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- After an Edmond man claimed a dewormer medication meant for dogs cured him of small-cell lung cancer, some cancer researchers now want to learn more about the mysterious drug that is piquing patient interest.
- Joe Tippens was only given three months to live. But doctors later enrolled him in a clinical trial they hoped could give him more time.
- Tippens said he received a tip from a veterinarian who suggested he try a dog dewormer drug called fenbendazole, which was believed to display cancer-fighting properties, according to cell studies.
- In his blog, Tippens wrote that after receiving his fourth cancer-free diagnosis at the University of Texas MD Anderson Cancer Center in Houston last April, the results indicated that his cancer was gone after two years of treatment.
- Dr. Stephen Prescott, Oklahoma Medical Research Foundation president, said Tippens’ story interested him after speaking to a scientist at Johns Hopkins University who conducted a case study where scientists implanted immune-deficient mice with human tumors.
- While the experiment was still in progress, a veterinarian at Johns Hopkins University put the mice on the same deworming medications that Tippens used.
- After examining the results, scientists found that the implanted tumors would not grow, he said.
- “They were trying to make cancer in mice and unbeknownst to them, something that the veterinarian in the facility had done prevented that,” Prescott said.
- Shortly after, Prescott said he met Tippens through mutual friends.
- While director of the Huntsman Cancer Institute in Salt Lake City, Prescott said he “would hear stories all the time about new approaches to cancer medical treatments,” but remained skeptical.
- However, Prescott said he and a team Tippens is putting together will collaborate to explore alternative care methods.
- “It would be a wonderful thing if we discovered that there is this compound that has broad activity with dramatic responses like with Mr. Tippens, what a great thing that would be,” he said.
- Prescott said they plan to spend six to 12 months researching the medical records of cancer patients.
- In their study, they will consider specifics such as the treatment they received, how they reacted and how long they were given to live.
- By studying Tippens’ case further, Prescott said they could provide more truth to the dog dewormer medicinal impact.
- One problem made evident by some anticancer medications is that over time they become ineffective, he said.
- It is the reason why patients today are seeking other treatments.
- Most anticancer drugs attack a specific target on or in the cancer cell, he explained.
- “What often happens is that it works initially and then quits working,” Prescott said.
- “And the reason is the cancer has continued to change and have additional mutations, so what was the initial targets no longer respond to the drug.”
- Part of Tippens’ treatment regimen was CBD.
- Chip Paul, the founder of Owasso-based GnuPharma, a company that specializes in developing natural products, said he is unsure how influential CBD alone was on Tippens’ cancer cells.
- “If he was just taking cannabidiol, it is doubtful that it affected his cancer because it does not have the right actives in it to be able to signal that,” Paul said.
- Prescott said as the clinical trial develops, he hopes that it will eventually lead to answers regarding Tippens’ shocking recovery.
- “I do really applaud Mr. Tippens for his forthrightness and aggressive stance for something he believes has helped him and can help us as a people,” Prescott said.
- “He has done more than any patient has done in that regard.”
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