documentclass{article}
usepackage{xcolor,colortbl}

definecolor{lblue}{RGB}{218,227,254}
newcommand{lblue}{cellcolor{teal}}

begin{tabular}{|c|c|}
hline
lblue yes & no \
hline
end{tabular}

definecolor{newcolor}{RGB}{200,100,50}
newcommand{newcolor}{cellcolor{teal}}

documentclass{article}
usepackage{xcolor,colortbl}

definecolor{lblue}{RGB}{218,227,254}
newcommand{lblue}{cellcolor{teal}}
definecolor{newcolor}{RGB}{200,100,50}
newcommand{newcolor}{cellcolor{newcolor}}

begin{document}
begin{tabular}{|c|c|}
hline
lblue yes &newcolor no \
hline
end{tabular}

end{document}