file = 'C:\Exe\First Version\filename.exe'
os.system(file)

file = 'C:\Exe\First Version\filename.exe'
os.system('"' + file + '"')

import subprocess
file = 'C:\Exe\First Version\filename.exe'
subprocess.call([file])

file = '"C:\Exe\First Version\filename.exe"'
os.system(file)

file = 'C:\Exe\FirstV~1\filename.exe'
os.system(file)

import subprocess, shlex
mycmd='"C:\Program Files\7-Zip\7z" x "D:\my archive.7z" -o"D:\extract folder" -aou'
subprocess.run(shlex.split(mycmd))