/content/10.1101/2020.02.12.20022418v1.full.pdf
  90. -------------------------------------------------------------------------------------------
  91. Индекс распространения между 6.11 и 8.18, выше чем ожидалось
  92. https://archive.is/1WTiA
  93. -------------------------------------------------------------------------------------------
  94. [b]Слитая презентация для госпиталей США по подготовке к эпидемии. 98 миллионов зараженных в США, 480к смертей:[/b]
  95. [b]http://archive.is/9wLaw[/b]
  96. Ссылка на PDF https://gofile.io/?c=NDDHhj
  97. -------------------------------------------------------------------------------------------
  98. COVID19 - Летающий спидорак, теперь оффициально.
  99. https://www.globaltimes.cn/content/1181121.shtml
  100. [b]Иммунная система идёт по пизде от covid19, воздушный СПИДОРАК официально[/b]
  101. https://www.nature.com/articles/s41423-020-0424-9
  102. -------------------------------------------------------------------------------------------
  103. COVID-19-associated invasive pulmonary aspergillosis
  104. https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-020-00686-4
  105. http://archive.is/zT5JF
  106. -------------------------------------------------------------------------------------------
  107. Животные
  108. Animal-to-human transmission confirmed
  109. https://www.biorxiv.org/content/10.1101/2020.05.18.101493v1
  110. http://archive.is/T85H3
  111. https://newsroom.wcs.org/News-Releases/articleType/ArticleView/articleId/14010/A-Tiger-at-Bronx-Zoo-Tests-Positive-for-COVID-19-The-Tiger-and-the-Zoos-Other-Cats-Are-Doing-Well-at-This-Time.aspx
  112. https://www.biorxiv.org/content/10.1101/2020.04.01.021196v1.full.pdf
  113.  
  114. Возможные рекомбинации в популяции животных
  115. Sewage of human waste is spreading the virus to wildlife near the treatment plants including bats, who can mix Coronachan with other coronavirus and then pass it back to humans more lethal than before. Beware sewage leaks near you.
  116. The study:
  117. https://www.sciencedirect.com/science/article/pii/S0048969720328758
  118. >This proposed model is premised on transmission of SARS-CoV-2 from human feces through municipal waste water treatment plants into the natural aquatic environment where potential wildlife hosts become infected.
  119. >Although we focus on North America, our conceptual model could apply to other parts of the globe as well.(remember Brazilian bat anon?)
  120. >We believe the existing evidence also supports the plausibility of novel coronaviruses, such as SARS-CoV-2, spilling over to new wildlife hosts through fecal shedding by infected humans and introduction to the natural aquatic environment via the waste water treatment system. Such scrutiny could integrate surveillance of key wildlife species, such as bats and raccoons, which have the potential for acquiring coronaviruses from their aquatic environments.
  121. Brace for recombination events
  122. >However, bats remain the most likely species where spillover of SARS-CoV-2 might occur. Bats drink directly from natural water sources, such as lakes, ponds and slow-flowing streams and rivers, by swooping over the water sources and lapping at the surface.
  123. >Of particular concern, is whether there is the potential for recombination of SARS-CoV-2 with other bat coronaviruses should spillover of SARS-CoV-2 occur in bat populations.
  124. -------------------------------------------------------------------------------------------
  125. [b]1 out of 4 SARS2 patients had kidney failure[/b]
  126. https://www.medrxiv.org/content/10.1101/2020.05.08.20096040v1
  127. Исследование с помощью уриноанализа показало что коронавирус может нанести урон почкам.
  128. https://www.medrxiv.org/content/10.1101/2020.04.03.20051722v1
  129. -------------------------------------------------------------------------------------------
  130. Pulmonary Thromboembolic Disease in Patients with COVID-19 Undergoing Computed Tomography Pulmonary Angiography (CTPA): Incidence and Relationship with Pulmonary Parenchymal Abnormalities
  131. >The concomitant presence of fibrotic features on CT indicates the need for follow-up for evaluation of CHRONIC pulmonary complications.
  132. https://www.medrxiv.org/content/10.1101/2020.06.01.20118505v1
  133. -------------------------------------------------------------------------------------------
  134. FDG PET/CT scan reveals hypoactive orbitofrontal cortex in anosmia of COVID-19
  135. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196385/
  136. -------------------------------------------------------------------------------------------
  137. Systemic Effects of Missense Mutations on SARS-CoV-2 Spike Glycoprotein Stability and Receptor Binding Affinity
  138. https://www.biorxiv.org/content/10.1101/2020.05.21.109835v1.full.pdf
  139. -------------------------------------------------------------------------------------------
  140. The MERS-CoV receptor DPP4 as a candidate binding target of the SARS-CoV-2 spike
  141. https://www.sciencedirect.com/science/article/pii/S258900422030345X
  142. -------------------------------------------------------------------------------------------
  143. ORF3c gene isolated and emerged with G614 mutation
  144. A previously uncharacterized gene in SARS-CoV-2 illuminates the functional dynamics and evolutionary origins of the COVID-19 pandemic
  145. https://www.biorxiv.org/content/10.1101/2020.05.21.109280v1
  146. -------------------------------------------------------------------------------------------
  147. An insertion unique to SARS-CoV-2 exhibits superantigenic character strengthened by recent mutations
  148. SARS2 "superantigen" insertion never seen in SARS CoV
  149. http://archive.is/G6fEO
  150. https://www.biorxiv.org/content/10.1101/2020.05.21.109272v1
  151. -------------------------------------------------------------------------------------------
  152. Overall, the data indicates that SARSCoV2 is uniquely adapted to infect humans, raising questions of its origin
  153. https://arxiv.org/abs/2005.06199
  154. -------------------------------------------------------------------------------------------
  155. Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
  156. https://www.biorxiv.org/content/10.1101/2020.06.17.157982v1
  157. -------------------------------------------------------------------------------------------
  158. Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
  159. https://www.nature.com/articles/s41577-020-0331-4
  160. -------------------------------------------------------------------------------------------
  161. SARS-CoV-2 strategically mimics proteolytic activation of human ENaC
  162. >spike protein’s furin cleavage site is identical to a sequence in the human epithelial sodium channel, which likewise must be cut by furin in order to be activated
  163. https://archive.is/PxPpi
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  165. Новый опасный штамм в Индии
  166. https://www.deccanchronicle.com/science/science/040620/ccmb-clalims-discovery-of-more-virulent-strain-of-covid-19-virus-in-in.html
  167.  
  168. https://www.biorxiv.org/content/10.1101/2020.05.31.126136v1
  169. ---------------------------------------------------------------------------------------------------------------------------
  170. Thrombotic Neurovascular Disease in COVID-19 Patients
  171. >Patients with signs of stroke were delaying coming to the hospital for fear of getting the coronavirus. There's a small window of time in which strokes are treatable, so delays can be life threatening.
  172.  
  173. >The mortality rate in covid-19 stroke patients is 42.8%. The typical mortality from stroke is around 5 to 10%.
  174.  
  175. >42% of the stroke coronavirus positive patients studied were under the age of 50. Most strokes, over 75% of all strokes in the US, occur in people over the age of 65.
  176.  
  177. >The incidence of coronavirus in the stroke population was 31.5%, according to this sample of patients.
  178.  
  179. >Patients observed had stroke in large vessels, in both hemispheres of the brain, and in both arteries and veins of the brain - all of these observations are unusual in stroke patients.
  180.  
  181. http://archive.is/FjWbJ
  182. ---------------------------------------------------------------------------------------------------------------------------
  183. Иммунитет? Нет.
  184. ---------------------------------------------------------------------------------------------------------------------------
  185. Реинфекции confirmed.
  186. COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing
  187. https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1275/5897019
  188. -------------------------------------------------------------------------------------------
  189. Coronavirus protective immunity is short-lasting
  190. https://www.medrxiv.org/content/10.1101/2020.05.11.20086439v2
  191. -------------------------------------------------------------------------------------------
  192. Spain's coronavirus antibodies study adds evidence against herd immunity
  193. https://edition.cnn.com/2020/07/06/health/spain-coronavirus-antibody-study-lancet-intl/index.html
  194.  
  195. >Spain's large-scale study on the coronavirus indicates just 5% of its population has developed antibodies, strengthening evidence that a so-called herd immunity to Covid-19 is "unachievable," the medical journal the Lancet reported on Monday.
  196. >The findings show that 95% of Spain's population remains susceptible to the virus. Herd immunity is achieved when enough of a population has become infected with a virus or bacteria -- or vaccinated against it -- to stop its circulation.
  197.  
  198. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31483-5/fulltext
  199. -------------------------------------------------------------------------------------------
  200. Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
  201.  
  202. https://www.biorxiv.org/content/10.1101/2020.07.13.190140v1
  203. -------------------------------------------------------------------------------------------
  204. ADE - antibody-dependent enhancement, - Антителозависимое усиление инфекции
  205.  
  206. Coronavirus vaccine developers wary of errant antibodies
  207. https://www.nature.com/articles/d41587-020-00016-w
  208.  
  209. Paradoxical dynamics of SARS-CoV-2 by herd immunity and ADE
  210. https://www.cambridge.org/engage/coe/article-details/5ead2b518d7bf7001951c5a5
  211.  
  212. Evidence for SARS2 ADE (peer reviewed)
  213. https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30702-6#%20
  214. http://archive.is/26p4J
  215.  
  216. Immunity after COVID-19: protection or sensitization ?
  217. https://www.medrxiv.org/content/10.1101/2020.05.21.20108860v1
  218.  
  219. Genomic ADE research
  220. https://www.cambridge.org/core/services/aop-cambridge-core/content/view/504FE38E2475590EFE93872BC6D67D3D/S2059866120000394a.pdf
  221.  
  222. Mistaken assumptions about SARS-CoV-2's aetiology risk creating ineffective or actively harmful vaccines, including the risk of Antibody-Dependent Enhancement (ADE). Such problems in vaccine design are illustrated from past experience in the HIV domain. We propose that the dual effect general method of action of this chimeric virus’s spike, including receptor binding domain, includes membrane components other than the ACE2 receptor, which explains clinical evidence of its infectivity and pathogenicity
  223.  
  224. https://www.cambridge.org/core/services/aop-cambridge-core/content/view/DBBC0FA6E3763B0067CAAD8F3363E527/S2633289220000083a.pdf/biovacc19_a_candidate_vaccine_for_covid19_sarscov2_developed_from_analysis_of_its_general_method_of_action_for_infectivity.pdf
  225. ----------------------------------------------------------
  226. Immune evasion via SARS-CoV-2 ORF8 protein
  227. The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I
  228.  
  229. Viral infection would elicit effective innate and adoptive immune response to inhibit the viral replication. Apparently, the anti-viral immunity on SARS-CoV-2 infection remains largely unknown. A proportion of recovered patients still exhibit as the virus carriers and the case of CD8+ lymphocytes dysfunction was reported
  230. These clinical characters of COVID-19 suggest that SARS-Cov2 could lead to adoptive immune disorder while remain active viral replication. In this report, we have demonstrated that SARS-CoV-2 ORF8 mediates MHC-I downregulation, which is not observed in any other strains of SARS-CoV. The discrepancy of ORF8 between SARS-CoV-2 and SARS-CoV could at least partially be responsible for specific COVID-19 clinical and pathological characteristics, which somehow behaves as a chronic viral infection.
  231.  
  232. https://www.biorxiv.org/content/10.1101/2020.05.24.111823v1
  233. ----------------------------------------------------------
  234. >Dengue Fever, COVID ‐19 (SARS‐CoV ‐2), and Antibody‐Dependent Enhancement (ADE ): A Perspective
  235. Here, we review the possible antibody‐dependent enhancement (ADE) occurrence, known for dengue infections, when there is a second infection with a different virus strain. Consequently, preexisting antibodies do not neutralize infection, but enhance it, possibly by triggering Fcγ receptor‐mediated virus uptake. No clinical data exist indicating such mechanism for SARS‐CoV‐2, but previous coronavirus infections or infection of SARS‐CoV‐2 convalescent with different SARS‐CoV‐2 strains could promote ADE, as experimentally shown for antibodies against the MERS‐CoV or SARS‐CoV spike S protein.
  236. https://onlinelibrary.wiley.com/doi/full/10.1002/cyto.a.24047
  237. http://archive.is/oeoyA
  238. ----------------------------------------------------------
  239. Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures
  240. >Here, we highlight clinical and experimental observations from earlier CoV outbreaks and suggest strategies that may reduce ADE in treating the SARS-CoV-2 pandemic. Whether SARS-CoV-2 can cause ADE effects remains an open question.
  241. >Epidemiological studies investigating ADE in individuals with multiple SARS-CoV-2 infections or cross-reactivity to common-cold-causing CoVs will likely take several years. However, given that ADE has been observed with the closely related SARS-CoV, we believe that the question of ADE effects in SARS-CoV-2 should be urgently resolved using experimental immunology.
  242. >As a cautionary note, no effort has yet been able to identify epitopes that can fully avoid the problem of ADE for any single viral pathogen associated with the phenomenon.
  243. https://www.nature.com/articles/s41587-020-0577-1
  244. http://archive.is/gVLtJ
  245.  
  246.  
  247. --------------------------------------------------------------------------------------------------------------------
  248. Individuals infected with earlier SARS-CoV-2 coronavirus strains could be defenseless against more aggressive European strains with the D614G mutations.
  249. >Antibodies found in blood of individuals who have fought the disease previously failed to stop the D614G strain.
  250. >The mutant form was collected from Beijing's current outbreak
  251. >Dr Ailong said that there is an urgent need to determine what threat this mutation poses to people who have recovered from a different form of the virus. Also worrisome is that the new strain could actually be more worse the second time round in patients who were previously infected with the milder strains and recovered
  252. >The strain with the D614G mutation began spreading in Europe in early Feb and by May was the dominant strain around the world, presenting in 70% of sequenced samples in Europe and North America. It is now in India, Iran, Middle-East and Brazil
  253. >12% of the newly infected in Beijing are in critical condition
  254. >Virus was found in the mouths of imported salmon among other places.
  255. >Dr Huang and his team selected a strain of the virus that had previously circulated China and manipulated it to create a man-made version containing the mutation
  256. >They extracted antibodies from 41 blood samples from recovered patients and pitched them against the mutant. All failed to fight the new strain.
  257. >San Diego report reveals D614G mutation has the potential to increase the number of spike proteins on the coronavirus and boost its ability to infect human cells by a factor of 10.
  258. >1 of the concerns now is whether the mutated D614G strain will devastate vaccine development since the current vaccines reaching final trials are based on the Wuhan strain.D614G mutation could reduce the effectiveness of vaccines that target the virus’ spike protein
  259. >It must be noted that here are also other strains with mutations on them being discovered, with another 2 more that might be even more potent.
  260.  
  261.  
  262. https://www.thailandmedical.news/news/warning-d614g-mutation-coronavirus-strains-from-europe-could-render-those-recovered-from-earlier-strains-defenseless-according-to-china
  263.  
  264. The D614G mutation of SARS-CoV-2 spike protein enhances viral infectivity and decreases neutralization sensitivity to individual convalescent sera
  265. https://www.biorxiv.org/content/10.1101/2020.06.20.161323v1
  266. https://archive.is/gRm6C
  267.  
  268. --------------------------------------------------------------------------------------------------------------------
  269. Антитела - недолговременные
  270. Prevalence of IgG antibodies to SARS-CoV-2 in Wuhan - implications for the ability to produce long-lasting protective antibodies against SARS-CoV-2
  271. https://www.medrxiv.org/content/10.1101/2020.06.13.20130252v1
  272.  
  273. There may be no immunity against Covid-19, new Wuhan study suggests
  274. https://www.scmp.com/news/china/science/article/3089476/there-may-be-no-immunity-against-covid-19-new-wuhan-study
  275.  
  276. ----------------------------------------------------------
  277. Viral reactivation in Italian patient
  278. http://archive.is/NTHMj
  279. ----------------------------------------------------------
  280. Sailors on Sidelined Carrier Get Virus for Second Time
  281. http://archive.is/1izfx
  282. ----------------------------------------------------------
  283. Re-infected patients had low protective antibodies
  284. http://archive.is/2ZqJP
  285. ----------------------------------------------------------
  286. Coronaviruses and re-infections overview
  287. http://archive.is/zLZNY
  288. ----------------------------------------------------------
  289. Case study of SARS2/influenza co-infected patient
  290. http://archive.is/vSjms
  291. ----------------------------------------------------------
  292. Иммунитет выживших сильно ослаблен
  293. https://archive.is/2EQ6x
  294. ----------------------------------------------------------
  295. SARS2 and co-infections*
  296. http://archive.is/OGgqg
  297. https://www.sciencedirect.com/science/article/pii/S1684118220301274
  298. ----------------------------------------------------------
  299. Reactivation/chronic illness from SARS-CoV2
  300. The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I
  301. https://www.biorxiv.org/content/10.1101/2020.05.24.111823v1
  302. ---------------------------------------------------------------------------------------------------------------------------
  303. ТЕСТЫ - ХУЙНЯ
  304. ---------------------------------------------------------------------------------------------------------------------------
  305. https://archive.is/mJOrA (Nature)
  306. also https://covid19testingkits.org/wp-content/uploads/2020/04/Product-Insert-B21888-01-COVID-19-IgG-IgM.pdf
  307. >Positive results may be due to past or present infection with non-SARS-CoV-2 coronavirus strains
  308.  
  309. Antibody tests vastly underperform advertised accuracy
  310. https://archive.is/MGJrW
  311. https://www.medrxiv.org/content/10.1101/2020.04.15.20066407v1.full.pdf
  312.  
  313. New antigen tests are inaccurate
  314. https://www.sciencemag.org/news/2020/05/coronavirus-antigen-tests-quick-and-cheap-too-often-wrong
  315. http://archive.is/a2QBG
  316. ---------------------------------------------------------------------------------------------------------------------------------
  317. Вакцины терпят крах
  318. Oxford vaccine doesn't prevent infections (op-ed)
  319. https://blogs.sciencemag.org/pipeline/archives/2020/05/18/criticism-of-the-oxford-coronavirus-vaccine
  320.  
  321. Harvard Prof: Oxford vaccine is ineffective
  322. https://www.forbes.com/sites/williamhaseltine/2020/05/16/did-the-oxford-covid-vaccine-work-in-monkeys-not-really/#3f3c240a3c71
  323.  
  324. ---------------------------------------------------------------------------------------------------------------------------------
  325. ЦНС и мозг
  326. https://pastebin.com/raw/6wGeMfrG
  327. ---------------------------------------------------------------------------------------------------------------------------------
  328. RESOURCES FOR NEUROLOGICAL COMPLICATIONS/SYMPTOMS IN COVID-19
  329. https://www.ean.org/ean/eancore-covid-19
  330. https://braininfectionsglobal.tghn.org/covid-neurology-resource/
  331. -------------------------------------------------------------------------------------------
  332. Пруфы нейротоксичности вируса
  333. http://archive.is/byMqw
  334. https://www.preprints.org/manuscript/202005.0365/v1
  335. https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmv.25728
  336. -------------------------------------------------------------------------------------------
  337. Spectrum of neurological manifestations associated with SARS-CoV-2 infection
  338. Can lead to:
  339. >Acute Encephalopathy
  340. >Seizures / Status Epilepticus
  341. >Acute Hemorrhagic Necrotizing Encephalopathy
  342. >Ischemic Stroke / Intra Cerebral Hemorrhage / Cerebral Venous Sinus Thrombosis
  343. >Encephalitis
  344. >Demyelinating lesions
  345. >Guillain-Barré Syndrome / Miller Fisher Syndrome
  346. >Posterior Reversible Encephalopathy Syndrome
  347. >Subjective neurological symptoms
  348. https://ictalgroup.org/2020/04/08/spectrum-of-neurological-manifestations-associated-with-sars-cov-2-infections/
  349. -------------------------------------------------------------------------------------------
  350. SARS-CoV-2 targets cortical neurons of 3D human brain organoids and shows neurodegeneration-like effects
  351. https://www.biorxiv.org/content/10.1101/2020.05.20.106575v1
  352. http://archive.li/CjHEa
  353. -------------------------------------------------------------------------------------------
  354. ПОВРЕЖДЕНИЯ/ИНФИЦИРОВАНИЕ ЦНС
  355. SARS2 and the nervous system
  356. http://archive.is/K64wc
  357. https://link.springer.com/article/10.1007/s13365-020-00840-5
  358.  
  359. COVID-19: A Systematic Review of The Mechanisms of Injury to The Central Nervous System This Far
  360. 2019-nCoV has an alarming potential to affect the nervous system, and to cause serious illnesses such as seizures, hemorrhagic or ischemic strokes, encephalitis, meningitis, Guillain-Barré Syndrome, and many others.
  361. There is strong evidence supporting the link between 2019-nCoV and nervous damage, and that there are at least three means by which it may directly enter the CNS, and three by which it may cause indirect harm to the CNS
  362. https://iajmh.emnuvens.com.br/iajmh/article/view/115
  363. -------------------------------------------------------------------------------------------
  364. There's two ways the virus appears to enter the CNS, through the olfactory nerve and through BBB breakdown. The olfactory route is the mechanism behind common early symptoms like anosmia.
  365. >Once SARS-CoV-2 reaches the olfactory bulb, it may target the deeper parts of the brain including the thalamus and brainstem by trans-synaptic transfer as described for many viral disease
  366. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192347/
  367. But BBB breakdown is associated with acute systemic inflammation
  368. >the intense systemic inflammatory response linked to viral infection can lead to blood–brain barrier (BBB) breakdown. This in turn can allow peripheral cytokines to gain access to the CNS, where they may trigger or exacerbate neuroinflammation leading to encephalitis
  369. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172664/
  370. -------------------------------------------------------------------------------------------
  371. [b]Coronavirus: Neuropsychiatric symptoms and immunologic mechanisms[/b]
  372. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152874/
  373. https://www.frontiersin.org/articles/10.3389/fneur.2020.00498/abstract
  374. -------------------------------------------------------------------------------------------
  375. SARS2 is "neurotoxin-like"
  376. http://archive.is/QKJc8
  377. -------------------------------------------------------------------------------------------
  378. SARS-CoV-2 can induce brain and spine demyelinating lesions
  379. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197630/
  380. -------------------------------------------------------------------------------------------
  381. Review of neurological conditions
  382. http://archive.is/fm94T
  383. -------------------------------------------------------------------------------------------
  384. Neuroradiological features in coronavirus patients: first evidence in a complex scenario
  385. http://archive.is/TlxB3
  386. -------------------------------------------------------------------------------------------
  387. SARS2 enters neurons within 2 days of infections, neurodegenerative
  388. http://archive.is/CjHEa]
  389. -------------------------------------------------------------------------------------------
  390. Loss of taste/smell fourth most common symptom
  391. http://archive.is/8Ii0r
  392. -------------------------------------------------------------------------------------------
  393. Taste disorders present in half of SARS2 cases
  394. https://www.gastrojournal.org/article/S0016-5085(20)30595-3/fulltext
  395. http://archive.is/lyuHN
  396. -------------------------------------------------------------------------------------------
  397. Meningoencephalitis Without Respiratory Failure in a Young Female Patient With COVID-19 Infection in Downtown Los Angeles
  398. https://pubmed.ncbi.nlm.nih.gov/32305574/
  399. -------------------------------------------------------------------------------------------
  400. Continuous Electroencephalography (cEEG) Characteristics and Acute Symptomatic Seizures in COVID-19 Patients
  401. https://www.medrxiv.org/content/10.1101/2020.05.26.20114033v1
  402. -------------------------------------------------------------------------------------------
  403. Стволовые клетки
  404. Lung epithelial stem cells express SARS-CoV-2 entry factors: implications for COVID-19
  405. https://www.biorxiv.org/content/10.1101/2020.05.23.107334v1
  406. -------------------------------------------------------------------------------------------
  407. Neuropilin-1 is a host factor for SARS-CoV-2 infection
  408. https://www.biorxiv.org/content/10.1101/2020.06.05.134114v1
  409. -------------------------------------------------------------------------------------------
  410. Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system
  411. https://www.biorxiv.org/content/10.1101/2020.06.07.137802v1
  412. -------------------------------------------------------------------------------------------
  413. Neutrophils maybe causing viral sepsis and MIS-C
  414. http://archive.is/HfadL
  415. -------------------------------------------------------------------------------------------
  416. Reactivation/neurodamage of SARS2 mirrors Nipah virus
  417. http://archive.is/p6nOm
  418. -------------------------------------------------------------------------------------------
  419. Brainstem involvement in fatal SARS2 cases
  420. http://archive.is/Q46iL
  421. -------------------------------------------------------------------------------------------
  422. Longterm neurological consequences of SARS2
  423. http://archive.is/6cwbT
  424. -------------------------------------------------------------------------------------------
  425. Review: neuropsychiatric aspects of SARS2
  426. http://archive.is/2wBXi
  427. -------------------------------------------------------------------------------------------
  428. 31/71 patients experienced SARS2 delirium
  429. http://archive.is/pqkl4
  430. -------------------------------------------------------------------------------------------
  431. Encephalopathy in SARS2, no BBB cross
  432. http://archive.is/EWP6e
  433. -------------------------------------------------------------------------------------------
  434. Ischemic brain damage in SARS2 patients
  435. http://archive.is/UALgD
  436. -------------------------------------------------------------------------------------------
  437. ICUs Become A ‘Delirium Factory’ For COVID-19 Patients
  438.  
  439. >Although COVID-19 is best known for damaging the lungs, it also increases the risk of life-threatening brain injuries — from mental confusion to hallucinations, seizures, coma, stroke and paralysis. The virus may invade the brain, as well as starve the organ of oxygen by damaging the lungs. To fight the infection, the immune system sometimes overreacts, battering the brain and other organs it normally protects.
  440. >Some of the best-known symptoms of COVID-19 might be caused by the virus invading the brain, said Dr. Robert Stevens, an associate professor of anesthesiology and critical care medicine at Johns Hopkins University.
  441. >Many COVID patients develop “silent hypoxia,” in which they are unaware that their oxygen levels have plummeted dangerously low, Stevens added. When hypoxia occurs, regulatory centers in the brain stem — which control respiration — signal to the diaphragm and the muscles of the chest wall to work harder and faster to get more oxygen into the body and force out more carbon dioxide, Stevens said. The lack of this response in some patients with COVID-19 could indicate the brain stem is impaired.
  442.  
  443. http://archive.is/K0Nqz
  444. --------------------------------------------------------------------------------------------------------------------------------
  445.  
  446. --------------------------------------------------------------------------------------------------------
  447. Critically ill SARS-CoV-2 patients display lupus-like hallmarks of extrafollicular B cell activation
  448. http://archive.li/5JiBd
  449. >permanent lung damage?
  450. >SARS-Cov2 enables anaerobic bacteria (Prevotella, et al) to colonize the lungs disrupting homeostasis - symptoms (ARDS, septic shock, blood clots, arterial stroke) finds resonance, with key differences, in the ‘forgotten disease’ Lemierre Syndrome
  451. osf.io/usztn/
  452. >for the first time, SARS-CoV-2 invasion of the placenta, highlighting the potential for severe morbidity among pregnant women with coronavirus.
  453. medrxiv.org/content/10.1101/2020.04.30.20083907v1
  454.  
  455. Coronavirus may lurk deep in lungs after patients recover, study suggests
  456. http://archive.is/AoZZJ
  457.  
  458. https://www.medrxiv.org/content/10.1101/2020.03.29.20041962v2
  459. Highly pathogenic coronavirus N protein aggravates lung injury by MASP-2-mediated complement over-activation
  460.  
  461. >Actor Nick Cordero struggling to survive Coronachan gave him blood clots that lead to necessary leg amputation, wife says his healthy lungs deteriorated to that of a 50 year old heavy smoker
  462. goodmorningamerica.com/wellness/story/broadway-star-nick-cordero-holes-lungs-battle-covid-70449370
  463.  
  464. >Most who "recovered" haven't actually recovered
  465. >researchers found mild to significant lung abnormalities on the chest computed tomography (CT) images of 94 percent of patients with coronavirus upon discharge from the hospital, suggesting follow-up monitoring of patients might be necessary.
  466. itnonline.com/content/study-looks-ct-findings-covid-19-through-recovery
  467.  
  468. Coronavirus patient puzzles New York doctors with rare symptoms
  469. >patient’s lungs indicated a fungal invasion
  470. >He developed a cytokine storm within a few hours of the disease’s onset, something that rarely happens so quickly
  471. http://archive.is/LF4oe
  472.  
  473. Strokes in young patients 20s-30s rapidly growing
  474. http://archive.is/MW1SL
  475.  
  476. -----------------------------------------------------------------------------------------------------------------------
  477. ГЛАЗА
  478. CAN SARS2 DAMAGE THE EYES?
  479.  
  480. >All patients showed hyper-reflective lesions at the level of ganglion cell and inner plexiform layers more prominently at the papillomacular bundle in both eyes. Ganglion cell and plexiform layer findings could be associated with CNS manifestations that have been described in animal studies and in COVID-19 neurological events
  481. http://archive.is/mz7gn
  482.  
  483. >The ocular implications of human CoV infections have not been widely studied. However, CoVs have been known to cause various ocular infections in animals. Clinical entities such as conjunctivitis, anterior uveitis, retinitis, and optic neuritis have been documented in feline and murine models
  484. http://archive.is/2sOYQ
  485.  
  486. >Across all eye specimens, immunohistochemical analysis revealed expression of ACE2 in the conjunctiva, limbus, and cornea, with especially prominent staining in the superficial conjunctival and corneal epithelial surface. Surgical conjunctival specimens also showed expression of ACE2 in the conjunctival epithelium, especially prominent in the superficial epithelium
  487. http://archive.is/rhgAq
  488.  
  489. >It cannot be excluded that SARS-CoV-2 could both infect the eye and the surrounding structures. SARS-CoV-2 may use ocular structure as an additional transmission route, as demonstrated by the COVID-19 patients’ conjunctival secretion and tears positivity to reverse transcriptase-PCR SARS-CoV-2-RNA assay.
  490. http://archive.is/wLxe9
  491.  
  492. >12 patients had ocular manifestations, such as epiphora, conjunctival congestion, or chemosis, and these commonly occurred in patients with more severe systemic manifestations...more significant changes in blood test values appeared in patients with ocular abnormalities
  493. http://archive.is/1q5Fn
  494.  
  495. >Fifteen (27%) had aggravated ocular symptoms, of which 6 (11%) had prodromal ocular symptoms before disease onset. Ocular symptoms are relatively common in COVID-19 disease and may appear just before the onset of respiratory symptoms
  496. http://archive.is/yXzA4
  497.  
  498. >ACUTE VISION LOSS IN A PATIENT WITH COVID-19
  499. https://www.medrxiv.org/content/10.1101/2020.06.03.20112540v1
  500.  
  501. >Transient cortical blindness in COVID-19
  502. https://www.jns-journal.com/article/S0022-510X(20)30194-5/pdf
  503. -----------------------------------------------------------------------------------------------------------------------
  504. -----------------------------------------------------------------------------------------------------------------------
  505. Дети.
  506. Characteristics and Outcomes of Children With Coronavirus
  507. https://jamanetwork.com/journals/jamapediatrics/fullarticle/2766037
  508.  
  509. "Hyperinflammatory shock in children during coronavirus pandemic"
  510. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31094-1/fulltext
  511.  
  512. >SHOW ME SIGNIFICANT DEATHS OF THE YOUNG AND HEALTHY IN ANY COUNTRY
  513. Count all the latest kawasaki deaths then
  514. Outbreak of Kawasaki disease in children during coronavirus pandemic: a prospective observational study in Paris, France
  515. http://archive.is/Qn3Ne
  516. --------
  517. Kawasaki Disease: The Role of Immune Complexes Revisited
  518. https://www.frontiersin.org/articles/10.3389/fimmu.2019.01156/full
  519.  
  520. https://www.ahajournals.org/doi/10.1161/circ.131.suppl_2.54
  521.  
  522. Abstract 54: The Correlation Between IgE And The Level Of Interleukin-21 In Kawasaki Disease
  523. --------
  524. https://synapse.koreamed.org/search.php?where=aview&id=10.4078/jrd.2013.20.1.4&code=1010JRD&vmode=PUBREADER
  525.  
  526. Relation between Kawasaki Disease and Immunoglobulin E
  527. ---------
  528. https://www.nature.com/articles/pr2009122
  529.  
  530. Molecular Genetics of Kawasaki Disease
  531. ------------
  532. https://www.frontiersin.org/articles/10.3389/fped.2019.00018/full
  533. Causes of Kawasaki Disease—From Past to Present
  534. -----
  535. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047536/
  536.  
  537. >2 Kids and a Teenager dead in New York
  538. http://archive.is/BN5Dm (CNN, 10/05)
  539. http://archive.is/fSqVH (RT, 10/05)
  540. >15 cases in Paris, 70 in New York
  541. http://archive.is/txKpf (German tagesschau, 14/05)
  542. >First fatality in France is a 14-year old with no underlying conditions
  543. http://archive.is/DPSIy (France24, 15/05)
  544. >Researchers at the Imperial College London early in developing a test
  545. http://archive.is/VCEQx (FOX, 20/05)
  546. >Kawasaki-like syndrome now called PMIS (paediatric multisystem inflammatory syndrome) or MIS-C (multisystem inflammatory syndrome in children)
  547. >20 cases in Bergamo, Italy with Kawasaki symptoms - more than the past 5 years combined
  548. >Other affected children develop persistent fevers
  549. http://archive.is/Z4guz (Al-Jazeera, 21/05)
  550.  
  551. MIS-C / PMIS / Kawasaki-like syndrome update
  552. >Symptoms include stomach pains, fever, rashes
  553. >heart damage all but confirmed
  554. >Six weeks asymptomatic incubation
  555. http://archive.is/HssbI (CNN, 20/05)
  556. >Two cases at Seattle Children's, 13 and 10
  557. http://archive.is/DRuOy (KIRO7, 22/05)
  558. >38% of cases have acute kidney injury
  559. >51% got myocardial impairment
  560. >75% went into shock
  561. http://archive.is/9Tg5H (DAIC, 20/05)
  562.  
  563. Heart failure in inflammatory syndrome in children in coronavirus pandemic
  564. http://archive.vn/YngG1
  565.  
  566. https://archive.vn/fPgBc
  567. young adults can also get strange kawasaki like symptoms
  568.  
  569. Up to 5 NY Children Dead, 93 Sickened by Rare Coronavirus-Related Illness
  570. http://archive.is/BERaE
  571.  
  572. Children have lower viral loads than adults
  573. http://archive.is/yP27O
  574.  
  575. SARS2: severe childhood disease needing specialist care
  576. http://archive.is/IiKeK
  577. >but they're "no worse" than other sick children in specialist hospitals, i.e. cancer patients
  578.  
  579. Fatal Central Nervous System Co-Infection with SARS-CoV-2 and Tuberculosis in a Healthy Child
  580. >The detection of SARS-CoV-2 RNA in cerebellar tissue and the demonstration of seroconversion in IgG and IgA assays was consistent with acute SARS-CoV-2 infection of the central nervous infection. However, the cause of death was brain herniation from her rapidly progressive central nervous system tuberculosis. SARS-CoV-2 may mask or worsen occult tuberculous infection with severe or fatal consequences.
  581. https://www.researchsquare.com/article/rs-33272/v1
  582. ---------------------------------------------------------------------------------------------------------------------------
  583. Беременные
  584.  
  585. Placentas from COVID-19-positive pregnant women show injury
  586. https://news.northwestern.edu/stories/2020/05/placentas-from-covid-19-positive-pregnant-women-show-injury
  587.  
  588. SARS-CoV-2 invasion of the placenta, highlighting the potential for severe morbidity among pregnant women with coronavirus.
  589. medrxiv.org/content/10.1101/2020.04.30.20083907v1
  590. ---------------------------------------------------------------------------------------------------------------------------
  591. Локдауны и меры
  592.  
  593. Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe
  594. https://www.nature.com/articles/s41586-020-2405-7
  595.  
  596. The effect of large-scale anti-contagion policies on the COVID-19 pandemic
  597. https://www.nature.com/articles/s41586-020-2404-8_reference.pdf
  598.  
  599. Fear and knowledge of SARS2 by region
  600. https://www.medrxiv.org/content/10.1101/2020.05.26.20113233v1
  601. http://archive.is/k07jC
  602.  
  603. 55% of US deaths caused by 1-week lockdown delay
  604. http://archive.is/ECxx5
  605.  
  606. Models with linear curves may be wrong
  607. http://archive.is/RttwF
  608.  
  609. Masks & city disinfection needed to slow spread
  610. http://archive.is/SASx3
  611.  
  612. Governance of lockdowns
  613. http://archive.is/YdC0p
  614.  
  615. NY SARS2 higher viral loads than Chicago SARS2
  616. https://www.medrxiv.org/content/10.1101/2020.05.19.20107144v1
  617. http://archive.is/iq3t3
  618.  
  619. US: biggest clusters NYC, NOLA, Chi
  620. https://www.medrxiv.org/content/10.1101/2020.05.22.20110155v1
  621. http://archive.is/labfF
  622. -------------------------------------------------------------------------------------------
  623. Температура и для летомпройдёт шизиков
  624. No evidence for less transmission above T=26C/80F*
  625. http://archive.is/tGvA6
  626. -------------------------------------------------------------------------------------------
  627. Про заражения до января в Европе и США - их не было.
  628. The emergence of SARS-CoV-2 in Europe and the US
  629. >Infections in US and EU didn't happen before Jan
  630. https://www.biorxiv.org/content/10.1101/2020.05.21.109322v1
  631. -------------------------------------------------------------------------------------------
  632.  
  633. ---------------------------------------------------------------------------------------------------------------------------
  634. Смертность
  635. Observed CFR is dependent on actual testing rate
  636. http://archive.is/AeX83
  637.  
  638. The illusion of confirmed cases
  639. http://archive.is/dHiT5
  640.  
  641. 26% пациентов за пределами Китая умерли
  642. Peer reviewed
  643. http://archive.is/Hfqx9
  644. http://archive.is/MsJBC
  645. >In the largest-ever study of coronavirus cases outside China, 26% of patients died. Their symptoms came in ‘clusters.’
  646. https://www.bmj.com/content/369/bmj.m1985
  647.  
  648. Sweden: "worst outbreak since Spanish flu"
  649. http://archive.is/JABnB
  650.  
  651. Excess mortality in England at height of SARS2
  652. https://www.medrxiv.org/content/10.1101/2020.05.26.20113357v1
  653. http://archive.is/w5QzX
  654.  
  655.  
  656. Факторы риска и группы риска
  657. A review of risk factors for mortality in SARS2*
  658. https://onlinelibrary.wiley.com/doi/10.1002/jmv.26050
  659.  
  660. US CFR ~4.85%, smoking has no affect on mortality
  661. http://archive.is/GEC5l
  662. ---------------------------------------------------------------------------------------------------------------------------
  663. SARS2 and the nicotinic cholinergic system
  664. http://archive.is/H2TqG
  665.  
  666. Chromobacterium as broad spectrum anti-virals
  667. http://archive.is/Az046
  668.  
  669. Open data resources for SARS2
  670. http://archive.is/r4tIP
  671. -----------------------------------------------------------------------------------------------------------------------------
  672. Учёные в говне мочёные.
  673.  
  674. https://www.mercurynews.com/2020/05/24/coronavirus-research-stanford-scientists-accused-of-hyping-covid-19-antibody-study/amp/
  675. >disseminating information about their research, offering it quickly and without filters in the effort to understand and control
  676. > new communication model is striking at the heart of scientific integrity, publicizing research that has been corrupted by speed, sloppiness and opacity
  677. >Stanford University, where a trio of researchers are accused of promoting faulty analysis and “tipping the scale” on antibody studies that they say proves the virus is more widespread and less lethal than we feared, and that public health restrictions are too strict
  678. >Peer review? It’s raucous and transparent, crowdsourced — via email and Twitter — by scores of commentators.
  679. >more than 10,000 COVID-related papers have been published since January
  680. >29 studies were published during the 2003 SARS pandemic
  681. >too much research lacks rigor and responsibility, experts say. Methods aren’t explained; statistical analyses aren’t transparent. Breaking from the usual protocol, testing is rushed into human study before completion of more basic work
  682. >Treatment trials are using flawed strategies. There is duplication of effort, creating waste
  683. >tests of the new Moderna vaccine, researchers didn’t wait to see how well it prevents infection in animals before trying it in people and tests involving just eight people, the company revealed very little data about the vaccine’s success
  684. >“When we do research under pandemic conditions, it is important to maintain the same standard of rigor as we would outside a pandemic,”
  685. >The nation’s first study of its type, it found that the virus was astoundingly 50 to 85 times more prevalent than presumed. But that meant the death rate was far lower.Yet the project raised eyebrows from the start. Even before they started collecting data, the researchers openly questioned “stay at home” orders.
  686. http://archive.is/RX9Rc
  687. -----------------------------------------------------------------------------------------------------------------------------
  688. Несортированное
  689.  
  690. Sensitivity of antibody assays
  691. http://archive.is/xiiyG
  692. http://archive.is/gavvB
  693. http://archive.is/4ovjC
  694.  
  695. Zinc as a prophylactic
  696. http://archive.is/YCVvM
  697.  
  698. Over 1300 introductions of SARS2 into UK
  699. http://archive.is/KpGPI
  700.  
  701. Findings of NYC SARS2-MISC cases
  702. http://archive.is/raOh9
  703.  
  704. Deterioration of SARS2 pts with GI symptoms
  705. http://archive.is/Gv0oc
  706.  
  707. SARS2 pulmonary post-mortem findings
  708. http://archive.is/FaCi9
  709.  
  710. Molecular profile of severe SARS2
  711. http://archive.is/LRNfi
  712.  
  713. Review of myocardial injury in SARS2
  714. http://archive.is/x7bms
  715.  
  716. SARS2 on the male reproductive system
  717. http://archive.is/ftKXB
  718.  
  719. 74% of people moderately to strongly believe SARS2 has lab origins
  720. http://archive.is/8jXee
  721.  
  722. Excess deaths in Italy by region
  723. http://archive.is/YKkV1
  724.  
  725. Viral load infectious regardless of age, symptoms
  726. http://archive.is/WQ1Es
  727.  
  728. High degree of asymptomatic transmission among nurses
  729. http://archive.is/Wyiz6
  730.  
  731. Misinformation, social norms driving icarus effect of SARS2
  732. http://archive.is/ibedp
  733.  
  734. SARS2 "fake news" is endemic to source country
  735. http://archive.is/uBRWr
  736.  
  737. "Fake news" bots tweeting as much as NYT/CDC
  738. http://archive.is/jSwK9
  739.  
  740. G614 mutation neutral to protein function
  741. http://archive.is/t2bgP
  742.  
  743. NETs driving SARS2 sepsis pathologies
  744. http://archive.is/WGMnJ
  745. (NETs are thought to enhance hypercoagulation in HIV patients http://archive.is/Gro4C)
  746.  
  747. Estimation of global CFR
  748. http://archive.is/vJtOz
  749.  
  750. Case study of negative swab SARS2 patient
  751. http://archive.is/uyk0f
  752.  
  753. Cattle may have been an intermediate host*
  754. https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.25817
  755. http://archive.is/NkSld
  756.  
  757. Second waves over wide range of model scenarios
  758. http://archive.is/Ti21i
  759.  
  760. A2H, H2A, should we be concerned?
  761. http://archive.is/I9ovC
  762.  
  763. Virus lineage in Thailand, truncated ORF7a
  764. http://archive.is/RXEWf
  765.  
  766.  
  767. https://archive.vn/WcH7Q
  768. Non lung related symptoms of commie coof a summary
  769.  
  770. How SARS2 pandemic has changed pre-print literature
  771. http://archive.is/SfaV6
  772.  
  773. Mechanism for how famotidine fights SARS2
  774. http://archive.is/qPfzI
  775.  
  776.  
  777. Abnormal liver markers among SARS2 patients
  778. http://archive.is/iCrhN
  779.  
  780.  
  781. https://archive.vn/josvg
  782. swedish herd immunity is a long way off if they ever reach it
  783.  
  784. https://archive.vn/jwWiT
  785. france recording 70 new cases of corona after 1 week of reopening schools
  786.  
  787.  
  788. Half of COVID tweets are by misinformation bots
  789. http://archive.is/vYwob
  790.  
  791. SARS2 found in heart, eyes, brain of hACE2 knockout mice
  792. http://archive.is/dk5Zk
  793.  
  794. Call for transparency in SARS2 modelling
  795. http://archive.is/Gnm11
  796.  
  797. Tennessee's 'open test policy' slowing spread
  798. http://archive.is/tcrON
  799.  
  800. Simulation of repurposed drugs for SARS2
  801. http://archive.is/NjJ6k
  802.  
  803. Never seen": COVID hijacks cells, DNA
  804. http://archive.is/XwTOn
  805.  
  806. UK: PPE goes thru 4 levels of profit skimming
  807. http://archive.is/6joLU
  808.  
  809. Canada MD: "Pandemics are never one wave"
  810. http://archive.is/drMz2
  811.  
  812. China launched 90k tweets of disinformation
  813. http://archive.is/WxWQN
  814.  
  815. Brazil new epicenter of global pandemic
  816. http://archive.is/0PtE2
  817.  
  818. 1 out of 4 Americans hesistant about vaccine
  819. http://archive.is/sx75M
  820.  
  821. Delay in lockdowns caused 30k extra US deaths
  822. http://archive.is/zfi1V
  823.  
  824. Jewish doctors treating COVID with marijuana
  825. http://archive.is/TWhY4
  826.  
  827. 80% of infections are caused by 10% of people
  828. http://archive.is/bWuL7
  829.  
  830. China again seizes control of PPE factories
  831. http://archive.is/3SahP
  832.  
  833. Experts: US has 3 months to prepare for 2nd wave
  834. http://archive.is/AjnXR
  835.  
  836. Top HIV scientist says SARS2 vaccine highly unlikely
  837. http://archive.is/tcH9b
  838.  
  839. US meat safety largely unenforced
  840. http://archive.is/BKJN5
  841.  
  842. Half of COVID tweets are by bots
  843. http://archive.is/TKdLB
  844.  
  845. Newborn dies in South Africa
  846. http://archive.is/iW38v
  847.  
  848. 87% of US nurses reusing PPE
  849. http://archive.is/EItzr
  850.  
  851. Cambridge: Online only until summer 2021
  852. http://archive.is/lEKe3
  853.  
  854. Sweden nowhere near herd immunity
  855. http://archive.is/fdCXI
  856.  
  857. CDC is inflating ability to test
  858. http://archive.is/vDdNJ
  859.  
  860. Cloth masks are political not scientific
  861. http://archive.is/vEFsN
  862.  
  863. Italy put COVID patients in nursing homes
  864. http://archive.is/WiTpK
  865.  
  866. Over 122,000 deaths went unreported in 14 countries
  867. https://archive.is/Qlutx
  868.  
  869. Almost all countries only report deaths that occur in hospitals
  870. https://archive.is/rZp0M
  871.  
  872. Hispanics and blacks account for most deaths in California
  873. https://archive.is/FJAsj
  874.  
  875. For coronaviruses, antibodies don't guarantee immunity
  876. https://archive.is/BV4CI
  877.  
  878. Novel coronavirus can survive high temperatures
  879. https://archive.is/SxQDu
  880.  
  881. Italy doesn't report deaths at home and nursing homes
  882. https://archive.is/zWJw1
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