Comparison of sentences

import numpy as np
import matplotlib.pyplot as plt
import pandas as pd
import re
from scipy.spatial.distance import cosine as cos
import collections
l=[]
with open(r'Myfile.txt') as fl:
    l=fl.readlines()

data=pd.DataFrame()
for i in l:
    i=i.lower()
    sen=re.split('[^a-z]',i)
    ma= {}
    for j in sen:
        if len(j)>=2:
            if not ma.get(j):
                ma[j]=1
            else:
                ma[j]+=1
    data=data.append(ma, ignore_index=True)
data.fillna(0,inplace=True)
data=data.apply(np.intc)
res= [-1,-1]
x=[2,2]
for i in range(1,data.shape[0]):
    q=cos(data.iloc[0,:],data.iloc[i,:])
    if(q<=x[0]):
        x[1]=x[0]
        x[0]=q
        res[1]=res[0]
        res[0]=i
    elif q<x[1]:
        x[1]=q
        res[1]=i
print(res,l[0],l[6],l[4])