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Apr 24th, 2019
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  1. {
  2.     "$schema": "http://json-schema.org/draft-07/schema#",
  3.     "$id": "https://pastebin.com/raw/k97EgrxD"
  4.     "description": "Spreadsheet describing associations.",
  5.     "additionalProperties": false,
  6.     "required": [
  7.         "study_tag",
  8.         "variant_id",
  9.         "pvalue",
  10.         "effect_allele",
  11.         "effect_allele_frequency"
  12.     ],
  13.     "title": "Association spreadsheet",
  14.     "name": "association_spreadsheet",
  15.     "type": "object",
  16.     "properties": {
  17.         "study_tag": {
  18.             "description": "Linking associations with study. Must match the study tag in the study table",
  19.             "type": "string",
  20.             "user_friendly": "Study tag"
  21.         },
  22.         "haplotype_id": {
  23.             "description": "For haplotype associations identifies identifies rows belonging together",
  24.             "type": "string",
  25.             "user_friendly": "Haplotype ID"
  26.         },
  27.         "variant_id": {
  28.             "description": "rsID or other variant identifier",
  29.             "type": "string",
  30.             "user_friendly": "Variant ID"
  31.         },
  32.         "pvalue": {
  33.             "description": "Reported p-value for variant in scientific notation",
  34.             "type": "string",
  35.             "user_friendly": "p-value",
  36.             "minimum": 0.0,
  37.             "maximum": 1e-05
  38.         },
  39.         "pvalue_text": {
  40.             "description": "Free text to add extra information eg. conditional analysis",
  41.             "type": "string",
  42.             "user_friendly": "Extra information"
  43.         },
  44.         "proxy_variant": {
  45.             "description": "rsID of a proxy SNP used in the replication stage only",
  46.             "type": "string",
  47.             "user_friendly": "Proxy variant"
  48.         },
  49.         "effect_allele": {
  50.             "description": "The allele whose effects are being studied in relation to the phenotype",
  51.             "type": "string",
  52.             "user_friendly": "Effect allele",
  53.             "pattern": "^[actgACTG]*$"
  54.         },
  55.         "other_allele": {
  56.             "description": "The other allele at the locus",
  57.             "type": "string",
  58.             "user_friendly": "Other allele",
  59.             "pattern": "^[actgACTG]*$"
  60.         },
  61.         "effect_allele_frequency": {
  62.             "description": "frequency of the effect allele or haplotype in the control population",
  63.             "type": "number",
  64.             "user_friendly": "Effect allele frequency"
  65.         },
  66.         "odds_ratio": {
  67.             "description": "Effect size of the effect allele or haplotype from a logistic regression for binary traits",
  68.             "type": "number",
  69.             "user_friendly": "Odds ratio"
  70.         },
  71.         "beta": {
  72.             "description": "Effect size from a linear regression for continious traits",
  73.             "type": "number",
  74.             "user_friendly": "Beta"
  75.         },
  76.         "beta_unit": {
  77.             "description": "Beta unit",
  78.             "type": "string",
  79.             "user_friendly": "Beta unit"
  80.         },
  81.         "ci_lower": {
  82.             "description": "Lower limit of the confidence interval",
  83.             "type": "number",
  84.             "user_friendly": "CI lower"
  85.         },
  86.         "ci_upper": {
  87.             "description": "Upper limit of the confidence interval",
  88.             "type": "number",
  89.             "user_friendly": "CI upper"
  90.         },
  91.         "standard_error": {
  92.             "description": "standard error of the effect",
  93.             "type": "number",
  94.             "user_friendly": "Standard error"
  95.         }
  96.     }
  97. }
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