> dim(exprs_mat)
[1] 112830   735
> exprs_mat[1:4, 1:3]
        Tarca_001_P1A01 Tarca_003_P1A03 Tarca_004_P1A04
1_at           6.062215        6.125023        5.875502
10_at          3.796484        3.805305        3.450245
100_at         5.849338        6.191562        6.550525
1000_at        3.567779        3.452524        3.316134

> dim(ano)
[1] 735   6
> head(ano)
                       SampleID   GA Batch     Set Train Platform
Tarca_001_P1A01 Tarca_001_P1A01 11.0     1 PRB_HTA     1    HTA20
Tarca_013_P1B01 Tarca_013_P1B01 15.3     1 PRB_HTA     1    HTA20
Tarca_025_P1C01 Tarca_025_P1C01 21.7     1 PRB_HTA     1    HTA20
Tarca_037_P1D01 Tarca_037_P1D01 26.7     1 PRB_HTA     1    HTA20
Tarca_049_P1E01 Tarca_049_P1E01 31.3     1 PRB_HTA     1    HTA20
Tarca_061_P1F01 Tarca_061_P1F01 32.1     1 PRB_HTA     1    HTA20

library(limma)
fit <- limma::lmFit(exprs_mat, design = model.matrix( ~ 0 + t(ano$GA))
fit <- eBayes(fit)
topTable(fit, coef=2)