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***IMPORTANT NOTE: This guide assumes you know how to beat the game normally. It is extremely difficult to follow a speedrunning guide if you haven't beaten the game or watched others beat it. If you don't know the basic steps for beating the game, such as how to reach the Elite Four, I recommend learning this before doing runs.***
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***IMPORTANT NOTE: This guide assumes basic knowledge of the game, including the map and hidden item locations.  If you are unfamiliar, the current WR video is helpful***
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Nidoran manip: https://www.youtube.com/watch?v=qPzSWHyMuW8
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4-
Moon manip: https://pastebin.com/jnj9j47S
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5-
Cans manip: https://www.youtube.com/watch?v=AqY-8Wa2q_4
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(OPTIONAL) Advanced Nidoran manip (extend to catch Pidgey and no forest encounters): https://pastebin.com/ApTUFBQ3
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(OPTIONAL) Advanced Moon manip (save in Route 3 grass): https://pastebin.com/tggXpQRC
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8-
HP-dependent strats: https://pastebin.com/cK1UCF8y
8+
9
10
PALLET TOWN 
11
- Choose Squirtle, and give it a 1-character name 
12
- Rival battle: Tail Whip once, then spam Tackle (use a second Tail Whip if you get Growled turn 1) 
13
14
ROUTE 1 
15
- Kill a Lv. 2-3 Rattata or Lv. 2-3 Pidgey using Tackle. You need the experience to get Bubble for Brock 
16
- When walking down to deliver Oak's Parcel, cut through the second-to-last patch of grass if you haven't yet fought an encounter 
17
18
PALLET TOWN 
19
- When delivering the parcel, walk behind Prof. Oak so your rival takes fewer steps in the cutscene 
20
21
VIRIDIAN CITY 
22
- Buy 6 Poke Balls
23
- After exiting the mart, save and hard reset on this tile: http://pokeworld.herokuapp.com/rb/1#67,182
24
	> On emulator, hard reset using a hotkey
25
	> On console, hard reset by pressing the reset button (or turning the console off and on)
26
- RNG manipulate a Lv. 4 Nidoran encounter by replicating the inputs in this video: https://www.youtube.com/watch?v=qPzSWHyMuW8
27
	> The manip has a 1/60 chance to produce a Lv. 4 Rattata on the desired tile
28
	> The manip has a 1/60 chance to produce no encounter on the desired tile
29
	> The manip has a 1/60 chance to produce an unrunnable Nidoran (17 HP instead of 18 at Lv. 4)
30
	> The manip has a 1/60 chance to produce a slightly worse, but still runnable, Nidoran (13 Defense instead of 14 at Lv. 8)
31
	> The manip has a 2/60 chance to produce a Nidoran that does not get in the ball with perfectly executed inputs
32
	> If the Nidoran breaks out, or you're not confident in throwing the ball perfectly, Tackle it twice before throwing a ball
33
	> If the manip fails, you might have gotten one of the 1/60 chances, aka IGT0s. Re-save to get a new chance
34
	> Give the Nidoran a 1-character name
35
	> A faster, more difficult manip can be found here: https://www.youtube.com/watch?v=6iOx592-xhU
36
- Get the hidden tree Potion: http://pokeworld.herokuapp.com/rb/1#54,166
37
38
VIRIDIAN FOREST
39
- Follow this path (only red tiles can produce encounters): http://i.imgur.com/3o7klcA.png
40
- Get the Antidote: http://pokeworld.herokuapp.com/rb/51#25,11
41
- Get the hidden Potion: http://pokeworld.herokuapp.com/rb/51#1,18
42
- Heal to 10+ HP for Weedle Guy
43
- Weedle Guy: Tail Whip x2, Tackle x4-6. If you get poisoned, wait until after the fight to use the Antidote. If you fall below 7 HP, use a Potion
44
- After the fight: 
45
	> Switch Nidoran to the front 
46
	> Heal to 17+ HP 
47
	> Heal poison if necessary 
48
49
PEWTER GYM
50
- Save before Brock
51
- Brock: 
52
	> Immediately switch to Squirtle 
53
	> Geodude: Bubble x2-3
54
	> Switch to Nidoran after killing Geodude, then immediately switch to Squirtle
55
	> Onix: Bubble x2-3. If Onix uses Bide on the turn you switch to Squirtle, use Tail Whip twice, then Bubble 
56
	> Onix does 6 damage with Tackle
57
58
PEWTER CITY
59
- Go the mart
60
- Change the battle style option from SHIFT to SET
61
- Buy 8 Potions
62
63
ROUTE 3 
64
- You need to use one fewer Horn Attack than what's listed below, so finish enemies with Tackle when it will kill 
65
- Bug Catcher 1: Leer+Horn Attack+Horn Attack on all three 
66
- Heal to full and save before the Youngster (aka Shorts Guy)
67
- Shorts Guy: Leer+HA+HA on both 
68
	> Quick Attack does 8-10 (13-16 critical, or after a Tail Whip)
69
	> Wrap does 3 (4 critical, or after a Tail Whip)
70
- Fight the Bug Catcher below, not the Lass above 
71
- Bug Catcher 2: HA+HA, HA+HA+HA, HA+HA, HA+HA+HA
72
- Bug Catcher 3: HA+HA, HA+HA+HA+HA 
73
- Catch a Spearow or a Pidgey in the grass patch ahead. Use Poison Sting to weaken Lv. 5 Spearows, Horn Attack to weaken Lv. 8 Pidgeys and Tackle to weaken everything else 
74
- Take the center before Mt. Moon
75
	> You can skip this with 3+ Horn Attacks, but you have to use Potions to heal, and the Moon fights are a bit tougher
76
77
MT. MOON
78
- As soon as you enter Mt. Moon, save and hard reset
79
- RNG manipulate a Paras encounter by replicating the inputs in this video: https://www.youtube.com/watch?v=zITeWzAheto
80
	> This manip has a 4/60 chance to produce a bad early encounter (meaning you won't get the Paras)
81
	> The manip has a 1/60 chance to produce an early Paras (you should weaken this one, since you won't get the normal one)
82
	> The manip has a 1/60 chance to produce a Paras on the desired tile that does not get in the ball with perfectly executed inputs
83
	> If the Paras breaks out, or you're not confident in throwing the ball perfectly, Poison Sting it once before throwing a ball
84
	> This manip requires a lot of practice. You can do runs without it while learning, but you'll eventually want to attempt it
85
	> If the manip fails, it might have been due to RNG. You can either continue as normal and perform a backup Paras manip at the end of Mt. Moon, or re-save to get a new chance
86
- Rocket: HA+HA(+PS), HA+HA(+HA)
87
	> Zubat does 6-8 with Leech Life (10-12 after 1 Tail Whip). Consider healing or switching if you're at low HP or confused
88
- One tile before the Super Nerd:
89
	> Use the Rare Candy to reach L16 and evolve
90
	> Teach Water Gun over Tackle
91
	> Use the Moon Stone
92
	> Teach Mega Punch over Leer
93
- Super Nerd: HA+HA, MP(+PS), MP+HA
94
- Choose the Helix Fossil
95
- If you don't have a Paras, use this backup manip: https://www.youtube.com/watch?v=29TwUgeeGME
96
	> This Paras does not get in the ball with perfect inputs, so you should Horn Attack it first
97
98
CERULEAN CITY 
99
- Take the center
100
- Go to the bike shop, talk to the guy, and mash B to get instant text
101
	> NOTE: You will lose instant text whenever you open a menu. Try to avoid healing or switching before Bill's house
102
- Get the hidden Rare Candy: http://pokeworld.herokuapp.com/rb/1#235,44
103
104
NUGGET BRIDGE 
105
- Rival: HA+HA+HA, HA, MP, MP+HA 
106
- Bug Catcher: MP x2
107
- Lass: MP(+PS), HA+HA
108
- Heal to 12+ HP
109
- Youngster: MP x3
110
- Lass: MP(+PS), HA+HA
111
- Heal to 15+ HP 
112
- Jr. Trainer: HA+PS
113
- Rocket: MP x2 (HA the Zubat if you have <7 Mega Punch PP)
114
115
ROUTE 25
116
- Bottom Hiker: WG
117
- Lass: MP, HA+HA 
118
- Bottom Hiker: WG x2, MP(+HA), WG 
119
- Lass: MP, HA, MP (HA Oddishes with 0-2 Mega Punch PP)
120
	> Learn Thrash over Water Gun
121
- Get the hidden Ether: http://pokeworld.herokuapp.com/rb/1#288,3
122
- Say yes to Bill (you'll lose instant text here)
123
- After the Bill cutscene:
124
	> Heal to full
125
	> Candy to L24
126
	> Escape Rope back to Cerulean
127
128
CERULEAN CITY
129
- Get instant text from the bike shop again
130
- Walk through the Dig house to fight the Rocket (Thrash x2-4)
131
- Hop the ledge and enter the gym
132
133
CERULEAN GYM
134
- Jr. Trainer: Thrash+Thrash
135
- Misty: Thrash, Thrash+Thrash(+Thrash)
136
	> If you get confused, sacrifice your flier (if flier is dead, sacrifice Paras)
137
138
CERULEAN CITY
139
- If you have <16 HP:
140
	> Potion once
141
	> Get instant text again (also do this if you lost IT in the gym)
142
- Walk through the Dig house again, and continue south toward Vermilion
143
144
ROUTE 5 
145
- Enter the building in the southeast corner, and take the stairs to the underground path 
146
- Get the hidden Full Restore: http://pokeworld.herokuapp.com/rb/119#3,4
147
148
ROUTE 6 
149
- Walk through the left grass to avoid the Bug Catcher on the right 
150
- Jr. Trainer-F: Thrash x3 
151
- Heal to 3+ HP
152
- Jr. Trainer-M: Thrash x2
153
154
VERMILION CITY 
155
- Go to the S.S. Anne
156
157
S.S. ANNE
158
- Heal to 17+ HP
159
- Take the left stairs, then go down and right to meet your rival
160
- Rival: HA+HA, MP, Thrash, Thrash+Thrash. If you get Sand-Attacked, sacrifice your weakest slave
161
- Get HM01 from the captain, then leave and head to the gym 
162
163
VERMILION CITY
164
- Go to the mart (you'll lose instant text here)
165
- Sell all Poke Balls and the Nugget. Also sell TM34 if you have your Antidote 
166
- Buy 3 Repels
167
- On the tile before the Cut bush: 
168
	> Heal to 25+ HP
169
	> Teach TM11 (Bubblebeam) over Poison Sting
170
	> Swap your slot 1 item with Repels 
171
	> Teach HM01 (Cut) to Paras
172
	> Teach TM28 (Dig) to Paras
173
	> Cut the bush 
174
- Save and hard reset on this tile: http://pokeworld.herokuapp.com/rb/1#235,199
175
- RNG manipulate the trash cans puzzle by replicating the inputs in this video: https://www.youtube.com/watch?v=AqY-8Wa2q_4
176
	> The manip has a 3/60 chance to fail
177
	> You don't need to be frame perfect after talking to the first can
178
	> If the manip fails, use this guide to solve the puzzle normally: http://i.imgur.com/mCgVe4w.png
179
180
VERMILION GYM
181
- Surge: HA+BB, Thrash, Thrash+Thrash
182
183
VERMILION CITY 
184
- Go to the house above the gym, talk to the chair of the fan club to get the Bike Voucher, then Dig back to Cerulean 
185
186
CERULEAN CITY 
187
- Get the Bicycle from the bike shop 
188
- After leaving the shop: 
189
	> Swap your slot 2 item with the Bicycle 
190
	> Teach TM24 (Thunderbolt) over Horn Attack
191
	> Get on the bike and head east to Route 9, cutting the two bushes in your way 
192
193
ROUTE 9 
194
- Jr. Trainer: MP, Thrash x3
195
	> If you get paralyzed, use your Full Restore after the fight (not during)
196
- Bug Catcher: BB, Thrash x2-3
197
198
ROCK TUNNEL
199
- Map: http://wiki.pokemonspeedruns.com/index.php/Pok%C3%A9mon_Red/Blue/Rock_Tunnel
200
- Use a Repel one step after entering
201
- Pokemaniac 1: BB, TB 
202
- Pokemaniac 2: TB 
203
- Heal to 6+ HP; save if below 20 HP
204
- Jr. Trainer: Thrash x2-4. If you get paralyzed, use your Full Restore 
205
- Use your second Repel somewhere near the yellow tile on the map above 
206
- Use your third Repel on the blue/yellow tile immediately before the Hiker 
207
- Hiker: BB x3 
208
- Jr. Trainer: Thrash x3 
209
	> Pidgey does 5 with Quick Attack
210
- After exiting, head south to Lavender Town and west to Route 8 
211
212
ROUTE 8 
213
- Gambler: BB(+Thrash), Thrash
214
	> Vulpix does 4 with Quick Attack
215
- Take the underground path to Celadon City 
216
- Pick up the hidden Elixer in the underground: http://pokeworld.herokuapp.com/rb/121#21,5
217
218
CELADON CITY 
219
- Bike to the mart 
220
	> 2F: Buy TM07, then buy 3 Super Potions and 10 Super Repels 
221
	> 4F: Buy 1 Poke Doll 
222
	> 6F: Buy 1 Soda Pop. Give it to the girl for TM48, then buy 1 more Fresh Water 
223
	> 5F: Buy 11 X Accuracy, 2 X Special and 5 X Speed
224
	> Take the elevator to 1F, then leave 
225
- Bike west, cut the bush, then go through the building and get HM02 from the girl in the house 
226
- Upon exiting the house: 
227
	> Swap your slot 2 item with Super Repels 
228
	> Teach TM48 (Rock Slide) over Mega Punch
229
	> Use a Super Repel 
230
	> Swap your slot 3 item with X Accuracies 
231
	> Teach HM02 (Fly) to your flier 
232
	> Fly to Lavender, and walk to the tower 
233
234
LAVENDER TOWER 
235
- Rival: TB x2, BB, Thrash, Thrash+Thrash
236
	> Ivysaur does 10-12 with Vine Whip
237
- Channeler (4F): Rock Slide x2 
238
- Get the Elixer item ball: http://pokeworld.herokuapp.com/rb/145#12,10
239
- Get the hidden Elixer: http://pokeworld.herokuapp.com/rb/146#4,12
240
- Take the free heal on 5F 
241
- Channeler (6F): Rock Slide
242
- Channeler (6F): Rock Slide 
243
- Teach TM07 (Horn Drill) over Rock Slide
244
- Get the Rare Candy that blocks the way, then enter the Ghost battle and escape using the Poke Doll
245
- Rocket 1: TB x3
246
- Rocket 2: X Acc, Drill x2 
247
- Rocket 3: TB x2, Thrash x2-3
248
- Talk to Mr. Fuji to warp to his house 
249
250
LAVENDER TOWN 
251
- Talk to Mr. Fuji again to get the Poke Flute, then walk out and Fly to Celadon City 
252
253
CELADON CITY 
254
- Take the center, then bike to Silph Co.
255
256
SILPH CO.
257
- Take the stairs to 5F
258
- Get the Elixer in the tree: http://pokeworld.herokuapp.com/rb/210#12,3
259
- Walk down and talk to the Rocket
260
- Rocket: Thrash+Thrash(+Thrash)
261
- Take the teleporter to 9F, then take it back to 5F
262
- Get the Card Key: http://pokeworld.herokuapp.com/rb/210#21,16
263
- Use your Full Restore if paralyzed
264
- Take the teleporter to 9F, then take it back to 5F, then open the door to your left 
265
- Take the teleporter to 3F 
266
- Walk right, then up, then open the door to your left, and take the teleporter to 7F 
267
- Once on 7F, walk one step up, then left to meet your rival 
268
- Silph Rival: X Acc, X Speed, Drill x5
269
- Use an Elixer
270
- Take the teleporter to 11F
271
- Rocket: X Acc, BB, Drill x2
272
- Giovanni: X Acc, Drill x2, BB, Drill
273
- Backtrack to 3F, then take the elevator to 10F
274
- Get TM26: http://pokeworld.herokuapp.com/rb/234#2,12
275
- Get the Rare Candy: http://pokeworld.herokuapp.com/rb/234#4,14
276
- Dig out
277
278
CELADON CITY
279
- Bike west
280
- On the tile before the Snorlax:
281
	> Use a Super Repel
282
	> Swap your slot 5 item with X Speeds
283
	> Use the Poke Flute 
284
- Run from the Snorlax 
285
286
CYCLING ROAD
287
- Get the hidden Rare Candy: http://pokeworld.herokuapp.com/rb/1#125,148
288
- Get the hidden PP Up: http://pokeworld.herokuapp.com/rb/1#127,206
289
- After exiting the building:
290
	> Teach TM26 (Earthquake) over Thrash
291
	> Use the PP Up on Horn Drill
292
	> Bike to the Safari Zone
293
294
SAFARI ZONE
295
- Map: http://i.imgur.com/oBebL5z.jpg
296
- Upon entering, Super Repel and get on the bike
297
- Get the Full Restore: http://pokeworld.herokuapp.com/rb/217#21,10
298
- Use another Super Repel around this tile: http://pokeworld.herokuapp.com/rb/218#28,7
299
- Get the Gold Teeth: http://pokeworld.herokuapp.com/rb/219#19,7
300
- Get HM03 from the guy in the house, then walk outside and Dig back to Celadon
301
302
CELADON CITY
303
- Fly to Fuchsia, then bike to the gym
304
305
FUCHSIA GYM 
306
- Walk as far right as you can, then up, then talk to the Juggler that faces right 
307
- Juggler 1: EQ x4 
308
- Heal to 47+ HP (but ideally no higher than 80)
309
- Hug the east wall, then the north wall, then walk down into the Juggler's vision
310
- Juggler 2: EQ, EQ+TB 
311
- Koga: EQ x3, then use an Elixer on Weezing
312
	> If Koga uses an X Attack, stall with X Accuracy (TB if he X Attacks again)
313
	> The goal is to die to Selfdestruct, but it's OK if you don't
314
315
FUCHSIA CITY 
316
- After exiting the gym:
317
	> Use a Super Repel
318
	> Swap your slot 6 item with X Specials
319
	> Teach HM03 (Surf) to Squirtle
320
	> Use 3 Rare Candies to reach Lv. 43 (and revive Nidoking into red bar)
321
	> Bike east to the warden's house
322
- Get HM04 from the warden, then Fly to Pallet Town 
323
324
PALLET TOWN 
325
- Walk to the water, and Surf south to Cinnabar Mansion 
326
327
CINNABAR MANSION 
328
- Use a Super Repel a few steps after entering
329
- Head straight up and take the stairs 
330
- On the next floor, go right five steps, then go up and take the stairs 
331
- On the next floor, go down to activate the switch, then continue down to fall through the hole 
332
- After falling, go left and down to dodge the Scientist, then take the stairs to the right 
333
- Get TM14: http://pokeworld.herokuapp.com/rb/216#19,25
334
- Activate the switch to the left, then follow the path to the northeast corner to activate the second switch 
335
- Teach HM04 to Squirtle (over Tackle) and TM14 (Blizzard) to Nidoking (over Bubblebeam)
336
- Get the Secret Key: http://pokeworld.herokuapp.com/rb/216#5,13
337
- Dig out, then bike to the Celadon Gym
338
339
CELADON GYM
340
- Hug the left wall, then cut the bush in the top-left corner 
341
- Beauty: Blizzard (use Poke Flute if put to sleep)
342
- Erika: EQ, Blizzard, EQ
343
- Walk out, then Fly to Cinnabar and bike to the gym
344
345
CINNABAR GYM
346
- Questions: ABBBAB 
347
- Blaine: X Acc, EQ, Drill x3 (Drill Growlithe if Blaine uses a Super Potion)
348
- Dig out, then bike to the Saffron Gym
349
350
SAFFRON GYM 
351
- Teleporters: top-left, bottom-left, bottom-left 
352
- Sabrina: EQ x4
353
- Dig out, then Fly to Viridian and bike to the gym
354
355
VIRIDIAN GYM 
356
- Go left 2 tiles, then up to fight the first required trainer 
357
- Cooltrainer: EQ 
358
- Continue left, then save before the next fight 
359
- Blackbelt: X Acc, Drill, Blizzard, Drill
360
- Exit and re-enter the gym to reset Blackbelt's position and clear the path to Giovanni 
361
- Use an Elixer
362
- Giovanni: EQ x4, Blizzard(+Blizzard)
363
364
VIRIDIAN CITY 
365
- Use a Super Repel, then bike west to Route 22 
366
367
ROUTE 22
368
- Rival: X Acc, X Speed, Blizzard(+Blizzard), Blizzard, TB, EQ x2, Drill
369
- Bike to Route 23
370
371
ROUTE 23
372
- Bike to the water
373
- After exiting the water, use another Super Repel and bike to Victory Road
374
375
VICTORY ROAD
376
- Maps:
377
	> 1F: http://cdn.bulbagarden.net/upload/5/56/Victory_Road_1F_RBY.png
378
	> 2F: http://cdn.bulbagarden.net/upload/1/11/Victory_Road_2F_RBY.png
379
	> 3F: http://cdn.bulbagarden.net/upload/e/e5/Victory_Road_3F_RBY.png
380
- Use Strength upon entering 
381
- Push the boulder on the left onto the switch on the right, then bike to the ladder in the top-left corner 
382
- On the next floor: 
383
	> Use Strength again 
384
	> Push the boulder below onto the switch 
385
	> Bike up the steps so you're hugging the north edge, then use a Super Repel 
386
	> Bike right, then down the steps, then right and up to the ladder 
387
- On the next floor: 
388
	> Use Strength again 
389
	> Push the boulder up 2 tiles, left a bunch, then onto the switch 
390
	> Bike to the boulder in the bottom-right corner, push it down the hole, then go down the hole 
391
- Use Strength one last time, use your last Super Repel, then get on your bike and push the boulder onto the switch in the bottom-left
392
- Bike toward where you fell down, and follow the ladders to the exit 
393
394
INDIGO PLATEAU
395
- Deposit Squirtle and Paras into the PC
396
- Buy 5 Full Restores (can skip if you have 2) 
397
398
ELITE FOUR
399
- Lorelei: Switch to your flier, let it die, then X Acc, Drill x5 (Dewgong will always use Rest turn 2)
400
- Elixer and save before fighting Bruno
401
	> If below 20 HP, use a Full Restore, and save before Agatha instead
402
- Bruno: X Acc, Drill x5 
403
- Use a Full Restore if you didn't before Bruno
404
- Agatha: X Special, EQ, Blizzard, EQ x3
405
	> If you get put to sleep, use the Poke Flute immediately
406
	> If you miss Blizzard, switch to TB
407
	> If you get Hazed, use an X Speed on Haunter
408
	> The second Gengar outspeeds you and has Night Shade (60 damage)
409
- Stop at least two steps before Lance, and do the following:
410
	> Heal to 129+ HP
411
	> Use the Ether on Horn Drill
412
	> Save
413
- Lance: X Special, TB, Blizzard, X Speed, Blizzard, TB, Blizzard
414
	> If you run out of Blizzards, TB the Dragonite
415
- Heal to 55+ HP
416
- Champion: X Speed, X Acc, Drill x6. If Pidgeot charges Sky Attack on turn 1, use a Full Restore