documentclass{beamer}
usepackage{xcolor}
definecolor{cream}{rgb}{0.9500,0.9451,0.85}
definecolor{sandybrown}{rgb}{ 0.9569 ,  0.6431 ,  0.3765}
newenvironment{myFrame}[2][white]{%
    setbeamercolor{background canvas}{bg=#1}
    begin{frame}{#2}
     }{end{frame}}
%ifxbeamer@currentmodepresentation
ifxbeamer@currentmodehandout
    defslideColor{cream}
else
    defslideColor{sandybrown}
fi
begin{document}
begin{myFrame}[slideColor]{TEST}
end{myFrame}
end{document}