<Directory /var/www/html/mydomain.com/public_html>
    Require all granted
</Directory>

<VirtualHost 127.0.0.1:80 *:80>
    ServerName mydomain.com
    ServerAlias www.mydomain.com
    ServerAdmin webmaster@localhost
    DocumentRoot /var/www/html/mydomain.com/public_html

    WSGIDaemonProcess test user=www-data group=group-wp threads=5
    WSGIScriptAlias /newsletter /var/www/newsletter.wsgi

    <Directory /var/www/html/mydomain.com/public_html/newsletter>
        WSGIProcessGroup test
        WSGIApplicationGroup %{GLOBAL}
        Require all granted
    </Directory>

    ErrorLog /var/www/html/mydomain.com/logs/error.log
    CustomLog /var/www/html/mydomain.com/logs/access.log combined

    RewriteEngine on
    RewriteCond %{SERVER_NAME} =www.mydomain.com [OR]
    RewriteCond %{SERVER_NAME} =mydomain.com
    RewriteRule ^ https://%{SERVER_NAME}%{REQUEST_URI} [END,NE,R=permanent]
</VirtualHost>

import sqlite3
from flask import Flask, g, jsonify, abort, request

app = Flask(__name__)

@app.route('/', methods=['GET'])
def index():
    return "testing"

@app.route('/api/list', methods=['GET'])
def list_all():
    return "also testing"

if __name__ == '__main__':
    app.run()

import sys

sys.path.insert(0, '/var/www/newsletter')

from test import app as application