import tkinter as tk

root = tk.Tk()

x = int(root.winfo_screenwidth() //2)
y = int(root.winfo_screenheight() //2)
a = int((root.winfo_screenwidth() - x) // 2)
b = int((root.winfo_screenheight() - y)// 2)
root.wm_geometry("{0}x{1}+{2}+{3}".format(x,y,a,b))
root.overrideredirect(1)

def keydown(e):
    global a
    global b

    if e.char == 'w' or e.char == 'ц':
        b -= 50
    elif e.char == 's' or e.char == 'ы':
        b += 50
    elif e.char == 'd' or e.char == 'в':
        a += 50
    elif e.char == 'a' or e.char == 'ф':
        a -= 50
    root.wm_geometry("{0}x{1}+{2}+{3}".format(x,y,a,b))


close = tk.Button(root, text="Close Window", command=lambda: root.destroy())
close.pack(fill=tk.BOTH)

root.bind('<KeyPress>', keydown)
root.mainloop()