Guid g = New Guid("Mehar");

string input = "asdfasdf";
using (MD5 md5 = MD5.Create())
{
    byte[] hash = md5.ComputeHash(Encoding.Default.GetBytes(input));
    Guid result = new Guid(hash);
}

/// <summary>
/// Generates Guid based on String. Key assumption for this algorithm is that name is unique (across where it it's being used)
/// and if name byte length is less than 16 - it will be fetched directly into guid, if over 16 bytes - then we compute sha-1
/// hash from string and then pass it to guid.
/// </summary>
/// <param name="name">Unique name which is unique across where this guid will be used.</param>
/// <returns>For example "{706C7567-696E-7300-0000-000000000000}" for "plugins"</returns>
static public String GenerateGuid(String name)
{
    byte[] buf = Encoding.UTF8.GetBytes(name);
    byte[] guid = new byte[16];
    if (buf.Length < 16)
    {
        Array.Copy(buf, guid, buf.Length);
    }
    else
    {
        using (SHA1 sha1 = SHA1.Create())
        {
            byte[] hash = sha1.ComputeHash(buf);
            // Hash is 20 bytes, but we need 16. We loose some of "uniqueness", but I doubt it will be fatal
            Array.Copy(hash, guid, 16);
        }
    }

    // Don't use Guid constructor, it tends to swap bytes. We want to preserve original string as hex dump.
    String guidS = "{" + String.Format("{0:X2}{1:X2}{2:X2}{3:X2}-{4:X2}{5:X2}-{6:X2}{7:X2}-{8:X2}{9:X2}-{10:X2}{11:X2}{12:X2}{13:X2}{14:X2}{15:X2}",
        guid[0], guid[1], guid[2], guid[3], guid[4], guid[5], guid[6], guid[7], guid[8], guid[9], guid[10], guid[11], guid[12], guid[13], guid[14], guid[15]) + "}";

    return guidS;
}