<form [formGroup]="form">
    <input type="text" id="name" formControlName="name" />
    <input type="text" id="age" formControlName="age" />
</form>

ngOnInit() {

     this._route.queryParams.subscribe(params => {
            getUser(params.userId).subscribe(user => {
                 this._buildForm(user);
            })
     });
}

private _buildForm(user){
    this.form = _fb.group({
        name: [{value: user.name, disabled: user.someCondition}, Validators.required],
        age: [{value: user.age, disabled: user.anotherCondition}, Validators.required]
    })
}

this.form.disable() //Doesn't do anything

this.form.controls.name.disable(); //Doesn't help

<button (click)="form.disable()" value="Disable Form" />
<button (click)="form.enable()" value="Enable Form" />

this._router.navigate([], {
   relativeTo: this._route,
   queryParams: {userId: 10}
})

@Component({
  selector: 'my-app',
  templateUrl: './app.component.html',
  styleUrls: [ './app.component.css' ]
})
export class AppComponent  {
  group;
  isDisabled = true;

  constructor(fb: FormBuilder) {
    this.group = fb.group({
      stuff: fb.control({value: 'stuff', disabled: this.isDisabled})
    });
  }

  toggle() {
    this.isDisabled = !this.isDisabled;

    this.group.controls.stuff[this.isDisabled ? 'enable' : 'disable']();
  }
}

<form [formGroup]="form" (submit)="_updateForm()">
    <input type="text" id="name" fromControlName="name" />
    <input type="text" id="age" fromControlName="age" />
</form>

private userId: any;


ngOnInit() {
    this._route.queryParams.subscribe(params => {
        this.userId = params.userId;
        this._updateForm();
    });
}

private _buildForm(user){
    this.form = _fb.group({
        name: [{value: user.name, disabled: user.someCondition}, Validators.required],
        age: [{value: user.age, disabled: user.anotherCondition}, Validators.required]
    });
}

// The update function has to be public to be called inside your template
public _updateForm(){
    getUser(this.userId).subscribe(user => {
        this._buildForm(user);
    });
}

<form [formGroup]="form">
    <input type="text" id="name" fromControlName="name" />
    <input type="text" id="age" fromControlName="age" />
</form>