<?php
set_time_limit(0);
include 'Mail.php';

$host = "localhost";
$username = "username";
$password = "password";
$from = "";
$replyto = "";

$emails = file('emails');
foreach($emails as $to) {
    $headers = array (
                      'From' => $from,
                      'To' => $to,
                      'Reply-To' => $replyto,
                      'Subject' => $subject
                      );
     $smtp = Mail::factory('smtp', array (
                                          'host' => $host,
                                          'auth' => true,
                                          'username' => $username,
                                          'password' => $password)
                                          );

    $mail = $smtp->send($to, $headers, $body);
}

?>