drv = '{SQL server}'
svr = 'sql.my-domain.local'
usr = 'my-domain.localtestuser'
pwd = 'password'
db = 'testdb'
pyodbc.connect(driver=drv, server=svr, user=usr, password=pwd, database=db)

pyodbc.Error: ('28000', "[28000] [Microsoft][ODBC SQL Server Driver][SQLServer]
Login failed for user 'svx-iroot.local\sqlexecutive'.
Reason: Not associated with a trusted SQL Server connection. (18452) (SQLDriverConnect)")

tsql -S sql.my-domain.local -U my-domain.localtestuser -P password