$product_view = views_get_view('view_name');
  $product_view->set_display('page_1');
  $pager = array(
    'type' => 'some',
    'options' => array(
      'offset' => 0,
      'items_per_page' => 12,
    ),
  );

  if ($count != NULL) {
    $pager['items_per_page'] = $count;
  }

  $product_view->display_handler->set_option('pager', $pager);
      $product_view->display_handler->set_option('pager', $pager);

      $product_view->set_arguments([
        'abc' => TRUE,
        'xyz' => 123,
      ]);

      $product_view->some_property = $some_array;
      $product_view->execute();
      $list = $product_view->result;

function my_module_views_query_alter(&$view, &$query) {
  $view_args = $view->args;
  if (isset($view_args['abc']) && $view_args['abc']) {
    $some_property = $view->some_property ;
    $some_property[] = $view_args['xyz'];
    $query->add_where(1, 'node.nid', $some_property , 'NOT IN');
  }
}