File access

import struct

thefile = open('somebinfile', 'r+b')
record_size = struct.calcsize(format_string)

thefile.seek(record_size * record_number)
buffer = thefile.read(record_size)
fields = list(struct.unpack(format_string, buffer))

# Perform computations, suitably modifying fields, then:

buffer = struct.pack(format_string, *fields)
thefile.seek(record_size * record_number)
thefile.write(buffer)

thefile.close(  )