documentclass{standalone}
usepackage{pgfplots}
usepgfplotslibrary{dateplot}
pgfplotsset{compat=newest}
begin{document}
begin{tikzpicture}

begin{axis}[
  date coordinates in=x,
  xticklabel style={rotate=90,anchor=near xticklabel},
  xticklabel=year-month-day
]
addplot table [red] {%
  2016-10-10 50
  2016-10-11 56
};
end{axis}

end{tikzpicture}
end{document}

documentclass{standalone}
usepackage{pgfplots}
usepgfplotslibrary{dateplot}
pgfplotsset{compat=newest}
begin{document}
begin{tikzpicture}

begin{axis}[
  date coordinates in=x,
  xticklabel style={rotate=90,anchor=near xticklabel},
  xticklabel=year-month-day
]
addplot table [red] {%
  2016-10-10 13:10 50
  2016-10-11 12:55 56
};
end{axis}

end{tikzpicture}
end{document}

! Package PGF Math Error: Could not parse input '12:55' as a floating
point number, sorry. The unreadable part was near ':55'..