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CVM General

absurdists
Apr 5th, 2017
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  1. OVERVIEW
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  3. Cel-Sci Corp (NYST:CVM) is a biotech company that was founded in 1983 with the intent of researching and developing immunotherapy (http://www.cancer.net/navigating-cancer-care/how-cancer-treated/immunotherapy-and-vaccines/understanding-immunotherapy) treatments for various forms of cancer and other immunodeficiency disorders. (ie. AIDs, HPV, etc) It's also a hot /biz/ meme that's been shilled recently.
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  5. Of particular note is the company's Multikine immunotherapy, which promises to assist in the treatment of squamous cell carcinoma (https://en.wikipedia.org/wiki/Squamous_cell_carcinoma) of the head and neck (Multikine is in phase 3 of clinical trials for this purpose) as well as HPV induced Cervical Dysplasia and Anal Warts, although Multikine remains in phase 1 of clinical trials for all HPV-related treatment purposes.
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  8. COMPANY WEBSITE
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  11. http://www.cel-sci.com/index.html
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  14. NOTABLE EMPLOYEES
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  16.  
  17. Geert R. Kersten, Director and CEO
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  19. Biography: http://www.bloomberg.com/research/stocks/people/person.asp?personId=258748&privcapId=258746
  20. Fox Buisness Interview: video.foxbusiness.com/v/4761247378001/
  21. Miscellaneous Interviews: https://www.youtube.com/watch?v=1n7Ej9RETmg
  22. https://www.youtube.com/watch?v=68B-BcPu_qE
  23. https://www.youtube.com/watch?v=3b71HeUYd8Y
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  25. Eyal Talor
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  27. Biography: http://www.bloomberg.com/research/stocks/people/person.asp?personId=258760&privcapId=258746
  28. Research papers: https://www.researchgate.net/profile/Eyal_Talor/publications
  29. Interview: https://vimeo.com/151833021 (inspires much more confidence than the CEO tbh)
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  32. INSIDER TRADING
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  35. http://openinsider.com/screener?s=CVM&o=&pl=&ph=&ll=&lh=&fd=730&fdr=&td=0&tdr=&fdlyl=&fdlyh=&daysago=&xs=1&xa=1&xd=1&xg=1&excludeDerivRelated=1&vl=&vh=&ocl=&och=&sic1=-1&sicl=100&sich=9999&grp=0&nfl=&nfh=&nil=&nih=&nol=&noh=&v2l=&v2h=&oc2l=&oc2h=&sortcol=0&cnt=100&page=1
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  38. CLINICAL TRIALS
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  40. Safety Study of Multikine in the Treatment of Perianal Warts [TERMINATED, PHASE 1]: https://clinicaltrials.gov/ct2/show/NCT02115919
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  43. Efficacy and Safety Study of Leukocyte Interleukin,Injection (LI) to Treat Cancer of the Oral Cavity (IT-MATTERS) [RECRUITING PARTICIPANTS, PHASE 3, ESTIMATED COMPLETION DATE: December 2017]: https://clinicaltrials.gov/ct2/show/NCT01265849?term=CEL-SCI+Corporation&rank=1
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  45. -----
  46. Study of Leukocyte Interleukin, Injection for Treatment of Perianal Warts (PAW) [RECRUITING PARTICIPANTS, PHASE 1]: https://clinicaltrials.gov/ct2/show/NCT03038828?term=CEL-SCI+Corporation&rank=2
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  49. Info on phase 3 redesign, copy pasta speculation on possible reason for hold from rgt thread:
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  51. CelSci realized there was a flaw in their study design (not enough people would die from their cancer -> not enough autopsies to show shrunk tumors and shit.) They wanted to change the parameters to include more people, but any change in a study underway requires special approval, so the study got a partial hold while the FDA could evaluate if the given alteration would invalidate any of the scientific rigor or methodology.
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  53. tl;dr Some egghead fucked up because he forgot their medicine actually works.
  54.  
  55. http://www.cel-sci.com/multikine_phase_3_clinical_trial_design.html
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  58. FDA SHIT
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  61. FDA warning addressed to Cel-Sci CEO, relates to marketing: https://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/EnforcementActivitiesbyFDA/WarningLettersandNoticeofViolationLetterstoPharmaceuticalCompanies/UCM268686.pdf
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  64. SEC SHIT
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  66.  
  67. SEC Prospectus Report: https://www.sec.gov/Archives/edgar/data/725363/000135448816007579/cvm_424b5.htm
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