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import tkinter

def destroy():
    destroy_object = [e1, e2, e3, e4, button, label1, label2, label3, label4, canvas]
    for object_name in destroy_object:
        object_name.destroy()

def draw():
    global canvas
    master.geometry("450x450")
    x1 = int(e1.get())
    y1 = int(e3.get())
    x2 = int(e2.get())
    y2 = int(e4.get())
    destroy()
    canvas = tkinter.Canvas(master, bg="cyan")
    canvas.grid(row=0, column=1)
    canvas.create_oval(x1, y1, x2, y2, fill="red")




master = tkinter.Tk()
label = tkinter.Label(master)
entry = tkinter.Entry(master)
master.geometry("150x150")
canvas = tkinter.Canvas(master, bg="cyan")

def handle_keypress(event):
    if event.keysym == "Space":
        destroy()
        prepare()

canvas.bind("<KeyPress>", handle_keypress)

def prepare():
    global e1, e2, e3, e4, button, label1, label2, label3, label4
    label1 = tkinter.Label(text="X1")
    label1.grid(row=0, column=0)
    e1 = tkinter.Entry(master, width=5)
    e1.grid(row=0, column=1)
    label2 = tkinter.Label(text="X2")
    label2.grid(row=1, column=0)
    e2 = tkinter.Entry(master, width=5)
    e2.grid(row=1, column=1)

    label3 = tkinter.Label(text="Y1")
    label3.grid(row=0, column=2)
    e3 = tkinter.Entry(master, width=5)
    e3.grid(row=0, column=3)

    label4 = tkinter.Label(text="Y2")
    label4.grid(row=1, column=2)
    e4 = tkinter.Entry(master, width=5)
    e4.grid(row=1, column=3)

    button = tkinter.Button(master, text="Создать Овал", command=draw)
    button.grid(row=3, column=0, columnspan=4)
prepare()

master.mainloop()