public class Foo
{
 private readonly int bar;

 public Foo(int num)
 {
  bar = num;
 }

 public int GetBar()
 {
  return bar;
 }
}

Foo foo = new Foo(123);
Console.WriteLine(foo.GetBar()); // display 123
// reflection code here...
Console.WriteLine(foo.GetBar()); // display 456

typeof(Foo)
   .GetField("bar",BindingFlags.Instance|BindingFlags.NonPublic)
   .SetValue(foo,567);

using System;
using System.Reflection;

public class Test
{
    private readonly string foo = "Foo";

    public static void Main()
    {
        Test test = new Test();
        FieldInfo field = typeof(Test).GetField
            ("foo", BindingFlags.Instance | BindingFlags.NonPublic);
        field.SetValue(test, "Hello");
        Console.WriteLine(test.foo);
    }
}

SoundDef mySound = Reflection_Modified_Readonly_SoundDef_Field;
if( !(mySound is SoundDef) )
    Log("Welcome to impossible-land!"); //This would run

using System;

namespace TestReadOnly
{
    class Program
    {
        private readonly int i;

        public Program()
        {
            i = 66;
        }

        private unsafe void ForceSet()
        {
            fixed (int* ptr = &i) *ptr = 123;
        }

        static void Main(string[] args)
        {
            var program = new Program();
            Console.WriteLine("Contructed Value: " + program.i);
            program.ForceSet();
            Console.WriteLine("Forced Value: " + program.i);
        }
    }
}