string SqlQry = "SELECT [Name] FROM [Table] WHERE [Column 2] = @1 OR [Column 3] = @2 OR [Column 4] = @3 AND [Region] = @4 AND [Type] = @5 ORDER BY [Name] ASC";

                cmd.Parameters.AddWithValue("@1", Combobox1.SelectedItem);
                cmd.Parameters.AddWithValue("@2", Combobox1.SelectedItem);
                cmd.Parameters.AddWithValue("@3", Combobox1.SelectedItem);
                cmd.Parameters.AddWithValue("@4", "Italy");
                cmd.Parameters.AddWithValue("@5", "Bus");