import bpy

get the selected object
selected_object = bpy.context.object

add shapekeys
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)
bpy.ops.object.shape_key_add(from_mix=False)

get its shapekeys
shape_keys = selected_object.data.shape_keys.key_blocks

loop through shapekeys and replace the names
for index, key in enumerate(shape_keys):
    if key.name != "Basis":
        key.name = "Key 0" + str(index)

loop through shape keys and replace the names
for key in shape_keys:
    key.name = key.name.replace("Key 01", "Open_Jaw")
    key.name = key.name.replace("Key 02", "Lips_Corner_In.L")
    key.name = key.name.replace("Key 03", "Lips_Corner_Up.L")
    key.name = key.name.replace("Key 04", "Lips_Corner_Out.L")
    key.name = key.name.replace("Key 05", "Lips_Corner_Dw.L")
    key.name = key.name.replace("Key 06", "Lips_Roll_Top")
    key.name = key.name.replace("Key 07", "Lips_Roll_Bot")
    key.name = key.name.replace("Key 08", "Lips_Corner_In.R")
    key.name = key.name.replace("Key 09", "Lips_Corner_Up.R")
    key.name = key.name.replace("Key 010", "Lips_Corner_Out.R")
    key.name = key.name.replace("Key 011", "Lips_Corner_Dw.R")