28 step stress test

START of Test:
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Step 1. Start a new game using Alternate Start mod (or equivalent).
Step 2. Choose the "I'm camping in the woods" option (or equivalent.) You want to start as close to the guardian stones as you can, but it doesn't really matter.
Step 3. Configure your mods via the MCM menu. Specifically, here, you want to activate all your script-heavy mods, like Frostfall, needs mods, etc, so they're running while you test.
Step 4. At the campsite configure the SoT mod and wait 4 minutes (I usually AFK/alt tab with the game running).
Step 5. Save and exit the game to the desktop. Additionally, using player.forceav speedmult 250, player.additem f 10000, TGM, will make it so you can complete all the steps quickly and easily. I use a bat file that adds a daedric sword, levels all my skills, and sets my HP and damage to max for testing.

Step 6. Load the game and walk/run from the camp site to Riverwood.  Walk/run in more or less a straight line. Make sure to stop and activate one of the guardian stones - this is a good test for interaction mods. Fight any bandits/wolves if you want to.

Step 7. Talk to Alvor in Riverwood and start the main quest.
Step 8. Walk/run from Riverwood to Whiterun Stables.
Step 9. At Whiterun stables, hire the carriage to Solitude.
Step 10. Go slightly to Katla's farm until it is discovered.
Step 11. Wait 11 hours until around 8am in game.
Step 12. Walk/run to Solitude main doors and enter Solitude.
Step 13. Walk/run to the Blue palace and (after the dialogue) talk to Falk Firebeard until the Wolfskull Cave Quest starts.

Step 14. Exit the blue palace.
Step 15. FAST TRAVEL to Katla's farm.
Step 16. From there walk/run to wolfskull cave following the road.
Step 17. Fight the skeletons outside Wolfskull Cave, and enter the cave.
Step 18. Make sure to pick up the Two Handed Axe on the ground at the
start of the cave. (This is a SoT test, but it's still useful here)

Step 19. Make your way through the cave (you can fight the monsters
but it is not necessary. I use KillAll.)

Step 20. At the top of the tower find the Potema-demon summoning
priestess and dispatch her with your axe. I use TCL and Killall to skip to the top of the tower.

Step 21. Pull the lever to put the bridge down and cross over the bridge.

Step 22. OPEN the chest on the other side of the bridge. (Usually it
will crash here if you have too many mods that add levelled lists to
the game) This is an extremely important step.

Step 23. Otherwise, continue until you exit Wolfskull cave.

Step 24. This is where the test really begins... do NOT fast travel!
Walk/run back to Solitude, following the road (i.e. the way you came)

Step 25. As you approach Solitude there is an archway, then after that
there are the main Solitude doors. IF your game is unstable it will
usually crash to desktop (CTD) at the archway, or just after you enter the
Solitude main entrance.

Step 26. IF you make it into Solitude, continue on to Falk Firebeard at the
Blue Palace and complete the quest.

Step 27. Exit the Blue palace and fast travel anywhere on the game map.

Step 28. TCL, player.forceav speedmult 1000, and fly around all the areas on the map for as long as you can. The longer the better. Try to do whatever you can to make the game crash. If the game is still running, it will be nothing short of hyper-stable. I like to listen to a podcast or do my laundry while I hit automove and let my character move from one side of the map to the other - decreased speed takes longer but makes sure everything loads. Faster speed is quicker and more stressful on the test, but might miss issues.