import os
import numpy as np
import pandas as pd
import pickle
import matplotlib.pyplot as plt
import keras
import keras.backend as K
from sklearn.utils import class_weight
from sklearn import dummy, metrics, model_selection, datasets, preprocessing
from sklearn.manifold import TSNE
from sklearn.metrics import accuracy_score
from imblearn.over_sampling import SMOTE
from keras.models import Model
from keras.constraints import non_neg
from sklearn.metrics import roc_curve, auc
from hyperopt import Trials, fmin, hp, tpe,STATUS_OK, STATUS_FAIL
from sklearn.neighbors import DistanceMetric, BallTree