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- Anti-Early Pregnancy / Abortifacient powder Mifepristone CAS 84371-65-3
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- Mifepristone Basic information
- Product Name:Mifepristone
- Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;17-beta)-(11-bet;17beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-(11bet;17-beta-hydroxy-11-beta-(4-dimethylaminophenyl-1)-17-alpha-(prop-1-ynyl)oest;-17beta-ol-3-one;4,9-dien-3-one;r38486
- CAS: 84371-65-3
- MF: C29H35NO2
- MW: 429.59
- EINECS:
- Product Categories: Steroids;Hormone;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Nuclear Receptors;Steroid and Hormone;API;Hormone Drugs
- Instructions
- Oral administration has anti-pregnancy effect, currently applied for people with pregnancy <49 days. Specific usage in three:
- The first usage: orally administration of 600 mg mifepristone in single dose, place 1mg PGF2α (Kaposi prostaglandin) or PGO5 (Kaposi prostaglandin methyl ester) at the vaginal fornix at third or fourth day with the complete abortion rate being as high as 92.3 %. Currently Mifepristone dose has been reduced to a single dose of 200mg, or divided doses of 125-150mg with clinical results not being affected.
- The second usage: oral administration of single dose of 600 mg; apply intramuscular injection 0.25 mg of a single oral dose; at 36-48 hours after oral administration, apply intramuscular injection 0.25 mg, or 0.375 mg or 0.5 mg of sulprostone with complete abortion rate of 96%; with the larger amount of sulprostone applied, the sooner the embryonic will be discharged.
- The third usage: apply a single oral-administrated dose of 600mg; at 48 hours after oral administration, place 1 mg of ONO802 (gemeprost) pessary suppository inside of the vagina with the complete abortion rate being 95%.
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