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Puberty Blocker Research - Formal Citations

veil27
Jan 25th, 2022 (edited)
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  1. Sources Cited:
  2. (By order the source was represented in.)
  3.  
  4. 1. Washington Post, Rand Paul questions Rachel Levine on gender-affirming care for minors
  5. https://www.youtube.com/watch?v=Krf0Cm-FKro&ab_channel=WashingtonPost
  6.  
  7. 2. Kumar, Pratap, and Alok Sharma. “Gonadotropin-releasing hormone analogs: Understanding advantages and limitations.” Journal of human reproductive sciences vol. 7,3 (2014): 170-4. doi:10.4103/0974-1208.142476
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229791/#sec1-1title
  9. (This article aided in explaining the functions of GnRH-agonists in the brain.)
  10.  
  11. 3. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. “Gonadotropin Releasing Hormone (GnRH) Analogues.” [Updated 2018 Mar 20]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK547863/ (This article aided in providing insight towards the functionalities of GnRH analogues, and the potential short-term and long-term side effects of GnRH-agonists. This article also recognizes GnRH-agonists are considered off-label for gender dysphoria, CPP, and fertility.)
  12.  
  13. 4. Editor(s): Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, Henry M. Kronenberg,
  14. Williams Textbook of Endocrinology (Thirteenth Edition),
  15. Elsevier, 2016, Pages 1855-1916, ISBN 9780323297387,
  16. https://doi.org/10.1016/B978-0-323-29738-7.00044-7. - (https://www.sciencedirect.com/science/article/pii/B9780323297387000241), (https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/gnrh-agonists) (This chapter aided in providing insight towards the usages of GnRH-agonists in treating ISS, and the side effects that were observed from youth undergoing puberty blockers.)
  17.  
  18. 5. Lee PA, Houk CP. Gonadotropin-releasing hormone analog therapy for central precocious puberty and other childhood disorders affecting growth and puberty. Treat Endocrinol. 2006;5(5):287-96. doi: 10.2165/00024677-200605050-00003. PMID: 17002488. (This study aided in providing insight towards the usages of GnRH-agonists in treating CPP, mentions the lack of benefits GnRH analogues present when intended to treat individuals with these conditions.)
  19.  
  20. 6. Boepple PA, Mansfield MJ, Wierman ME, Rudlin CR, Bode HH, Crigler JF Jr, Crawford JD, Crowley WF Jr. Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty. Endocr Rev. 1986 Feb;7(1):24-33. doi: 10.1210/edrv-7-1-24. PMID: 2937629.
  21. https://pubmed.ncbi.nlm.nih.gov/2937629/
  22. (This study delves into the effectiveness of GnRH-agonists on predicted outcome of final height for patients contending with CPP, and other related conditions that indicate puberty blocker treatment.)
  23.  
  24. 7. R.C.L. Page, 43 - Miscellaneous hormones,
  25. Editor(s): J.K. Aronson,
  26. Side Effects of Drugs Annual,
  27. Elsevier, Volume 32, 2010, Pages 789-802, ISSN 0378-6080, ISBN 9780444535504,
  28. https://doi.org/10.1016/S0378-6080(10)32043-5.
  29. (https://www.sciencedirect.com/science/article/pii/S0378608010320435) (This chapter aided in providing insight towards the bone health of both children and adults who undergo long-term usage of GnRH-agonists.)
  30.  
  31. 8. Vasileios Chortis, Kristien Boelaert,
  32. Chapter 42 - Miscellaneous Hormones, Editor(s): Sidhartha D. Ray,
  33. Side Effects of Drugs Annual,
  34. Elsevier, Volume 37, 2015, Pages 539-558, ISSN 0378-6080, ISBN 9780444635259,
  35. https://doi.org/10.1016/bs.seda.2015.07.004.
  36. (https://www.sciencedirect.com/science/article/pii/S0378608015000288), (https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/gnrh-agonists) (This chapter aided in providing insight towards the usages of GnRH-agonists in treating CPP, and the side effects that were observed from youth undergoing puberty blockers.)
  37.  
  38. 9. Cappa M, Cianfarani S, Ghizzoni L, Loche S, Maghnie M (eds): Advanced Therapies in Pediatric Endocrinology and Diabetology. Endocr Dev. Basel, Karger, 2016, vol 30, pp 54-59. doi: 10.1159/000439330
  39. https://www.karger.com/Article/Abstract/439330# (This article aided in providing insight towards the commonalities of fractures during exportation of Histrelin implants.)
  40.  
  41. 10. Davis JS, Alkhoury F, Burnweit C. Surgical and anesthetic considerations in histrelin capsule implantation for the treatment of precocious puberty. J Pediatr Surg. 2014 May;49(5):807-10. doi: 10.1016/j.jpedsurg.2014.02.067. Epub 2014 Feb 22. PMID: 24851775.
  42. https://pubmed.ncbi.nlm.nih.gov/24851775/
  43. (This study addressed the surgical and anesthetic considerations for Histrelin implantation, and difficulties with routinely extracting the implant, among other associated complications.)
  44.  
  45. 11. Eugster EA. Experience with the Histrelin Implant in Pediatric Patients. Endocr Dev. 2016;30:54-9. doi: 10.1159/000439330. Epub 2015 Dec 10. PMID: 26683629. https://pubmed.ncbi.nlm.nih.gov/26683629/ (This study addressed the surgical and anesthetic considerations for Histrelin implantation, and difficulties with routinely extracting the implant, among other associated complications.)
  46.  
  47. 12. Mayo Foundation for Medical Education and Research. (2021, September 14). Pubertal blockers for transgender and gender-diverse youth. Mayo Clinic. Retrieved January 25, 2022, from https://www.mayoclinic.org/diseases-conditions/gender-dysphoria/in-depth/pubertal-blockers/art-20459075
  48. (This article and website was helpful in providing side effects of GnRH-agonists, and clinical efficacies around administering GnRH-agonists for transitioning youth.)
  49.  
  50. 13. Cunha, J. P. DO, FACOEP (2020, October 29). What is endometriosis? symptoms, causes, treatment. RxList. Retrieved January 25, 2022, from https://www.rxlist.com/endometriosis_slideshow_pictures/article.htm (This article and website was helpful in providing side effects of GnRH-agonists, specifically Lupron.)
  51.  
  52. 14. Novara G, Galfano A, Secco S, Ficarra V, Artibani W: Impact of Surgical and Medical Castration on Serum Testosterone Level in Prostate Cancer Patients. Urol Int 2009;82:249-255. doi: 10.1159/000209352
  53. https://www.karger.com/Article/Abstract/209352# (This study provided insight towards the usages and potential adversities GnRH-agonists are attributed for in treatment of prostatic cancer, this study is notable for reporting on the statistics of observed infertility of male patients who underwent treatment.)
  54.  
  55. 15. 2019. GnRH analogue injections. [ebook] Manchester, UK: NHS Manchester University, NHS Foundation Trust in accordance with St. Mary's Hospital Gynecological Sevices, pp.Pages 1-4. Available at:
  56. https://mft.nhs.uk/app/uploads/sites/4/2019/11/19-71-GnRH-analogue-injections-Nov-19.pdf
  57. (This article provided insight towards the usages and potential adversities GnRH-agonists are attributed for in treatment of female reproductive issues, this medical article is notable for reporting on the side effects GnRH-agonists have on the female reproductive system.)
  58.  
  59. (My apologies for the variance in citation format, citations were copied directly from the providing source.)
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