<div id="content">
       <div id="blocks-container">
             <div id="left-block">
                    //In here load the slider block and display in here
             </div>
              <div id="right-block">
                     <div>
                    //In here load the top right  block and display in here
                     </div>
                     <div>
                     //In here load the bottom right  block and display in here
                     </div>
             </div>
       </div>
</div>

#content{
       text-align:center;
       width:100%;
       height:auto;
       display:inline-block;
}
#blocks-container{
       margin:auto;
       width: 975px;
       height:auto;
       display:inline-block;
}
#left-block{
       float:left;
       width: 760px;
}
#right-block{
       float:right;
       width: 215px;
}
#right-block > div{
       clear:both;
       width: 100%;
      float:left;
}