/*
 * Implements hook_ENTITY_TYPE_create()
 */
function MYMODULE_node_create(DrupalnodeNodeInterface $node) {

  if($node->bundle() == 'article') { //check for a content type, ex: article
    $user = DrupaluserEntityUser::load($uid); // load the user
    $user->set('field_name', $some_value); // set a value for a particular field
    $user->save();
  }

}