> EMR
    > carpeta1
        > some.pdf
        > some.xml

import hashlib
def SHA256_Checksum(ruta):
    h = hashlib.sha256()
    with open(ruta, 'rb', buffering=0) as f:
        for b in iter(lambda : f.read(128*1024), b''):
            h.update(b)
    return h.hexdigest()