Generation code

import re
from itertools import product, chain
text = re.sub(r"[^\d\n*.]", ".", open(0).read())
vertical_null = [
    r" [\d*.] [\d*.]   \.     \.     \.   [\d*.] [\d*.] ",
]
vertical_options = [
    r" [\d*.]   \.  (  \d  )  \.     \.   [\d*.] [\d*.] ",
    r" [\d*.] [\d*.]   \.  (  \d  )  \.   [\d*.] [\d*.] ",
    r" [\d*.] [\d*.]   \.     \.  (  \d  )  \.   [\d*.] ",
    r"   \.  (  \d     \d  )  \.     \.   [\d*.] [\d*.] ",
    r" [\d*.]   \.  (  \d     \d  )  \.   [\d*.] [\d*.] ",
    r" [\d*.] [\d*.]   \.  (  \d     \d  )  \.   [\d*.]",
    r" [\d*.] [\d*.]   \.     \.  (  \d     \d  )  \.   ",
    r"(  \d     \d     \d  )  \.     \.   [\d*.] [\d*.] ",
    r"   \.  (  \d     \d     \d  )  \.   [\d*.] [\d*.] ",
    r" [\d*.]   \.  (  \d     \d     \d  )  \.   [\d*.] ",
    r" [\d*.] [\d*.]   \.  (  \d     \d     \d  )  \.   ",
    r" [\d*.] [\d*.]   \.     \.  (  \d     \d     \d  )",
]
vertical_special = [
    r" [\d*.]   \.  (  \d  )  \.  (  \d  )  \.   [\d*.] ",
    r"   \.  (  \d     \d  )  \.  (  \d  )  \.   [\d*.] ",
    r"(  \d     \d     \d  )  \.  (  \d  )  \.   [\d*.] ",
    r" [\d*.]   \.  (  \d  )  \.  (  \d     \d  )  \.   ",
    r" [\d*.]   \.  (  \d  )  \.  (  \d     \d     \d  )",
    r"   \.  (  \d     \d  )  \.  (  \d     \d  )  \.   ",
    r"(  \d     \d     \d  )  \.  (  \d     \d  )  \.   ",
    r"   \.  (  \d     \d  )  \.  (  \d     \d     \d  )",
    r"(  \d     \d     \d  )  \.  (  \d     \d     \d  )",
]
left_null = [
    r" [\d*.] [\d*.]   \.   ",
]
left_options = [
    r"(  \d     \d     \d  )",
    r"   \.  (  \d     \d  )",
    r"   \.     \.  (  \d  )",
]
right_null = [
    r"   \.   [\d*.] [\d*.] ",
]
right_options = [
    r"(  \d  )  \.     \.   ",
    r"(  \d     \d  )  \.   ",
    r"(  \d     \d     \d  )",
]
option_products = [
    product(vertical_options, left_options, right_null   , vertical_null   ),
    product(vertical_options, left_null   , right_options, vertical_null   ),
    product(vertical_options, left_null   , right_null   , vertical_options),
    product(vertical_null   , left_options, right_null   , vertical_options),
    product(vertical_null   , left_null   , right_options, vertical_options),
    product(vertical_null   , left_options, right_options, vertical_null   ),
    product(vertical_special, left_null   , right_null   , vertical_null   ),
    product(vertical_null   , left_null   , right_null   , vertical_special),
]
pattern = []
for above, left, right, below in chain.from_iterable(option_products):
    above, left, right, below = above.replace(" ", ""), left.replace(" ", ""), right.replace(" ", ""), below.replace(" ", "")
    pattern.append(rf"(?:(?<={above}.{{134}}{left})\*(?={right}.{{134}}{below}))")
pattern = "|".join(pattern)
pattern = rf"(?s)(?:{pattern})"
pattern = re.compile(pattern)
res = re.findall(pattern, text)
print(sum(int(x) * int(y) for x, y in [(*filter(None, x),) for x in res]))