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- "Is Hirschsprung disease a mendelian or a multifactorial disorder?"
- "List signaling molecules (ligands) that interact with the receptor EGFR?"
- "Is the protein Papilin secreted?"
- "Are long non coding RNAs spliced?"
- "Is RANKL secreted from the cells?"
- "Does metformin interfere thyroxine absorption?"
- "Which miRNAs could be used as potential biomarkers for epithelial ovarian cancer?"
- "Which acetylcholinesterase inhibitors are used for treatment of myasthenia gravis?"
- "Has Denosumab (Prolia) been approved by FDA?"
- "List the human genes encoding for the dishevelled proteins?"
- "Name synonym of Acrokeratosis paraneoplastica."
- "Which are the classes of anti-arrhythmic drugs according to Vaughan-Williams classification?"
- "Which are the different isoforms of the mammalian Notch receptor?"
- "Which are the major characteristics of cellular senescence?"
- "Orteronel was developed for treatment of which cancer?"
- "Is the monoclonal antibody Trastuzumab (Herceptin) of potential use in the treatment of prostate cancer?"
- "Which is the protein that is encoded by the gene GLT8D1?"
- "Which are the Yamanaka factors?"
- "What is the aim of the Human Chromosome-centric Proteome Project (C-HPP)?"
- "Where is the protein Pannexin1 located?"
- "Which currently known mitochondrial diseases have been attributed to POLG mutations?"
- "What is the effect of ivabradine in heart failure after myocardial infarction?"
- "What is the mode of inheritance of Wilson's disease?"
- "Are transcription and splicing connected?"
- "What is the mode of inheritance of Facioscapulohumeral muscular dystrophy (FSHD)?"
- "Is Alu hypomethylation associated with breast cancer?"
- "Which proteins participate in the formation of the ryanodine receptor quaternary macromolecular complex?"
- "What kind of chromatography is HILIC?"
- "What is the effect of TRH on myocardial contractility?"
- "Proteomic analyses need prior knowledge of the organism complete genome. Is the complete genome of the bacteria of the genus Arthrobacter available?"
- "What is the structural fold of bromodomain proteins?"
- "List the endoscopic diagnoses that have been reported in children with autism"
- "What are the outcomes of Renal sympathetic denervation?"
- "Which MAP kinase phosphorylates the transcription factor c-jun?"
- "What is the meaning of the acronym \"TAILS\" used in protein N-terminomics?"
- "Do mutations of AKT1 occur in meningiomas?"
- "What are the main indications of lacosamide?"
- "Which fusion protein is involved in the development of Ewing sarcoma?"
- "List Hemolytic Uremic Syndrome Triad."
- "Does physical activity influence gut hormones?"
- "What are the effects of depleting protein km23-1 (DYNLRB1) in a cell?"
- "Treatment of which disease was investigated in the MR CLEAN study?"
- "Which factors activate zygotic gene expression during the maternal-to-zygotic transition in zebrafish?"
- "Is irritable bowel syndrome more common in women with endometriosis?"
- "What is evaluated using the EORTC QLQ \u2013 INFO25 questionnaire?"
- "Does BNP increase after intensive exercise in athletes?"
- "What is the association of estrogen replacement therapy and intracranial meningioma risk?"
- "Are there web based self management strategies for chronic pain ?"
- "Is Weaver syndrome similar to Sotos?"
- "Which enzyme is targeted by Evolocumab?"
- "Are ultraconserved elements often transcribed?"
- "What is the methyl donor of DNA (cytosine-5)-methyltransferases?"
- "Is peripheral neuroepithelioma related to Ewing sarcoma?"
- "Which signaling pathway does sonidegib inhibit?"
- "In which phase of the cell cycle arrest is impaired in Fanconi anemia?"
- "Which DNA sequences are more prone for the formation of R-loops?"
- "Mutation of which gene is implicated in the familial isolated pituitary adenoma?"
- "which mutations of troponin C gene have been found to cause hypertrophic cardiomyopathy?"
- "What is known about the effect of acupuncture in smoking cessation ?"
- "Which post-translational histone modifications are characteristic of constitutive heterochromatin?"
- "GV1001 vaccine targets which enzyme?"
- "Which is the E3 ubiquitin ligase which ubiquitinates IkB leading to its proteasomal degradation?"
- "Is c-met involved in the activation of the Akt pathway?"
- "Is pregnancy an additional risk during during H1N1 infection?"
- "Is there a crystal structure of Greek Goat Encephalitis?"
- "Are long non coding RNAs as conserved in sequence as protein coding genes?"
- "Mutation of which gene is implicated in the Brain-lung-thyroid syndrome?"
- "What is clathrin?"
- "What are the main results of PRKAR1A Knockdown?"
- "Is TENS machine effective in pain?"
- "Is there any algorithm for enhancer identification from chromatin state?"
- "Which enzyme is targeted by the drug Imetelstat?"
- "Which interleukins are inhibited by Dupilumab?"
- "Which human genes are more commonly related to craniosynostosis?"
- "Are transcribed ultraconserved regions involved in cancer?"
- "In which breast cancer patients can palbociclib be used?"
- "Do patients with Pendred syndrome present congenital deafness?"
- "List side effects of SGLT2 inhibitors?"
- "Is CD56 useful in Ewing sarcoma prognosis?"
- "What is the method FASP used for?"
- "What is the role of extracellular signal-related kinases 1 and 2 (ERK1/2) proteins in craniosynostosis?"
- "Are there any urine biomarkers for chronic kidney disease?"
- "What is being measured with an accelerometer in back pain patients"
- "List the releases of JASPAR database"
- "List symptoms of the IFAP syndrome."
- "Which gene is required for the efficient function of clopidogrel?"
- "Is valproic acid effective for glioblastoma treatment?"
- "Which transcription factor is considered as a master regulator of lysosomal genes?"
- "Which antibiotics target peptidoglycan biosynthesis?"
- "Can Levoxyl (levothyroxine sodium) cause insomnia?"
- "Is fatigue prevalent in patients receiving treatment for glioblastoma?"
- "List two common features of Tay syndrome."
- "Which cell types are known to be driving Rheumatoid Arthritis?"
- "What is the association between personality trait of neuroticism and risk for Alzheimer's disease?"
- "What is the mode of action of everolimus?"
- "Have Quantitative Trait Loci affecting splicing (splicing QTLs) been linked to disease?"
- "Which technique is used for detection of EWS/FLI1 fusion transcripts?"
- "Does the CTCF protein co-localize with cohesin?"
- "What is the application of the Bimolecular Fluorescence Complementation (BiFC) assay in Drosophila embryos?"
- "Which pathological condition of the heart is known as hypertrophic cardiomyopathy (HCM)?"
- "What is the genetic basis of Rubinstein-Taybi syndrome?"
- "What is the function of the viral KP4 protein?"
- "What is the function of the AIRE gene at the embryonic stage?"
- "What is the principle of the PAR-CLIP methodology?"
- "Which drugs are utilized to treat amiodarone-induced thyroitoxicosis?"
- "How is spastic diplegia diagnosed?"
- "Which is the genetic defect causing Neurofibromatosis type 1?"
- "Which is the human selenoprotein that contains several Se-Cys residues?"
- "Which package is available for analysing genomic interactions in R/Bioconductor?"
- "How many clinical trials for off-label drugs in neonates are cited in the literature."
- "Are stress granules involved in the pathogenesis of Amyotrophic Lateral Sclerosis?"
- "Does TGF-beta play a role in cardiac regeneration after myocardial infarction?"
- "Is there a genetic component for happiness?"
- "What enzyme is inhibied by Opicapone?"
- "What kind of affinity purification would you use in order to isolate soluble lysosomal proteins?"
- "Which are the genes thought to be regulated by EWS/FLI?"
- "Do archaeal genomes contain one or multiple origins of replication?"
- "Which pathological conditions are caused by mutations in the CYLD gene?"
- "Which is the genetic basis of Spinal Muscular Atrophy (SMA)?"
- "Which are the common symptoms of Cushing's syndrome?"
- "Which is the third subunit of the TSC1-TSC2 complex upstream of mTORC1?"
- "Which kinase is inhibited by the small molecule KN-93?"
- "What is the effect of Chk2 splice variants on wild-type Chk2 kinase activity?"
- "List genes that have been found mutated in CMT1A (Charcot-Marie-Tooth disease type 1 A)."
- "Which viruses are best known to cause myocarditis?"
- "Which genes have been associated with Cerebral Cavernous Malformation?"
- "Is DITPA a thyroid hormone analog utilized in experimental and clinical studies"
- "What is Tarlov Cyst?"
- "What are 'vildagliptin', 'sitagliptin', 'saxagliptin', 'alogliptin', 'linagliptin', and 'dutogliptin'?"
- "Which is the most important prognosis sub-classification in Chronic Lymphocytic Leukemia?"
- "Is MammaPrint cleared by the United States Food and Drug Administration? "
- "Is amantadine effective for treatment of disorders conciousness?"
- "What is needed for MMP proteins to be functional?"
- "What is hyperosmia"
- "What is the number of long non coding RNAs in the human genome"
- "Which is the most known bacterium responsible for botulism (sausage-poisoning)?"
- "What is the association of spermidine with \u03b1-synuclein neurotoxicity?"
- "List symptoms of 4H leukodystrophy."
- "What is the extracellular core \"matrisome\"?"
- "Is GAGA associated with nucleosome-free regions (NFR)?"
- "Which are the plant DNA (cytosine-5) methyltransferase families?"
- "Where is the histone variant CENPA preferentially localized?"
- "In which proteins is the chromodomain present?"
- "What is Genomicus?"
- "Is amiodarone a class I anti-arrhythmic drug?"
- "Which is the prognostic meaning of delayed enhancement documented in patients hypertrophic cardiomyopathy?"
- "What is the COUGER tool?"
- "Are there drugs for Tick-borne Encephalitis?"
- "Is SLC22A3 expressed in the brain?"
- "Has the protein TIEG1 been associated with apoptosis?"
- "Which is the cellular localization of the protein Opa1?"
- "Which are the drugs utilized for the burning mouth syndrome?"
- "Is PTEN involved in follicular thyroid carcinoma?"
- "Which genome browser database for DNA shape annotations is available?"
- "What is known about clinical efficacy of ceftriaxone for treatment of amyotrophic lateral sclerosis?"
- "What is the relationship between TailorX and Oncotype?"
- "Does strenuous physical activity affect thyroid hormone metabolism?"
- "Which is the main function of \"RNA sponges\"?"
- "Is the gene MAOA epigenetically modified by methylation?"
- "Which mutations of phopspholamban have been found in patients with cardiomyopathy?"
- "Which are the supplemental antioxidant in athletes?"
- "Is glycyl-tRNA synthetase gene involved in the development of Charcot-Marie-Tooth disease?"
- "Is there any software for automated analysis of FISH images?"
- "How do histone methyltransferases cause histone modification?"
- "Is there an increased risk for cancer in Dyskeratosis Congenita?"
- "Does MicroRNA-21 (miR-21) contribute to cardiovascular disease?"
- "What is the enzymatic activity of the breast cancer associated gene BRCA1?"
- "List markers for autophagy."
- "Are there any statistical methods for normalizing and identifying differential regions in histone modification ChIP-seq data?"
- "Is CD84 genetically associated with arthritis?"
- "What is the function of Neu5Gc (N-Glycolylneuraminic acid)?"
- "Are there any specific antidotes for rivaroxaban?"
- "Which metabolite activates AtxA?"
- "What is the function of 6SRNA in bacteria?"
- "Is cytisine superior to nicotine replacement therapy for smoking cessation?"
- "Which amino acid residue appears mutated in most of the cases reported with cadasil syndrome?"
- "Which syndromes are associated with mutations in the EZH2 gene?"
- "Which databases exist for experimentally determined topologies of \u03b1-helical transmembrane proteins ?"
- "Which disease is characterized by congenital absence of intrinsic ganglion cells of the gastrointestinal tract?"
- "What is the disease in which patients are sensitive to DNA crosslinking agents, presenting with a high frequency of chromosomal aberrations?"
- "How is oprozomib administered?"
- "What is a Caveolae?"
- "Which are the roles of chromatin compartments in the eukaryotic nucleus?"
- "Is the abnormal dosage of ultraconserved elements disfavored in cancer cells?"
- "Does thyroid hormone regulate calcium transient in the myocardium? "
- "What are the biological roles proposed for proteins containing the SPRY domain?"
- "How could we infer functional associations from gene fusion events?"
- "The protein NONO forms heterodimers. With which proteins?"
- "Which syndrome is associated with mutant DVL1?"
- "Are proteasome inhibitors good candidates for treatment of leukemia and solid tumors?"
- "Is there any link between CTF4 and CTF18 during sister chromatid cohesion?"
- "What is the Genomic Regions Enrichment of Annotations Tool (GREAT)?"
- "What is the target of the drug Olaparib?"
- "Are thyroid hormone receptor alpha1 mutations implicated in thyroid hormone resistance syndrome?"
- "What is the role of RhoA in bladder cancer?"
- "What is ATAC-seq?"
- "List human proteins that are subject to a dimer-to-tetramer transition."
- "Inhibition of which transporter is the mechanism of action of drug Canagliflozin?"
- "What is the prognostic role of thyroid hormone in patients with heart failure?"
- "which mutations of phospholamban gene have been found to cause hypertrophic cardiomyopathy?"
- "Which gene strand is targeted by transcription-coupled repair (TCR)?"
- "Abnormalities in which chromosomes were linked to the Moyamoya disease?"
- "Which is the branch site consensus sequence in U12-dependent introns?"
- "For what is Protein A from Staphylococcus aureus used in biochemistry?"
- "What is the suggested therapy for Mycobacterium avium infection?"
- "What is the treatment of acute pericarditis?"
- "What is the genetic basis of tuberous sclerosis?"
- "What is the molecular function of the Chd1 protein?"
- "Which drugs are included in the FEC-75 regimen?"
- "Between which probes does the recurrent translocation breakpoint on chromosome 22 of neuroepithelioma lie?"
- "Does administration of triiodothyronine improve outcome following coronary artery bypass grafting?"
- "Which are the most widely used computational methods for the identification of CRMs (cis-regulatory modules)?"
- "Which enzyme does MLN4924 inhibit?"
- "Which protein has been found to interact with phospholamban (PLN) and is also an anti-apoptotic protein?"
- "Is long QT syndrome a cause for sudden cardiac death in athletes?"
- "What is the clinical value of MammaPrint?"
- "Is protein M3/6 a dual specificity phosphatase?"
- "Are there focused databases from which you can retrieve gene expression data on renal disease?"
- "What systems have been developed for the numbering of antibody residues?"
- "Are there any DNMT3 proteins present in plants?"
- "What is the number of protein coding genes in the human genome?"
- "Has vitamin D has been shown to reduce incidence of falls in older people in clinical trials?"
- "What is the indication for prophylactic use of antibiotics in COPD?"
- "Has depression been shown to be a predictor of frailty?"
- "What is the generic name of Gliolan?"
- "Is there any association between Jarid2 and miR-155 in Th17 cells?"
- "What is enCHIP?"
- "How many genes does the human hoxD cluster contain?"
- "Is it safe to take isotretinoin during pregnancy?"
- "Which protein is the E3-ubiquitin ligase that targets the tumor suppressor p53 for proteasomal degradation?"
- "Can DNA intercalators function as topoisomerase inhibitors?"
- "Which diseases is microRNA 132 (miR-132) implicated in?"
- "Which are the human glutamate transporters?"
- "What are the functions of sorting nexin 27?"
- "Do orphan and gene related CpG islands follow power-law-like distributions?"
- "What is the proportion of non canonical splice sites in the human genome?"
- "List protein gel staining methods visualizing the entire protein set."
- "What clinical use aptamers may have?"
- "What is the causative agent of the \"Panama disease\" affecting bananas?"
- "What is the mechanism of action of Nalmefene?"
- "Synostosis of which cranial structures are characteristic to the Mercedes Benz syndrome?"
- "Can valproic acid act as an activator of AMPK?"
- "Which signaling pathways have been associated with medulloblastoma formation and growth?"
- "What is the role of invadopodia in EMT?"
- "What are cancer driver genes?"
- "What is a mitochondrial nucleoid?"
- "What is the treatment of amiodarone-induced thyrotoxicosis?"
- "How does exercise affect thyroid hormone receptors expression in the heart?"
- "Is the Drosophila Translational Control Element (TCE) involved in spermatogenesis?"
- "What are the symptoms of abacavir hypersensitivity?"
- "What is the effect of ivabradine in heart failure with preserved ejection fraction?"
- "Is low T3 syndrome a prognostic marker in patients with renal insufficiency?"
- "Does burning mouth syndrome preferentially affect post-mepopausal women?"
- "Which biomarker is widely used in the diagnosis of Ewing sarcoma?"
- "Proteomic analyses have revealed proteins associated with the triple-negative breast cancers. List some proposed proteins."
- "Which signalling pathway is involved in Tuberous Sclerosis?"
- "Can life style changes reduce oxidative stress"
- "Which is the relation between sweating and anaerobic threshold?"
- "Name monoclonal antibody against SLAMF7."
- "What is the mode of action of bedaquiline?"
- "Does helicobacter pylori infection increase risk for ischemic stroke?"
- "Which are the major types of the motor speech disorder dysarthria?"
- "Is oxidative stress affected by FOXO expression?"
- "Describe the mechanism of action of the LINX system for treatment of gastroesophageal reflux disease."
- "Which enzyme deficiency can cause GM1 gangliosidoses?"
- "What is the characteristic feature of the Dyke-Davidoff-Masson syndrome."
- "Which gene is involved in the development of Barth syndrome?"
- "What is the treatment of subacute thyroiditis?"
- "What are the effects of BMAL1 deficiency?"
- "Which histone modifications are associated with Polycomb group (PcG) proteins?"
- "Where is the protein CLIC1 localized?"
- "List phosphorylation consensus motifs for Casein Kinase 1 (CK1)?"
- "What medication were compared in the ROCKET AF Trial?"
- "Describe the usefulness of the SPIKE database in human signaling pathways"
- "Is the Dictyostelium discoideum proteome known?"
- "List proteins of lipids droplets"
- "What is the Barr body?"
- "Is single-cell analysis (SCA) possible in proteomics?"
- "Is shotgun lipidomics the direct infusion of a lipid sample into a mass spectrometer?"
- "How many genes are in the gene signature screened by MammaPrint?"
- "Is apixaban effective for treatment of acute venous thromboembolism?"
- "Is the tricarboxylic acid (TCA) cycle affected in inflammation?"
- "What are the indications for treatment with anti-hepcidin?"
- "How many genera comprise the Flaviviridae family?"
- "Are reduced-nicotine cigarettes effective for smoking cessation?"
- "Is the Wnt protein modified by notum?"
- "List functions that are evaluated with the Full Outline of Unresponsiveness score?"
- "For the constructions of which organs has 3D printing been tested?"
- "Is ospemifene effective for treatment of dyspareunia?"
- "Is pregabalin effective for treatment of patients with restless leg syndrome?"
- "What is the biological role of expansins in fungi?"
- "Can zinc finger nucleases be used to combat disease?"
- "What is known about depression in acoustic neuroma patients?"
- "Mutation of which gene is associated with Achondroplasia?"
- "What is the mode of action of Hsp90 inhibitors?"
- "Is RET the major gene involved in Hirschsprung disease?"
- "Which type of lung cancer is the most strongly associated with Lambert-Eaton syndrome?"
- "What distinguishes lantibiotics from antibiotics?"
- "List three major features of the CCFDN syndrome."
- "is intense physical activity associated with longevity ?"
- "Are cyclophilins proteins that bind to prolines?"
- "Can a given genotype exhibit opposite fitness effects (beneficial and detrimental) within the same environment?"
- "Has the protein SETMAR (Metnase) a transposase domain?"
- "Is alternative splicing of apoptotic genes playing a role in the response to DNA or mitochondrial damage?"
- "Which oncogenes are able to induce cellular senescence?"
- "What is HbVar?"
- "Can DMSO as an additive improve proteomic analysis results?"
- "The antibodies MK-3475 and CT-011 have shown promising results in treating malignancies. Which protein are they targeting?"
- "Which are the different proteins/isoforms encoded but the ASPH (aspartate beta-hydroxylase) gene in humans?"
- "List processes which are under the control of the YAP protein."
- "What family do mDia proteins belong in?"
- "Is nucleosome eviction ATP-dependent?"
- "Is TREM2 associated with Alzheimer's disease in humans?"
- "Which is the most common measure of differences between dinucleotide relative abundance \"genomic signatures\""
- "Name a method for enrichment of arginine-methylated peptides."
- "Why do we use \"N-terminal proteomics\"?"
- "List omics technologies comprised in system biology."
- "Rindopepimut is an analog of which growth factor?"
- "Which gene mutations are responsible for isolated Non-compaction cardiomyopathy?"
- "From which tissue was the NCI-H520 cell-line derived?"
- "Have mutations in the Polycomb group been found in human diseases?"
- "Describe the mechanism of action of drisapersen"
- "Is microRNA(miRNA) 29 involved in post-ischemic cardiac remodeling?"
- "What is the incidence of Edwards syndrom in the european population?"
- "Is exonuclease Xrn1 a component of the P-bodies?"
- "What is the substrate of the microbial enzyme inulinase?"
- "What is the treatment of acute myocarditis?"
- "List causative genes for autosomal recessive forms of monogenic Parkinson's disease"
- "How does ranolazine affect calcium handling in the heart"
- "Which is the primary distinction between the Reverse Warburg effect and the conventional Warburg effect?"
- "What is the role of per genes in circadian rhythm control?"
- "Can sorafenib activate AMPK?"
- "What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?"
- "When was empagliflozin FDA approved?"
- "Is Vortioxetine effective for treatment of depression?"
- "Which R/bioconductor package is used for integrative genomics visualizations?"
- "List symptoms of congenital toxoplasmosis triad."
- "How many genes are imprinted in the human genome?"
- "Is exome sequencing efficient for the detection of germline mutations?"
- "Which cellular processes are regulated by Nanog?"
- "In which cells are A-type lamins expressed?"
- "What is the definition of autophagy?"
- "Gene silencing can be achieved by RNA interference (RNAi) in eukaryotic organisms. What is the name of the analogous process in prokaryotic organisms?"
- "Between which types of DNA bases are mutational biases introduced due to directional mutation pressure?"
- "Is it feasible to determine the complete proteome of yeast?"
- "Which mutations of alpha-myosin heavy chain gene are implicated in hypertrophic cardiomyopathy?"
- "Which are the cardiac manifestations of Marfan syndrome?"
- "How is connected \"isolated Non-compaction cardiomyopathy\" with dilated cardiomyopathy?"
- "What is the role of AMPK in diabetic cardiomyopathy?"
- "Are circRNAs associated with diseases and traits?"
- "Which is the most common cause of sudden cardiac death in young athletes?"
- "Could the Menzerath-Altmann law be proved mathematically trivial in genomes?"
- "What is the rate of survival after commotio cordis?"
- "What is the oldest human sample analysed by paleontology proteomics?"
- "What are the results of loss of the protein Lon1 in the plant Arabidopsis?"
- "Which gene is involved in Giant Axonal Neuropathy?"
- "Are there studies representing the involvement of Notch mutations in neurodegenerative diseases such as Down syndrome, Pick's and Prion's disease, and cadasil syndrome?"
- "Are there any functional differences between Mfd and its human Cocaine syndrome protein B (CSB) homolog?"
- "What is membrane scission?"
- "How many TAp73 isoforms have been identified in humans?"
- "Is the yeast \u039cac1 transcription factor induced upon copper deficiency?"
- "What is the mechanism of DNA replication termination in vertebrates?"
- "Which are the different members/isoforms of the Ras oncogenes?"
- "Which is the subcellular localization of ERAP2?"
- "Have thyronamines effects on fat tissue?"
- "What are the names of anti-CD52 monoclonal antibody that is used for treatment of multiple sclerosis patients?"
- "Is there a package in R/bioconductor for classification of alternative splicing?"
- "Which brain structures have been investigated as potential targets for deep brain stimulation of patients suffering from major depression?"
- "Is alemtuzumab effective for remission induction in patients diagnosed with T-cell prolymphocytic leukemia?"
- "What is the association between moon cycle and rupture risk of intracranial aneurysms?"
- "Is there an association between TERT promoter mutation and survival of glioblastoma patients?"
- "Is bapineuzumab effective for treatment of patients with Alzheimer's disease?"
- "Which deiodinase polymorphisms are implicated in arterial hypertension?"
- "At which kind of individuals is pharmacological treatment of subclinical hypothyroidism effective in reducing cardiovascular events?"
- "Is intense physical activity associated with longevity?"
- "How homoplasy affects phylogenetic reconstruction?"
- "What is known about the association between the use of selective serotonin reuptake inhibitors during pregnancy and risk for autism in offspring?"
- "Which transcription factors are involved in E-cadherin repression during EMT?"
- "Is desmin an intermediate filament protein involved in Dilated Cardiomyopathy (DCM)?"
- "Is lambrolizumab effective for treatment of patients with melanoma ?"
- "List human diseases involving genomic imprinting."
- "Why are insulators necessary in gene therapy vectors?"
- "Which deficiency is the cause of restless leg syndrome?"
- "What histone modification is recognized by the bromodomain?"
- "What memory problems are reported in the \" Gulf war syndrome\"?"
- "Is cadasil syndrome a hereditary disease?"
- "Which neuroendocrine tumors are associated with specific tumor syndromes?"
- "How many periods of regulatory innovation led to the evolution of vertebrates?"
- "Is nintedanib effective for Idiopathic Pulmonary Fibrosis?"
- "What is the role of SERCA in diabetic cardiomyopathy?"
- "Is pesticide exposure associated with polyneuropathy?"
- "What is the methodological principle of ChIA-PET?"
- "Is there an association between borna virus and brain tumor?"
- "List medication interfering with purine metabolism that are used for treatment of T-cell prolymphocytic leukemia?"
- "Does PU.1 (SPI1) affect NF-kB binding?"
- "Does the majority of the mitochondrial genomes abide to the second parity rule (PR2)?"
- "What is the association between h-index and academic rank in academic neurosurgery?"
- "Is there an association between bruxism and reflux?"
- "What is known about the value of mindfulness interventions in prostate cancer patients?"
- "What is known about prostate cancer screening in the UK ?"
- "Which hormone abnormalities are common in Williams syndrome ?"
- "The secreted frizzled-related protein 3 (sFPR3) is altered in human cancers.\nAre its level found to increase or to decrease?"
- "Albumin depletion is a common first step for proteomic analysis of CSF fluid. What is the advantage and disadvantage of this procedure?"
- "How are lincRNA affecting the regulation of gene expression?"
- "Which is the protein encoded by the human gene GRIK?"
- "Which residue of alpha-synuclein was found to be phosphorylated in Lewy bodies?"
- "Is paroxetine effective for treatment of premenstrual dysphoric disorder?"
- "What is known about thalidomide therapy and survival of glioblastoma patients?"
- "Is endostatin a proangiogenic factor?"
- "List Genes associated with adolescent idiopathic scoliosis"
- "Can botulism poisoning of a pregnant woman harm her fetus?"
- "List the off-label use of SSRIs"
- "Which is the definition of pyknons in DNA?"
- "Does a linker histone exist in the yeast genome?"
- "What is the role of deadenylases in the cell?"
- "What molecule is targeted by brodalumab?"
- "How long, in kb (kilobases), is a \"Long interspersed nuclear element\"?"
- "Which is the gene mutated in type 1 neurofibromatosis?"
- "List receptors of the drug Cilengitide"
- "Can protein coding exons originate from ALU sequences?"
- "How could U1 small nuclear RNA be used in therapeutics?"
- "What is the influence of patent expiry on ACE inhibitor prescribing."
- "Is there evidence that tomato juice lowers cholesterol levels?"
- "Are there transposon-free regions in mammalian genomes?"
- "Are messenger RNA molecules epigenetically methylated?"
- "Which genes are more frequently affected by somatic mutations in Chronic Lymphocytic Leukemia"
- "How effective is the dentritic cells treatment on cancer?"
- "What is the mode of inheritance of nemaline myopathy?"
- "Which syndrome is NHE6 associated with?"
- "What is known about the reimbursement of Viagra"
- "Why is lock mass used in Orbitrap measurements?"
- "Which virus is Cidofovir (Vistide) indicated for?"
- "Have gnotobiotic animal models been used for the study of bowel disease?"
- "List chromosomes that have been linked to Arnold Chiari syndrome in the literature."
- "Which translocation is the hallmark of Ewing sarcoma?"
- "Is invasion and metastasis one of the hallmarks of cancer?"
- "Is it possible to detect survivin protein expression in normal human adult tissues?"
- "List symptoms of Meigs' Syndrome."
- "What is the effect of CRD-BP on the stability of c-myc mRNA?"
- "What is the molecular function of psoralen photobinding on DNA?"
- "Is progesterone effective for treatment of patients with traumatic brain injury based on clinical trial data?"
- "Is there a role for the cylindromatosis tumor suppressor (CYLD) in lung cancer?"
- "Which medical diagnostic tests are used to test kidney function?"
- "Against which protein is the antibody used for immonostaining of Lewy bodies raised?"
- "Which are the main causes of fetal echogenic bowel?"
- "How does trimetazidine affect intracellular kinase signaling in the heart?"
- "Which is the enzymatic activity of the myotubularin family of proteins?"
- "Can we detect DNA strand asymmetries using dinucleotide relative abundance \"genomic signatures\"?"
- "What is the percentage of responders to tetrabenazine treatment for dystonia in children?"
- "Is there any relationship between histone ubiquitylation and splicing?"
- "Which disease can be treated with Delamanid?"
- "What was the aim of the COSS (Carotid Occlusion Surgery Study) clinical trial?"
- "What are the advantages of the top down mass spectrometric analysis of histones?"
- "What is situs inversus?"
- "Can SUMO affect calcium homeostasis?"
- "What is the indication of Daonil (Glibenclamide)?"
- "Which is the most typical peptide sequence responsible for retrieval of endoplasmic reticulum (ER) lumenal proteins from the Golgi apparatus?"
- "What are the clinical trial outcomes of metformin use in polycystic ovary disease?"
- "List the main proteases used for sample digestion in proteomics."
- "Which proteins act as factors that promote transcription-coupled repair in bacteria?"
- "What is the association between Generalized anxiety disorder and mortality risk?"
- "Which molecule is targeted by a monoclonal antibody Mepolizumab?"
- "Which is the major symptom of the Doose syndrome?"
- "Have mutations in the GARS gene been identified to cause Charcot-Marie-Tooth Disease Type 2D (CMT2D)?"
- "Which treatment leads to an increase in neutrophil counts in severe congenital neutropenia?"
- "Which genes are affected in ROMANO-WARD syndrome?"
- "Does melanoma occur in people of African origin ?"
- "What is the effect of resveratrol on mTOR activity?"
- "Are people with blood group O protected against severe Malaria?"
- "Which eye condition is managed by the athens protocol?"
- "What is the role of AMPK kinase in myocardial remodeling after myocardial infarction"
- "What is the mechanism of action of solanezumab?"
- "What are the major clinical Villefranche criteria for classic Ehlers-Danlos syndrome?"
- "What is the treatment of neuropathic pain in children?"
- "Which phenomenon is known as the \"calcium paradox\" in the isolated perfused heart?"
- "Is there a crystal structure of the full-length of the flaviviridae NS5(Methyltransferase - RNA depended RNA Polymerase) ?"
- "How do Hsp70 and Hsp110 affect mRNA stability?"
- "What is Prudent Diet?"
- "What is the role of necroptosis in cancer therapy?"
- "Can venlafaxine block NET and SERT?"
- "Is Rheumatoid Arthritis more common in men or women?"
- "What is FINDbase?"
- "Can vitamin B1 deficiency cause encephalopathy?"
- "Which methyl-CpG-binding protein when mutant becomes the hallmark for Rett syndrome?"
- "Are epigenetic modifications implicated in cardiovascular development and disease?"
- "Which deiodinases are present in skeletal muscle?"
- "Which genes are involved in patient response to warfarin?"
- "Which is the molecular weight of the protein angiogenin?"
- "List sodium glucose co-transporter-2 (SGLT2) inhibitors that have been FDA approved for type 2 diabetes mellitus treatment."
- "What is the gene mutated in the Gaucher disease?"
- "Why does the prodrug amifostine (ethyol) create hypoxia?"
- "What is considered a reliable technique for the definitive cytogenetic diagnosis of Fanconi anemia homozygosity?"
- "Can exosomes be detected in urine?"
- "What is the role of lysine-specific demethylase 1 (LSD1) in hematopoiesis?"
- "For the treatment of which conditions can atypical neuroleptic drugs be used?"
- "Which are the characteristics of Andersen syndrome?"
- "How are induced pluripotent stem cells used in the study and treatment of cardiovascular diseases?"
- "Which disease is included as an additional feature in the Goldberg-Shprintzen syndrome?"
- "Which protein is causing Netherton syndrome?"
- "Mutations in which gene and which protein are associated with Netherton syndrome?"
- "Which disease of the central nervous system is characterized by the presence of Lewy bodies?"
- "Which deiodinase is known to be present in liver?"
- "Which proteins participate in the formation of the Notch transcriptional activation complex?"
- "How is the sequence variability defined in antibodies?"
- "Is the transcriptional regulator BACH1 an activator or a repressor?"
- "Is Kanzaki disease associated with deficiency in alpha-N-acetylgalactosaminidase?"
- "Is Mycobacterium avium less susceptible to antibiotics than Mycobacterium tuberculosis?"
- "What molecule is targeted by suvorexant?"
- "For which type of diabetes can empagliflozin be used?"
- "Which are the main methods for pharmacophore modelling?"
- "Are there conserved noncoding elements identified between genomes of human and teleosts?"
- "How early during pregnancy does non-invasive cffDNA testing allow sex determination of the fetus?"
- "Does cortical spreading depression appear in ischemic penumbra following ischemic stroke?"
- "Is phospholamban a regulatory/inhibitory protein of the Ca ATPase SERCA?"
- "What is TFBSshape?"
- "Is Alpers disease inherited in an autosomal recessive mode?"
- "Is vemurafenib effective for hairy-cell leukemia?"
- "Which are the inhibitors of histone methyltransferases?"
- "What is the main characteristic of Amyotrophic Lateral Sclerosis?"
- "Which genes are regulated by MEF-2 in the heart?"
- "Is there an association between TERT promoter mutation and survival of glioma patients?"
- "Which JAK (Janus kinase) inhibitor is approved for treatment of rheumatoid arthritis?"
- "Which is the mechanism used for synthesis of a highly functional N-truncated dystrophin isoform that attenuates dystrophinopathy?"
- "Which are the newly identified DNA nucleases that can be used to treat thalassemia?"
- "Does ziconotide bind to N-type calcium channels?"
- "How is OCT3 associated with serotonin?"
- "What constitutes an increased risk for individuals with Fanconi anemia?"
- "Is stop codon bypass possible?"
- "Is the protein \u03b21-integrin recycled?"
- "Are BBS mutations involved in syndromic Hirschsprung disease?"
- "Which signaling pathway is activating the dishevelled proteins?"
- "Which is the defective protein causing the lysosomal storage disease Fabry?"
- "Is there any software for automated analysis of immuno-histochemistry images?"
- "Is TALEN being used on stem cells?"
- "Is there an association between bruxism and reflux"
- "what is the role of IGF-1 in cardiac regeneration after myocardial infarction?"
- "What is known about prostate cancer screening in the UK"
- "Can a peptide aptamer be used as protein inhibitor?"
- "List inflammatory caspase proteins?"
- "List invertebrates where ultraconserved elements have been identified."
- "Which gene is most commonly associated with severe congenital and cyclic neutropenia?"
- "what is the role of TGFbeta in cardiac regeneration after myocardial injury?"
- "List two chemotherapeutic agents that are used for treatment of Subependymal Giant Cell Astrocytoma"
- "Are integrins part of the extracellular matrix?"
- "Is Calcium homeostasis important in cardiac physiology and pathophysiology?"
- "List available databases containing information about conserved noncoding elements."
- "What was the purpose of the FANTOM5 project?"
- "Is the gene DUX4 epigenetically regulated in somatic cells?"
- "What is the function of the mammalian gene Irg1?"
- "Have hESC been tested for the treatment of age-related macular degeneration?"
- "What disease in Loxapine prominently used for?"
- "What is the systemic nickel allergy syndrome?"
- "Which antibodies cause Riedel thyroiditis?"
- "What are the effects of ILK ablation?"
- "Does d-tubocurarine (d-TC) induces irreversible inhibition of nicotinic acetylcholine receptor (nAChR) at the neuromuscular junction?"
- "Which receptors are bound by Tasimelteon?"
- "Is zyxin a focal adhesion protein?"
- "What is the role of ELMO1 gene in cell migration?"
- "What is the biological role of K-48 linked protein ubiquitination?"
- "Could DNA (cytosine-5-)-methyltransferases serve as tumour markers?"
- "Which RNA polymerase is used for the replication of viroids?"
- "List Parkin binding partners"
- "What is generic name of drug Adempas?"
- "What is known about Vancomycin dosing in neonates?"
- "Is single guide RNA part of the CRISPR/Cas9 tool or an inhibitor of its function?"
- "What is the target protein of the drug Idelalisib?"
- "Which antiepileptic drug is most strongly associated with spina bifida? "
- "Which bacteria caused plague?"
- "The drug JTV519 is derivative of which group of chemical compounds?"
- "Is the long non- coding RNA malat-1 up or downregulated in cancer?"
- "Oxantel is used for periodontitis treatment. How does it work?"
- "What is apelin?"
- "What is the function of the protein encoded by the gene PABPC4?"
- "What kind of enzyme is encoded by the proto-oncogene ABL1?"
- "What is the mode of inheritance of Romano Ward long QT syndrome?"
- "Which histone modifications have been associated to alternative splicing?"
- "Is phospholamban phosphorylated by Protein kinase A?"
- "Are there telemedicine applications for chronic pain management?"
- "What is a P-body (processing body)?"
- "What is the mechanism of action of decitabine?"
- "Which gene is associated with the Mitchell-Riley syndrome?"
- "Is paramyxovirus involved in human subacute thyroiditis?"
- "What are the mobile applications fields of use for patients ?"
- "Is there any link between the aurora B kinase and the polycomb protein ring1B?"
- "Which are the genes responsible for Dyskeratosis Congenita?"
- "Is CD99 encoded by MIC2 gene?"
- "Name five programs for transcript quantification from RNASeq experiments"
- "What are the main characteristics/symptoms of the \"Brugada\" syndrome"
- "What is the main component of the Lewy bodies?"
- "How does thyroid hormone regulate mitochondrial biogenesis in the myocardium?"
- "What is the link between HOT regions and RNA polymerase recruitment?"
- "List variants of the MC1R gene."
- "Which is the enzyme that degrades decapped mRNAs?"
- "Which phenotypes are associated with heterozygous mutations of the BSCL2 gene?"
- "Which is the target protein of the drug nivolumab?"
- "The CXCR2 receptor is targeted in cancer. Name five antagonists."
- "What is the genomic structure of the FAA (FANCA) gene?"
- "What is Snord116?"
- "What is the functional role of the protein Drp1?"
- "Which is the genetic cause for the development of Fanconi anemia complementation group D1?"
- "Which diseases are caused by mutations in Calsequestrin 2 (CASQ2) gene?"
- "What are the most frequent non-canonical sequence motifs at the donor and acceptor splice sites in vertebrates?"
- "What does isradipine do to L-type channels?"
- "Why does cranberry juice help combat urinary tract infections?"
- "In which diseases have electronic patient diaries been applied ?"
- "Which type of myeloma is ixazomib being evaluated for?"
- "Which are the Atg8 homologs in human?"
- "To which family does the Zika virus belong?"
- "Has the fungus Ashbya gossypii got many nuclei that share cytoplasm?"
- "What is the functionality of the Triplex R/bioconductor package?"
- "Which is the molecular mechanism underlying K-ras alterations in carcinomas?"
- "Is microRNA(miRNA) 30 involved in post-ischemic cardiac remodeling?"
- "List all clinical trials of the polypill."
- "What is transvection?"
- "What is the role of probiotics in gastrointestinal disease?"
- "What is the main symptom of Marfan syndrome patients?"
- "What species is associated with Tetrodotoxin?"
- "How is myotonic dystrophy inherited?"
- "How do HBS1L-MYB intergenic variants regulate fetal hemoglobin?"
- "Which are the mammalian orthologs of Drosophila Yki?"
- "Is statin use associated with improved outcomes after aneurysmal subarachnoid hemorrhage?"
- "What is the typical outer diameter of microtubules (tubulin heterodimers)?"
- "Does molindone affect body weight?"
- "What is the genetic basis of propionic acidemia?"
- "Which protein phosphatase has been found to interact with the heat shock protein, HSP20?"
- "What is the risk in G-CSF treatment for severe congenital neutropenia?"
- "Neurostimulation of which nucleus is used for treatment of dystonia?"
- "Which myosin isozymes are located within the pericuticular necklace of the hair cell?"
- "Which is the treatment strategy followed in spinocerebellar ataxia type 3 for CAG removal?"
- "Where is the angiogenin binding element located?"
- "Which proteins cause cytoplasmic sequestration of NF-kB?"
- "Is the SDHAF2 gene encoding a protein necessary for flavination of SDHA?"
- "What is the mode of inheritance of Marchesani syndrome?"
- "Tumor-treating fields are effective for treatment of which cancers?"
- "Which event results in the acetylation of S6K1?"
- "List angiocrine factors"
- "What is protein carbamylation?"
- "What is the cause of episodic ataxia type 6?"
- "What is the main role of Ctf4 in dna replication?"
- "Could Arimidex (anastrozole) cause hot flashes?"
- "What is the role of Inn1 in cytokinesis?"
- "Which hormone deficiency is implicated in the Costello syndrome ?"
- "List the components of a Replisome Progression Complex (RPC)."
- "What is the definition of minimal absent words?"
- "What is the common feature in congenital central hypoventilation and Mowat-Wilson syndromes?"
- "Which is the most common CFTR mutation in Caucasians?"
- "Which CDK targets control cytokinesis?"
- "Are Alu elements transcribed?"
- "In what type(s) of plant organelles we can detect prolamellar bodies?"
- "What do mepolizumab and reslizumab have in common?"
- "When are itaconic acid levels elevated?"
- "Are chromomethylases present in animal genomes?"
- "Which genes are associated with autosomal dominant Charcot-Marie-Tooth?"
- "Which transcription factors (TFs) participate in the formation of the interferon-beta (IFN-b) enhanceosome?"
- "Is low T3 syndrome related with high BNP in cardiac patients?"
- "List packages for transcription factor binding sites' (TFBS) analysis available in R/Bioconductor"
- "Simpson grading is used to describe resection of which brain tumor?"
- "Where in the cell do we find the protein Cep135?"
- "Is delayed enhancement documented in patients with non-ischemic dilated cardiomyopathy?"
- "Which enzyme is inhibited by Varespladib?"
- "Which protein does empagliflozin inhibit?"
- "What symptoms characterize the Muenke syndrome?"
- "List all reported treatment options for anxiety in autism spectrum disorder."
- "List adenosine A2A receptor antagonists that are used for Parkinson's disease treatment."
- "What is the clinical indication of cardiac T1 mapping magnetic resonance?"
- "Which autophagy pathway is trigered by the KFERQ motif of cytosolic proteins?"
- "Which are the clinical characteristics of TSC?"
- "How does dabigatran therapy affect aPTT in patients with atrial fibrillation?"
- "List fish anti-freeze proteins."
- "Which is the phosphorylated residue in the promoter paused form of RNA polymerase II?"
- "Has overexpression of sirtuins been reported to increase lifespan in budding yeast (Saccharomyces cerevisiae)?"
- "Name the major classes of small non coding RNAs in mammalians?"
- "Describe a diet that reduces the chance of kidney stones."
- "What pharmacological and non-pharmacological interventions can be considered as prophylactic therapies in Cluster Headache patients?"
- "How does phospholamban affect the biological activity of the calcium ATPase SERCA?"
- "List the components of mTOR Complex 2 (mTORC2)."
- "What is known about the Digit Ratio (2D:4D) cancer?"
- "Is TREM2 associated with Alzheimer's disease?"
- "Does the protein mTOR regulate autophagy?"
- "Which are the mains risk factors of metabolic syndrome?"
- "Which multiple kinase inhibitors are used in cancer therapy?"
- "Has proteomics been used in the study of Pick's disease?"
- "Are there any urine biomarkers for bladder cancer diagnosis?"
- "List types of avoided words in bacterial genomes"
- "Which gene(s) should be genotyped in order to prescribe the drug Cetuximab (anti-EGFR)?"
- "Is signal transducer and activator of transcription-3 (STAT3) critical for tumor angiogenesis progression?"
- "Which is the physiological target for LeuRS translational quality control?"
- "Is sumoylation implicated in myogenesis?"
- "What do studies show about the effect of Induced hypothermia in premature babies?"
- "Describe what is the advantage of using a stain free protein gel in a Western Blot experiment?"
- "Which is the target of the drug Denosumab?"
- "Which enzyme is inhibited by a drug fostamatinib?"
- "Is the Miller-Fisher syndrome considered to be a variant of Guillain-Barr\u00e9?"
- "Is Ctf4 involved in sister chromatid cohesion establishment?"
- "What states the second parity rule (PR2)?"
- "Are retroviruses used for gene therapy?"
- "Do lincRNAs play a role in human cancer?"
- "Explain the concept proteostasis."
- "Which gene test can be used for the X-linked myotubular myopathy?"
- "Is there a phylogenetic analysis for HIV?"
- "What is the association between adiponectin and migraine?"
- "Which phenomenon is described as oncogene addiction?"
- "Are there randomised controlled trials on sevoflurane?"
- "In which cells are gasdermins expressed?"
- "Where in a protein can a signal sequence be found?"
- "Can FOXOs modulate longevity?"
- "Which antibody is implicated in the Bickerstaff's brainstem encephalitis?"
- "Which micro-RNAs have been associated in the pathogenesis of Rheumatoid Arthritis?"
- "Is there an association between FGFR3 mutation and plagiocephaly?"
- "Are CD44 variants (CD44v) associated with poor prognosis of metastasis?"
- "Is Bladder training an effective method to treat urge incontinence ?"
- "What is the scope of the OMIA database?"
- "What is the effect of methotrexate in treating uveitis due to juvenile idiopathic arthritis ?"
- "Which are the enzymes involved in the addition of 7-methylguanosine in mRNA?"
- "What is HOCOMOCO?"
- "In which condition was protein S100A7 originally identified?"
- "Do proton pump inhibitors affect thyroxine absorption?"
- "Is PER3 required for CHK2 activation in human cells?"
- "What is the typical alteration of the thyroid profile metabolism early after coronary artery bypass graft surgery?"
- "Which proteins are involved in actin bundling and filopodia formation and function?"
- "What does the SAGA complex acronym stands for?"
- "What is the result of the interaction between TSC1 and PLK1?"
- "What are the characteristics of the \"Universal Proteomics Standard 2\" (UPS2)?"
- "Which polyQ tract protein is linked to Spinocerebellar Ataxia type 2?"
- "Which are the smallest known subviral pathogens of plants?"
- "What causes Katayama Fever?"
- "List clinical trials for prevention of sarcopenia"
- "Which is the database of molecular recognition features in membrane proteins?"
- "Which database is available for the identification of chorion proteins in Lepidopteran proteomes?"
- "Are there any clinical trials of the effect of evening primrose oil on postmenopausal symptoms ?"
- "Is acid alpha-glucosidase the enzyme that causes Pompe disease when mutant?"
- "Which kinase is inhibited by Tripolin A?"
- "Is the optogenetics tool ChR2 light-sensitive?"
- "Is the Prostate- Specific Antigen (PSA) test relevant only for prostate cancer?"
- "List symptoms of Hakim Triad."
- "Which is the cellular target of gefitinib?"
- "What kind of bonds are connecting keratin molecules?"
- "Is autism one of the characteristics of Moebius syndrome?"
- "Is Sarcolipin a regulatory/inhibitory protein of the Calcium ATPase SERCA?"
- "What is the risk of developing acute myelogenous leukemia in Fanconi anemia?"
- "How many different mutations have been associated with Muenke syndrome?"
- "How can the fetal Rhesus be determined with non-invasive testing?"
- "Which genes have been proposed as potential candidates for gene therapy of heart failure?"
- "DX-88 is investigational name of which drug?"
- "What type of arrhythmia is known as bidirectional ventricular tachycardia (BDVT)?"
- "Which genes have been found to be associated with restless leg syndrome"
- "Is the circadian clock involved in ribosome biogenesis?"
- "Can mutations in Calmodulin cause ventricular fibrillation?"
- "Do the Sleeping Beauty or the piggyBac transposons have higher transposition efficiency?"
- "Where does TORC1 sequester during heat stress?"
- "Is rivaroxaban metabolized in kidneys?"
- "What are the side effects of Nalmefene?"
- "Is Hirschsprung disease one of the characteristics of the Mowat-Wilson syndrome?"
- "Which are the most common methods for gene prioritization analysis?"
- "Which is the most common disease attributed to malfunction or absence of primary cilia?"
- "What is the usefulness of ultraconserved elements in phylogeny?"
- "Treprostinil is an analogue for which prostaglandin?"
- "Which are the characteristics of the Meier-Gorlin syndrome?"
- "Which enzyme is deficient in Gaucher's disease?"
- "What is the role of Hsp90 inhibition in cancer therapy?"
- "Which is the most common type of pediatric cerebellar tumor?"
- "Which is the E3 ubiquitin ligase of Hsp90?"
- "Which are the major phycobiliproteins present in cyanobacteria?"
- "Is PLK2 involved in alpha-synuclein phosphorylation in the nervous system?"
- "In which kingdom do microsporidia belong, according to their current classification scheme?"
- "What is the inheritance pattern of Emery-Dreifuss muscular dystrophy? "
- "What is the mechanism of action of anticoagulant medication Dabigatran?"
- "What is the effect of a defective CLN3 gene?"
- "Which genes are regulated by TRalpha2 in the heart?"
- "Is insulin-like growth factor-I (IGF-I) able to affect tendon protein synthesis in classic Ehlers-Danlos syndrome patients?"
- "List available methods for transmembrane protein topology prediction."
- "Does GC content vary markedly within a given isochore?"
- "Is tubulin acetylation involved in cell motility?"
- "List available genetic multicolor cell labeling techiniques in Drosophila"
- "Which growth factors are known to be involved in the induction of EMT?"
- "What is the function of the yeast protein Aft1?"
- "Can PLN mutations lead to dilated cardiomyopathy?"
- "Which is the genetic lesion associated with Huntington\u2019s disease?"
- "Is corpus callosum involved in the Mowat\u2013Wilson syndrome?"
- "Which histone modification discriminates between active and poised enhancers?"
- "What are the properties of super-enhancers?"
- "What is the inheritance pattern of Li\u2013Fraumeni syndrome?"
- "Which pituitary adenoma is common cause of infertility is women?"
- "What is the role of mismatched uracil glycosylase (Mug) in DNA repair?"
- "Which are the cardiac effects of thyronamines?"
- "Matuzumab has been tested for treatment of which cancers?"
- "Which are the synonyms of prostate-specific antigen?"
- "What is the lipid droplet used for in the cell?"
- "What is the function of circular RNA?"
- "Can NXY-059 be used for treatment of acute ischemic stroke patients?"
- "Is flibanserin effetive for Hypoactive Sexual Desire Disorder? "
- "List available biomedical question answering systems."
- "Which dediodinases are present in kidney?"
- "What is the presumed key event in Fanconi anemia pathogenesis?"
- "What is the effect of Allopurinol on asphyxia in neonates?"
- "Is recommended the use of perioperative treatment with thyroid hormone therapy in patients undergoing coronary artery bypass grafting?"
- "When is the protein NFL a biomarker?"
- "Is protein CXCR4 used as a prognostic marker of cancer?"
- "How does thyroid hormone regulate SR-Ca2+ ATPase (SERCA) protein in the heart?"
- "Which trancription factor activates the betalain pathway?"
- "List common symptoms of patients with the DOORS syndrome."
- "Which is the most well-accepted method for Down syndrome non-invasive prenatal diagnosis?"
- "Is the H3K4me3 histone mark related to transcriptional initiation or elongation?"
- "What does polyadenylate-binding protein 4 (PABP4) bind to?"
- "What is the average diameter of intermediate filaments?"
- "Elaborate on the association between Genomic Regulatory Blocks (GRBs) and target genes"
- "Which therapeutic interventions for sarcopenia have been applied"
- "What is the genetic basis of progeria?"
- "What is the function of cryptochrome-1 in mouse?"
- "Describe July Effect."
- "Which intermediate filament (IF) protein can be used as a non-specific marker of the neuronal precursor cells of the subventricular zone?"
- "Which enzyme is involved in the maintenance of DNA (cytosine-5-)-methylation?"
- "Is transcapillary albumin escape altered in diabetic patients?"
- "Which genes does thyroid hormone receptor beta1 regulate in the liver?"
- "Are conserved noncoding elements associated with developmental genes?"
- "In what proportion of children with heart failure has Enalapril been shown to be safe and effective?"
- "Is myasthenia gravis associated with osteoporosis?"
- "Which cell type has the protein Chromogranin A as marker?"
- "Does a selective sweep increase genetic variation?"
- "Which disease phenotypes are associated to PRPS1 mutations?"
- "Is indicated the use of antioxidant supplements in patients at risk for coronary artery disease?"
- "Which are the main functions of the human HuR (ELAVL1) protein in fibroblasts?"
- "Which kinases does baricitinib inhibit?"
- "Is there evidence to suggest that triiodothyronine has neuroprotective properties in traumatic brain injury?"
- "What is the role played by mTOR in hypertrophic response and heart failure?"
- "Is Lysine-specific demethylase 1 (LSD1) a critical regulator of hematopoiesis?"
- "Is K-63 linked protein ubiquitination related to proteasomal degradation?"
- "Could transcription factors act as cell-cell signalling molecules?"
- "Magnetic beads has been used in numerous applications. List some coatings used."
- "is pharmacological treatment of subclinical hypothyroidism effective in reducing cardiovascular events?"
- "Could Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)\ncause sudden cardiac death?"
- "What is the mechanism of action of DNA topoisomerase II inhibitors?"
- "Are histone deacetylase (HDAC) inhibitors good candidates to control metastasis of solid tumors?"
- "Is muscle lim protein (MLP) involved in cardiomyopathies?"
- "Which gene harbors the mutation T790M?"
- "what is the role of FGF-2 in cardiac regeneration after myocardial infarction?"
- "Have 5q35 microdeletions been implicated in Sotos syndrome development?"
- "Tumors of which three organs are classically associated with the multiple endocrine neoplasia type 1 syndrome?"
- "Which is the protein implicated in Spinocerebellar ataxia type 3?"
- "What is Tn-seq?"
- "Is metabolic syndrome related with cardiovascular disease?"
- "Is there any functional association during viral replication between flaviviridae viral RNA depended RNA polymerase and viral helicase?"
- "Are defects in recombination repair involved in carcinogenesis?"
- "Which is the prevalence of cystic fibrosis in the human population?"
- "Are seizures among the neurological symptoms of incontinentia pigmenti?"
- "Which are the different homologs or family members of the hedgehog proteins in mammals?"
- "What does mTOR stands for?"
- "Which is the most common genetic lesion among patients with Joubert Syndrome and a cerebello-oculo-renal phenotype?"
- "Which scales are recommended by the American Heart Association for depression screening in cardiovascular patients? "
- "Is there a genome-wide technique for the detection of R-loop formation?"
- "How is CBX1/M31 related to position-effect variegation?"
- "Can bioprinting use human cells?"
- "Is transcription-associated mutagenesis (TAM) related to gene expression levels?"
- "Is there a pharmacogenetic test for trastuzumab?"
- "Which calcium channels does ethosuximide target?"
- "What is the sedimentation coefficient of the mammalian mitoribosome?"
- "Describe the mechanism of action of aliskiren. "
- "Which proteins act as histone-like molecules in prokaryotes?"
- "Which receptor is targeted by telcagepant?"
- "What is the role of photodynamic therapy for meningioma treatment?"
- "Do carmustine wafers improve survival of glioblastoma patients?"
- "Is Dicer part of the RISC loading complex?"
- "What is the Arnold-Chiari syndrome?"
- "What is the biological role of SERCA2 SUMOylation in cardiac physiology and pathophysiology, such as in heart failure?"
- "Which trinucleotide repeat disorders are affecting the nervous system?"
- "Is hypersensitivity to DNA crosslinking agents a hallmark of Fanconi anemia?"
- "Which are the cellular targets of imatinib mesylate?"
- "Which are the clinical characteristics of Tuberous Sclerosis?"
- "What is known about MER41 repeat sequences?"
- "How functional connectivity of the default mode network changes in patients with disorders of consciousness?"
- "Have C12orf65 mutations been associated with axonal neuropathy and optic atrophy?"
- "List drugs included in the DHAP-R chemotherapy regiment."
- "Are psammoma bodies characteristic to meningiomas?"
- "Which are the most common symptoms in Lambert-Eaton Myasthenic Syndrome?"
- "What is the pyroptotic pathway?"
- "Which types of bacterial microflora are associated with the progression of peri-implantitis?"
- "What are the known families of deadenylases?"
- "Which translocation is harbored in the Askin tumor cells?"
- "What is the function of the AtxA pleiotropic regulator?"
- "Is cystatin C or cystatin 3 used as a biomarker of kidney function?"
- "Which R/bioconductor package utilizes the Hilbert curve in order to visualize genomic data?"
- "Can fetal aneuploidy be detected with non-invasive prenatal testing?"
- "Which packages are used for performing overlap analysis of genomic regions in R/bioconductor?"
- "Is dichlorphenamide effective for periodic paralysis?"
- "What is evaluated with the Hydrocephalus Outcome Questionnaire?"
- "What is known about maternal smoking and brain tumor risk?"
- "Which pathway is activated by ficolin-3?"
- "Is nivolumab used for treatment of Non\u2013Small-Cell Lung Cancer?"
- "Global quantitative phosphoproteomic analyses are emerging. List the preferred technologies for the enrichment for phosphorylated peptides?"
- "Which histone modifications are correlated with transcription elongation?"
- "Does thyroid hormone receptor beta1 affect insulin secretion?"
- "List disorders that have been associated to the polymorphism rs2535629."
- "What is targeted by monoclonal antibody Pembrolizumab?"
- "Does replication timing affect the rate of somatic mutations?"
- "Which metazaon species or taxa are known to lack selenoproteins"
- "What is the mode of inheritance of Facioscapulohumeral muscular\ndystrophy (FSHD)?"
- "Is NOD1 activated in inflammation?"
- "List diseases where protein citrullination plays an important role."
- "What is commotio cordis?"
- "What is the cause of Phthiriasis Palpebrarum?"
- "Does the histidine-rich Ca-binding protein (HRC) interact with triadin?"
- "How are CpG island shores defined?"
- "Does magnesium sulfate improve outcomes of subarachnoid hemorrhage patients?"
- "Which gene is mutated in a subtype of arrhythmogenic right ventricular cardiomyopathy known as Naxos disease?"
- "What is the role of edaravone in traumatic brain injury?"
- "Are there plasma membrane receptors for thyroid hormones?"
- "Which disorder is rated by Palmini classification?"
- "what is the role of erythropoietin in cardiac regeneration after myocardial infarction?"
- "Does Rad9 interact with Aft1 in S.cerevisiae?"
- "Are there any desmins present in plants?"
- "Are viruses involved in the etiology of human subacute thyroiditis?"
- "List core circadian clock genes."
- "Which peripheral neuropathy has been associated with NDRG1 mutations?"
- "Is miR-126 involved in heart failure?"
- "Does resveratrol reduce cardiac remodeling?"
- "Which is the receptor for substrates of Chaperone Mediated Autophagy?"
- "What are the hallmarks of congestive heart failure?"
- "What is the mode of inheritance of short QT syndrome?"
- "List clinical trials that have directly compared microsurgical clipping with endovascular coiling for treatment of ruptured brain aneurysms?"
- "What is the reason for the narcolepsy cases developed after H1N1 influenza vaccination?"
- "Which are the biotracers used for detection of Alzheimer's disease using PET?"
- "What was the purpose of the FANTOM3 project?"
- "In which isochores are Alu elements enriched?"
- "Is oxalate renal excretion increased after bariatric surgery?"
- "Which are the mutational hotspots of the human KRAS oncogene?"
- "Which intraflagellar transport (IFT) motor protein has been linked to human skeletal ciliopathies?"
- "What is the mechanism of action of ocrelizumab for treatment of multiple sclerosis?"
- "What is the link between Nonidet-40 (NP-40) and biotinylation?"
- "Which is the transcript responsible for X-chromosome inactivation?"
- "What are viral vectors used for in optogenetics?"
- "Which domain allowing self-association do exist in TDP-43 and FUS proteins?"
- "Is there a role for transcription factories in genome organization?"
- "Which are the Chompret criteria for Li-Fraumeni syndrome?"
- "When ceritinib used instead of crizotinib?"
- "What type of enzyme is peroxiredoxin 2 (PRDX2)?"
- "Is the length of the poly(A) tail involved in human disease?"
- "Why graphics processing units (GPU) are more suitable for biological tasks than central processing units (CPU)?"
- "Which are the thyroid hormone analogs utilized in human studies?"
- "Are patients with marfan syndrome at increased risk of arrhythmias?"
- "What are the treatments of choice for GIST (gastrointestinal stromal tumor)?"
- "List Kartagener Syndrome Triad."
- "Which disease is associated with the ectopic expression of the protein encoded by the gene DUX4?"
- "Which G protein is essential in the formation and function of lamellipodia?"
- "Which are the main functions of the APOBEC3 family of proteins?"
- "Which histone modifications are associated with constitutive heterochromatin?"
- "What is the main application of SWATH-MS in proteomics?"
- "Do selenoproteins and selenium play a role in prostate cancer prevention?"
- "What can Nothobranchius furzeri be used as a model system for?"
- "What is the function of TALENs?"
- "Has protein citrullination been implicated in rheumatoid arthritis?"
- "Show results of randomised controlled trials for certolizumab pegol."
- "Which is the mass-tag that reveal the ubiquitination of a lysine residue?"
- "Which gene is involved in CADASIL?"
- "What is the role of thyroid hormone receptor alpha1 in insulin secretion?"
- "Do R-loops tend to form at sites of DNA replication?"
- "Which two catechol-O-methyl transferase (COMT) inhibitors can be used for treatment of Parkinson disease?"
- "What are the structures formed when keratin molecules come together?"
- "Which is the prognostic impact of hypothyroidism in patients with acute myocardial infarction?"
- "Which are the main features of CREST and other ALS-linked proteins?"
- "Mutations of which genes have been associated with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)?"
- "What is the relationship between nucleosomes and exons?"
- "List programs suitable for pharmacophore modelling"
- "Is selenium deficiency involved in autoimmune thyroid disease?"
- "List disorders that are caused by mutations in the mitochondrial MTND6 gene."
- "Which are the most common methods for ctDNA (circulating tumour DNA) detection?"
- "Which gene is associated with Muenke syndrome?"
- "Is it safe to use Abatacept during pregnancy?"
- "What is DeepCAGE?"
- "Is STAT3 involved in EIF2AK2-dependent suppression of autophagy?"
- "RTS S AS01 vaccine was developed to prevent which disease?"
- "What are the Topological Domains (TADs)?"
- "What is the vibrational theory of olfaction?"
- "Are CTCF and BORIS involved in genome regulation and cancer?"
- "What is the application of the ASSET algorithm in C.elegans?"
- "Are Sidekick proteins members of the immunoglobulin superfamily?"
- "What are the pyknons?"
- "Which deiodinases are best known to be present in brain?"
- "What are the computational methods for the prediction of beta-barrel transmembrane proteins?"
- "Describe what is the usage of the Theatre software tool for genomic analysis."
- "How are CRM (cis-regulatory modules) defined?"
- "Which is the main regulatory molecule of SERCA2A function in the cardiac muscle?"
- "Which gene is responsible for the development of the Mowat-Wilson syndrome?"
- "How is active neurotoxin of Clostridium botulinum detected?"
- "Which factor interacts with Treslin/TICRR throughout the cell cycle of human cells?"
- "What is oprozomib?"
- "Is there a relationship between junctin and ryanodine receptors?"
- "Which medication should be administered when managing patients with suspected acute opioid overdose?"
- "In which nuclear compartments is heterochromatin located?"
- "Have mutations in the ZEB2 gene been found in any human syndrome?"
- "Which enzymes are involved in global genome nucleotide excision repair (GG-NER) in bacteria?"
- "Is JTV519 (K201) a potential drug for the prevention of arrhythmias?"
- "What is the mechanism of microRNA deregulation in carcinogenesis?"
- "Which type of GTPases is required for amino acid-dependent activation of mTORC1?"
- "In which genomic regions are Alu enriched?"
- "What is the synonym of the lubag disease?"
- "Dracorhodin perchlorate was tested for treatment of which cancers?"
- "What is the role of venous angioplasty in multiple sclerosis?"
- "Are the Fanconi anemia genes a part of the same signalling pathway?"
- "Are there clinical trials using stem cells for the treatment of cardiac disease?"
- "Is DNA methylation an epigenetic modification of chromatin related to gene expression?"
- "Is Growth factor independence 1b (GFI1B) important for hematopoiesis?"
- "Has Revlimid been approved by the US Food and Drug Administration?"
- "Which is the execution time (complexity) of the Smith-Waterman algorithm for the alignment of two sequences"
- "List mutations that are implicated in the Gray Platelet Syndrome."
- "Has single guide RNA been used on human cells?"
- "Is Fibroblast Growth Factor 23 a phosphaturic hormone?"
- "Which type of cell death is known as anoikis?"
- "The small molecule SEA0400 is an inhibitor of which ion antiporter/exchanger?"
- "What is Piebaldism?"
- "Which SLC family is FLVCR1 a member of?"
- "Is amoxicillin used for treatment of malnutrition in children?"
- "Where are the orexigenic peptides synthesized?"
- "What is the mechanism of action of APOBEC3G cytidine deaminase to inhibit HIV-1 replication?"
- "Which inherited disorder is known to be caused by mutations in the NEMO gene?"
- "What is ISMARA?"
- "Is it possible to purify pseudopodia to be used for proteomic analysis?"
- "Where does TDP43 localize in ALS neurons?"
- "List interaction partners for the protein GATA1."
- "Is farnesoid X receptor (FXR) a nuclear receptor?"
- "What histone variants play a role in the DNA damage reponse?"
- "List tele monitoring applications of miniaturised sensors"
- "How are ultraconserved elements called when they form clusters?"
- "What is the basis of the methodology of \"functional class scoring\" (FCS) for the analysis of gene expression data?"
- "What is the Timothy syndrome?"
- "Which disease has been associated to a disruptive ALX1 protein?"
- "How many selenoproteins are encoded in the human genome?"
- "In which process Src, Cortactin and MT1-MMP are playing an essential role?"
- "In which yeast chromosome does the rDNA cluster reside?"
- "Which is the underlying mechanism for exon skipping used to treat Duchenne muscular dystrophy?"
- "What is the advantage of using long nano columns in proteomics?"
- "During which stage of the cell cycle is cohesin deposited on the yeast genome?"
- "Which is the neurodevelopmental disorder associated to mutations in the X- linked gene mecp2?"
- "What is the treatment of Riedel disease (thyroiditis)?"
- "What is the link between Dax1 and Esrrb?"
- "What is dovitinib?"
- "Are DNA helicases involved in progeroid syndromes?"
- "List the diseases for which there are point-of-care breath tests"
- "Is there association of matrix metalloproteinases with behaviour of pituitary adenomas?"
- "What is the evolutionary process described by the \"Muller's ratchet\" model?"
- "Which heat shock protein is found to be upregulated during Hsp90 inhibition?"
- "Which gene is responsible for the development of Sotos syndrome?"
- "What is the name for anorexia in gymnasts?"
- "Is Vitamin D deficiency in pregnant women associated with gestational diabetes?"
- "What are the indications for alteplase?"
- "List scaffold proteins of the ERK signaling pathway."
- "Which are the families of mammalian DNA-(cytosine-5)-methyltransferases?"
- "Which classes of endogenous retroelements are known to date?"
- "What is the association between proBNP serum concentrations and stroke outcomes?"
- "What is the effect that EZH2 has on chromatin?"
- "Does Chromatin Immunoprecipitation (ChIP) show a bias for highly expressed loci?"
- "Is clathrin involved in E-cadherin endocytosis?"
- "What are the generic versions of Viagra"
- "List GATA-1 interacting partners as discovered with the help of the biotinylation tagging approach."
- "Which diseases are associated with Alu element insertion?"
- "Approximately how many recombination hotspots have been found in the yeast genome?"
- "How could iPSCs be used for the treatment of diabetes?"
- "What is the name of the stem loop present in the 3' end of genes encoding for selenoproteins?"
- "Is Propofol used for short-term sedation?"
- "Which proteins are the different members of the NF-kappaB family of transcription factors?"
- "What are the symptoms of Rotor syndrome?"
- "Does splicing occur co-transcriptionally?"
- "List the existing methods for genetic manipulation of cells."
- "Are there clinical trials on stem cells in multiple sclerosis"
- "Which SWI/SNF protein complex subunit has been demonstrated to interact with the FANCA gene product?"
- "Are piRNAs involved in gene silencing?"
- "List representatives of the major fungal hypoxanthine-adenine-guanine transporter families."
- "Which proteins have been identified as RET ligands?"
- "Which substances are dangerous to g6PD deficient individuals?"
- "Which mutations of SCN5A gene are implicated in Brugada syndrome?"
- "What is Sotos syndrome?"
- "What is the CRAPome database?"
- "List all articles on network meta-analysis for smoking cessation"
- "Can RG7112 inhibit MDM2?"
- "Which clotting factor is inhibited by betrixaban?"
- "Which are the most frequent syndromes associated with inherited bone marrow failure?"
- "How is yellow fever virus transmitted?"
- "Are there any specific antidotes for dabigatran?"
- "What is the outcome of TAF10 interacting with the GATA1 transcription factor?"
- "How does TNF affect thyroid hormone receptors?"
- "Which ones are the ESKAPE organisms?"
- "What is the effect of dovitinib on the cell cycle?"
- "What is the involvement of PDGFRB in metastatic medulloblastoma?"
- "What is known as Calcium Induced Calcium Release (CICR) and its role in cardiomyocyte contractility?"
- "What is the action of molindone?"
- "What is the function of the enzymes known as dual specificity phoshpatases (DUSPs)?"
- "How is bladder wall thickness measured?"
- "LY450139 is investigational name of which drug?"
- "Are there any Decision support systems for chronic pain management ?"
- "Which gene has been found to be mutant in Lesch-Nyhan Disease patients?"
- "Which is the methyl donor of histone methyltransferases?"
- "How are human accelerated regions (HAR) defined?"
- "Carbapenemase-producing gram-negative bacteria is a major health concern because their resistance to antibiotics.\nList the most frequent carbapenemases found in Enterobacteriaceae."
- "How are GRBs (Genomic Regulatory Blocks) defined?"
- "What is the gene frequently mutated in Multiple endocrine neoplasia 2 (MEN2) and Hisrchsprung disease?"
- "Which are the clinical characteristics of isolated Non-compaction cardiomyopathy?"
- "What is STARR-seq?"
- "In which genomic positions is the histone variant macroH2A enriched?"
- "Does amiodarone affect thyroid hormone receptors in the myocardium?"
- "From which sequence does the Alu repeat originate from?"
- "Abnormality in which vertebral region is important in the Bertolotti's syndrome?"
- "What does iBAQ stand for in proteomic analysis?"
- "Which is the main target of the anti-arrhythmic activity of flecainide?"
- "Does thyroid hormone affect cardiac remodeling?"
- "What is the effect of ROS on cyclin B1?"
- "Are there any HCV replication inhibitors available?"
- "Provide examples of how molecular transporters contribute to multi-drug resistance in bacteria."
- "What is the minimal genome build?"
- "Is cocaine use associated with increased risk for intracerebral hemorrhage?"
- "Is miR-21 related to carcinogenesis?"
- "Which is the most prevalent form of arrhythmia worldwide?"
- "Are thyroid hormone receptor alpha1 mutations implicated in thyroid hormone resistance syndrome?"
- "Which agents are included in the FLAMSA chemotherapy regimen?"
- "Which are the subunits of the IkB protein kinase (IKK)?"
- "Is PLK2 involved in alpha-synuclein phosphorylation in Parkinson disease?"
- "Which glands are subject to attack by lymphocytes in Sjogren's syndrome?"
- "Describe Malgaigne fracture."
- "Name five popular computer programs used to identify genes in genomic sequences"
- "Which are the major transcription factors regulating glycolysis in mammals?"
- "Mutations in which gene determine response to both erlotinib and gefitinib?"
- "Which protein complexes contain mitofilin?"
- "Define marine metaproteomics"
- "Mutation of which gene and which chromosome cause Neurofibromatosis type I?"
- "Which genes does thyroid hormone receptor alpha1 regulate in the heart?"
- "What is the content of the METLIN database?"
- "Which is the RNA sequence of the canonical polyadenylation signal?"
- "Which computational frameworks are available for predicting enhancers?"
- "Which proteins in the cerebro-spinal fluid can be used for early diagnosis of Alzheimer's disease?"
- "Is there evidence for somatic mosaicism in Tuberous Sclerosis?"
- "What is GRO-seq?"
- "What is the role of the RUNX1-MYEF2 complex?"
- "Does smoking increase risk for glioblastoma?"
- "Which genes are implicated in short QT syndrome?"
- "What is SCENAR therapy used for?"
- "List symptoms of Gradenigo's syndrome."
- "Is Wnt16b secreted in response to chemotherapy?"
- "Do DNA double-strand breaks play a causal role in carcinogenesis?"
- "Do conserved noncoding elements co-occur with matrix-attachment regions?"
- "What is the relationship between thyroid hormone and inflammatory markers in heart failure patients?"
- "Which variables are included in the SPAN-100 score?"
- "Are Drosophila ultraconserved elements candidate ncRNAs?"
- "Which genes does thyroid hormone receptor alpha1 regulate in the liver?"
- "What is the color of the protein Ranasmurfin?"
- "What is the role of Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) in development?"
- "Does surgery for ovarian endometriomas improve fertility?"
- "Are ACTA1 (alpha actin) and NEB (nebulin) genes related to nemaline myopathy?"
- "What are the pregnancy outcomes in rheumatoid arthritis?"
- "What is DNAshape?"
- "How are thyroid hormones involved in the development of diabetic cardiomyopathy?"
- "By which methods can we evaluate the reliability of a phylogenetic tree?"
- "Which histone modification is primarily linked to elongating transcription?"
- "Could RG7112 be used as cancer therapy?"
- "Which interleukin is blocked by Siltuximab?"
- "ROSIER scale is used for which disorder?"
- "How histone deacetylation causes transcriptional gene silencing?"
- "Which is the subcellular localization of the protein angiogenin?"
- "List FDA approved treatments for androgenetic allopecia"
- "Which bone protein is used in archaelogy for dating and species identification?"
- "Does thyroid hormone affect cardiac remodeling ?"
- "What is the effect of SAHA treatment in Huntington's disease?"
- "What is known about the role of mHealth in the prevention of disease?"
- "Which receptors are targeted by suvorexant?"
- "Is armodafinil used for treatment of insomnia?"
- "A common problem in proteomics is the contamination of samples with exogenous proteins (often from other species). These proteins can be found in specific databases. List some contaminants."
- "Which gene has been implicated in Majeed Syndrome?"
- "What is Trypan blue used for?"
- "Selexipag is used for which disease?"
- "How does ranolazine affect kinase signaling activation in the heart?"
- "List features of the DEND syndrome."
- "What is the RESID database?"
- "Pridopidine has been tested for treatment of which disorder?"
- "Are there currently applications of deep learning in genomics?"
- "Are CpG islands located close to housekeeping genes?"
- "Is COL5A2 gene associated to ischemic heart disease?"
- "Which is the target of bortezomib used in cancer therapy?"
- "Have microRNAs been implicated in pharmacogenomics? "
- "Which genes are known to be involved in Diamond-Blackfan anemia?"
- "Is nicotinamide effective for skin cancer prevention?"
- "Which is the chromosomal location of the gene MAOA?"
- "Do Parkinson's disease patients experience stridor?"
- "Which depression rating scales were shown to have acceptable psychometric properties for screening of poststroke depression?"
- "What is the mechanism of action of trichostatin A (TSA) as an antitumoral agent?"
- "Is there an association between serum interleukin-6 concentrations and outcomes of stroke patients?"
- "Could bioprinting be used in regenerative medicine against bone disease?"
- "Idarucizumab is an antidote of which drug?"
- "What are the main clinical characteristics of Pendred syndrome?"
- "What is the Pfam database?"
- "What is a popular mesaure of gene expression in RNA-seq experiments?"
- "Is macroautophagy a selective degradation process?"
- "Inhibition of which enzyme is mechanism of action of alisertib?"
- "List the three most prevalent pathogenic species of Borrelia in Europe."
- "Which thyroid hormone transporter is implicated in thyroid hormone resistance syndrome?"
- "Which are the subunits of the transcription factor NF-kappaB in the canonical pathway activation?"
- "Is there any link between conserved noncoding elements and alternative splicing in vertebrates?"
- "Which protein is affected by dusp8 activation?"
- "Which receptors are targeted by a drug Macitentan?"
- "What is known as the cause of subacute thyroiditis?"
- "Which drugs are utilized to treat eosinophilic esophagitis?"
- "What is the incidence of cystic fibrosis in the caucasian population?"
- "What is the effect of thapsigargin treatment?"
- "What is the Her2 status in Li-Fraumeni syndrome?"
- "Where is X-ray free electron laser used?"
- "Which protein kinases have been found to phosphorylate Phospholamban and affect its biological activity?"
- "Why can't humans synthesize Neu5Gc (N-Glycolylneuraminic acid)?"
- "Which enzyme is inhibited by Orteronel?"
- "What is the disorder in which mutations in U4atac snRNA are detected?"
- "Which is the binding site motif of Sp1?"
- "List autoimmune disorders associated with GAD65 autoantibodies."
- "Elaborate on the TREAT-NMD initiative for DMD patients"
- "Is muscle regeneration possible in mdx mice with the use of induced mesenchymal stem cells?"
- "List the different subtypes of thyroid cancer."
- "What are the characteristics of Christianson syndrome?"
- "Is the SDHAF2 gene encoding a protein necessary for flavination of SDHA?"
- "What is the physiological role of LKB1 involved in Peutz-Jeghers syndrome?"
- "What heterotachy states about molecular evolutionary processes?"
- "What is known about depression in caregivers of brain tumor patients?"
- "What are the effects of homozygosity of EDNRB mutations in addition to Hirschsprung disease?"
- "What is the prognostic role of alterred thyroid profile after cardiosurgery?"
- "List Pentalogy of Fallot."
- "Which is the major function of sororin?"
- "Which gene fusion is the result of the \"philadelphia translocation\" or the \"philadelphia chromosome\" mutation?"
- "Is zolpidem an antibiotic?"
- "Can desvenlafaxine be used at a dose of 50mg/day?"
- "Which syndrome is associated with OATP1B1 and OATP1B3 deficiency?"
- "Which type of lung cancer is afatinib used for?"
- "Can ferric carboxymaltose be used to treat anemia in inflammatory bowel disease patients?"
- "Which disease is treated with Eliglustat?"
- "List algorithms suitable for predicting protein complexes"
- "What are piggyBAC transposons?"
- "Is there any association of the chromosomal region harboring the gene ITIH3 with schizophrenia?"
- "Is APOBEC3B protein predominantly cytoplasmic or nuclear?"
- "Is the regulation of Vsr endonuclease independent of the growth phase of bacteria?"
- "Are there interactomes available for POU5F1 and SOX2?"
- "Which tool is used for promoterome mining using CAGE data?"
- "Is Rheumatoid Arthritis related to myopathy?"
- "what is the role of GATA-4 in regeneration of the heart after myocardial infarction?"
- "What is the life expectancy of professional athletes in respect to the general population?"
- "Is EZH2 associated with prostate cancer?"
- "How does adrenergic signaling affect thyroid hormone receptors?"
- "What are the computational tools for the prediction of beta-barrel transmembrane proteins?"
- "Which kinase is regulating stress granule biogenesis?"
- "What is the association between cell phone use and glioblastoma?"
- "Is there any cross-talk between the Wnt and the Akt pathways?"
- "Has the protein GFP been used in transgenesis for live protein imaging?"
- "Is the Snord116 cluster associated with the Prader-Willi syndrome?"
- "Aleglitazar is agonist of which receptor?"
- "What are the main characteristics of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)?"
- "Is poly (ADP- ribosylation) involved in transcriptional control?"
- "Is nimodipine recommended for prevention of vasospasm in aneurysmal subarachnoid hemorrhage patients?"
- "what is the role of prostaglandins in cardiac regenaration after myocardial infarction?"
- "What is the general function of H3K79 methylation?"
- "Where can we find the protein lacritin?"
- "Where can we find the protein dermcidin?"
- "What is the triple screening test performed during pregnancy measuring?"
- "What are the generic versions of Viagra?"
- "Which protein interacts with the Ragulator-RAG GTPases to control mTOR activity?"
- "Against which organisms has reverse vaccinology been used?"
- "Galassi classification is used for which disorder?"
- "Describe Mozart effect."
- "What is the purpose of the Tokuhashi scoring system?"
- "Which compounds exist that are thyroid hormone analogs?"
- "Is lenvatinib effective for thyroid cancer?"
- "What genes are related to breast cancer?"
- "To the ligand of which receptors does Denosumab (Prolia) bind?"
- "List fluorescent reporter proteins."
- "By which mechanism MutT proteins act against DNA lesions in bacteria?"
- "Was tamoxifen tested for treatment of glioma patients?"
- "Which transcription factors are known as the four (4) \"Yamanaka factors\" that have been used to create induced pluripotent stem cells (iPSCs)?"
- "What is the role of anhedonia in coronary disease patients?"
- "What is the clinical value of naltrexone in Parkinson's disease patients?"
- "What is the efficacy of oxaliplatin monotherapy in the management of colorectal cancer?"
- "Are there any animal models for Niemann-Pick C1 disease?"
- "Which type of genes are modulated by SATB1?"
- "Does HER2 under-expression lead to favorable response to trastuzumab?"
- "Which are the most abundant human lincRNA?"
- "Which is the molecular function of the protein CCDC40?"
- "Is the PTPN22 gene a biomarker for rheumatoid arthritis?"
- "Can administration of the thyrotropin releasing hormone reduce fatigue in cancer patients?"
- "What is the role of chromomethylases in plants?"
- "Is curcumin a phytochemical?"
- "What is Cerebral Cavernous Malformation?"
- "Is Fanconi anemia presented as a genetically and clinically heterogeneous disease entity?"
- "What is the treatment of interferon-induced thyroiditis?"
- "Which protein pathway is regulating SGK1-mediated phosphorylation of FOXO3a to control cell proliferation?"
- "Which drugs have been found effective for the treatment of chordoma?"
- "Which components of the stress granules are known to be related to motor neuron degeneration in Amyotrophic Lateral Sclerosis?"
- "Is there evidence for de novo genesis of enhancers in vertebrates?"
- "Which could be some of the possible causes of hypersomnia?"
- "What is the function of caspases?"
- "Is TNNI3K a cardiac-specific protein?"
- "How does Rif1 regulate DNA replication?"
- "Is factor XI deficient in Hemophilia C?"
- "What is known about food intolerance and gluten ?"
- "Are EDNRB mutations involved in the development of Hirschsprung disease?"
- "What is known about the effectiveness of electronic food diaries ?"
- "Can the apoptosis regulator BAX trigger the release of cytochrome c?"
- "Which biological process in known as Endoplasmic Reticulum-Associated Protein Degradation (ERAD)?"
- "List BRAF inhibitors that have been tested in clinical trials for treatment of melanoma patients"
- "which are the risk factors for sudden cardiac death in patients with hypertrophic cardiomyopathy?"
- "What is known about the economic cost of urinary incontinence?"
- "Which are the coactivators of the Yes-associated protein (yap)?"
- "How many genes outside of the MHC locus have been genetically associated to Rheumatoid Arthritis through GWAS?"
- "Are optogenetics tools used in the study and treatment of epilepsy?"
- "In which phase of cell cycle does stress-induced transcription-associated mutagenesis (TAM) occur?"
- "Which proteins are related to the loss of cell-cell adhesion during EMT (epithelial-mesenchymal transition)?"
- "Is micro RNA 1 (miR-1) implicated in cardiac arrhythmias?"
- "Are there Conserved Noncoding Elements (CNEs) in invertebrate genomes?"
- "Which tumor suppressor is referred to as \"the guardian of the genome\"?"
- "What is known about diseases associated with mutations in the CHCHD10 gene?"
- "Which drug should be used as an antidote in benzodiazepine overdose?"
- "Does thyroid hormone signaling affect microRNAs expression in the heart?"
- "Give examples of next-generation sequencing applications in mutation screening?"
- "List common features of Shapiro syndrome"
- "List mouse models for autism spectrum disorder (ASD)."
- "What is BioASQ?"
- "Which are the main functions of G3BP1 and G3BP2 proteins?"
- "What is the definitive treatment for low pressure headache?"
- "What is the role of the histidine rich calcium binding protein (HRC) in cardiomyopathy?"
- "What is the incidence of sudden cardiac death among young athletes?"
- "What is the effect of amitriptyline in the mdx mouse model of Duchenne muscular dystrophy?"
- "Which post-translational histone modifications are characteristic of facultative heterochromatin?"
- "Mutations in which genes have been associated with Aicardi-Goutieres syndrome?"
- "List bacteria that may be useful in uranium bioremediation."
- "How much should be the duration of the QT interval in patients with short QT syndrome?"
- "What is known about potential implication of thyroid hormone receptors in arterial hypertension?"
- "What is the mechanism of action of abiraterone?"
- "The protein neprilysin has an positive effect on Alzheimer disease, how can it be delivered to the brain?"
- "Which species of bacteria did the mitochondria originate from?"
- "Which disease is linked to mutations within BRAG1?"
- "Which is the main calcium pump of the sarcoplasmic reticulum?"
- "What is the inheritance pattern of Hunter disease or mucopolysaccharidosis II?"
- "Do ephrins play a role in brain cancer?"
- "What is the effect of the absence of Saccharomyces cerevisiae Rrm3p?"
- "Do all archaea possess multiple origins of DNA replication?"
- "What is the ubiquitin proteome?"
- "Which major signaling pathways are regulated by RIP1?"
- "What is the effect induced by sympathetic nervous system on pupil size?"
- "Is p100 the precursor protein molecule of the NF-kappaB transcription factor subunit p50?"
- "What is the definition and the biological role of epithelial-mesenchymal transition (EMT)"
- "Is there a difference in the rate between gene fusion and gene fission?"
- "What type of cancers and inherited diseases have been associated to mutations in the Notch pathway?"
- "Can cognitive behavioral therapy improve fatigue in cancer patients?"
- "Is protein Fbw7 a SCF type of E3 ubiquitin ligase?"
- "Is there increased incidence of incontinence in athletes?"
- "What is the inheritance pattern of Apert syndrome?"
- "Which is the most widely used model for the study of multiple sclerosis (MS)?"
- "What is the usual HER-2 status in breast cancer associated with Li-Fraumeni syndrome?"
- "What is the treatment of triiodothyronine toxicosis?"
- "Are there enhancer RNAs (eRNAs)?"
- "Which are the known human transmembrane nucleoporins?"
- "Which E3 ubiquitin ligase mediates the ubiquitination and degradation of the interferon receptor type 1 (IFNAR1)?"
- "Are conserved noncoding elements associated with the evolution of animal body plans?"
- "Which genes were found to be methylated in bladder cancer cells?"
- "Are DNA methylation maps applicable to the diagnosis of non-small-cell lung carcinomas?"
- "Which domain of TIA-1 is necessary for stress granule assembly?"
- "Is the protein product of the cylindromatosis gene (CYLD) a deubiquitinating enzyme?"
- "What is the characteristic domain of histone methyltransferases?"
- "What is smFISH?"
- "Which are the bioinformatics tools for gene structure prediction?\n"
- "Which is the major phytoalexin in alfalfa (Medicago sativa L.)?"
- "What is the correlation between SPARC expression and growth inhibition in human cancer?"
- "Which syndrome is associated with mutations in the LYST gene?"
- "Has the presence of delayed enhancement been documented in athletes performing strenuous exercise?"
- "How does dronedarone affect thyroid hormone signaling in the heart?"
- "Name the factors required for selenoprotein synthesis in eukaryotes"
- "What are the functions of the ESCRT machinery?"
- "Which genes/proteins have been found to inhibit cyclin dependent kinase 4 (CDK4)?"
- "What is the role of TRH in hypertension?"
- "Is triadin involved in cardiac function?"
- "Which disorders are associated to mutated Hepcidin (HAMP)?"
- "Which protein is the main inhibitor of protein phosphatase 1 (PP1)?"
- "What is the role of NETs in systemic lupus erythematosus?"
- "Which protein is required for Argonaute 2 recruitment to stress granules and P-bodies?"
- "Is Mammaprint approved by the United States Food and Drug Administration?"
- "What is known as Von Hippel\u2013Lindau disease or syndrome?"
- "Is HER2 active only when it dimerizes?"
- "Which pharmacogenetic test is available for abacavir?"
- "Are microRNA (miR) regulated through DNA methylation of their promoters?"
- "Are nucleosomes positioned at DNA replication origins?"
- "Which are the most under-represented oligonucleotides in higher eukaryote genomes?"
- "Does nimotuzumab improve survival of glioblastoma patients?"
- "List co-morbidities that may occur together with \"Stiff man Syndrome\""
- "Which mechanisms underlie adaptive mutagenesis (stationary-phase mutagenesis) in Bacillus subtilis?"
- "What personality traits can be evaluated with the Ten Item Personality Inventory."
- "Which are the enzymes involved in the control of tubulin acetylation?"
- "Is there a relation between ANP and transcapillary albumin escape?"
- "List all approved indications for Glivec"
- "Which proteins induce inhibition of LINE-1 and Alu retrotransposition?"
- "Can chronological age be predicted by measuring telomere length?"
- "What is a benefit of being g6PD-deficient?"
- "Describe the usefulness of Macrostomum lignano in ion channel and stem cell research"
- "Is there an association between c-reactive protein concentrations and outcomes of subarachnoid hemorrhage patients? "
- "Which drug is benserazide usually co-administered with?"
- "What is the inheritance pattern of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) caused by RYR2 mutations?"
- "What is the INSURE procedure in premature babies."
- "Which are the available biomedical text mining tools for the detection of protein-protein interactions?"
- "How thyrocyte destruction is induced in autoimmune thyroiditis?"
- "Do A-type lamins bind euchromatin or heterochromatin?"
- "Which is the most abundant membrane protein on Earth?"
- "Can RNASeq be used for the analysis of nascent transcripts?"
- "Do RNA:DNA hybrids preferentially form in high or low GC regions?"
- "Which are the most commonly reported pathological states associated with the formation of DNA G-quadruplexes?"
- "Are shadow enhancers associated with development?"
- "Does prudent diet reduce cardiovascular risk?"
- "Is Crohn's disease (CD) linked to the consumption of refrigerated food?"
- "Which drugs are included in TAS-102?"
- "What is the most probable defect underlying triple negative breast cancer?"
- "What causes erucism?"
- "How does Hst5 (histatin 5) affect infections by Candida glabrata?"
- "Which enzyme is deficient in Krabbe disease?"
- "Are there Conserved Noncoding Elements (CNEs) in plant genomes?"
- "Which is the localization of the RIFIN family of proteins?"
- "What are the current treatments for generalised anxiety disorder in teenagers?"
- "Can tetracycline affect tooth formation?"
- "Is there any genetic determinant of hair pigmentation that could be useful in forensic analyses?"
- "What is the suggested clinical management of Fanconi anemia?"
- "Could Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) cause sudden cardiac death?"
- "Does Apolipoprotein E (ApoE) have anti-inflammatory activity?"
- "Which drugs acting via bradykinin system are effective for treatment of ACE-inhibitor-induced angioedema?"
- "Is the ACE inhibitor indicated for lung cancer treatment?"
- "Which forms of cancer is the Tpl2 gene associated with?"
- "What are the indications for hydrochlorothiazide?"
- "Are genes symmetrically distributed between leading and lagging DNA strand in bacteria?"
- "What hand deformities do patients with Apert syndrome present with?"
- "Is c-myc subject to regulation by the circadian clock?"
- "What disease is Velcade (bortezomib) mainly used for?"
- "Which genes are thought to be involved in medulloblastoma development?"
- "What is the prevalence of short QT syndrome?"
- "Which sports have a risk for commotio cordis?"
- "is there an increase in ultrasound comets after intense exercise?"
- "Describe Hot water reflex epilepsy."
- "What are the breath test biomarkers of pulmonary tuberculosis"
- "What types of DNA mutations are induced by 2-hydroxy-dATP (2-OH-dATP)?"
- "Which diseases can be treated with Afamelanotide?"
- "Which is the mechanism used by bacteria to induce tumors in Arabidopsis?"
- "Can cffDNA be used for non-invasive testing?"
- "List features of the Perry syndrome."
- "Which is the main calcium binding protein of the sarcoplasmic reticulum?"
- "Is the UGT1A1*28 polymorphism associated with irinotecan response in Caucasians?"
- "For which diseases members of the 2-aminobenzamide class of histone deacetylase (HDAC) inhibitors show promise as therapeutics?"
- "Do U6-associated proteins Lsm4 and Lsm6 interact with SMN?"
- "List anti-amyloid-beta monoclonal antibodies that have been investigated in clinical trials for treatment of Alzheimer disease."
- "Does MVIIA and MVIIC bind to the same calcium channel?"
- "What is the idea behind the fractal globule that has been proposed as a model of chromatin conformation in the nucleus of a cell?"
- "Which anticancer drugs target human topoisomerase II?"
- "What is SHAPE-Seq?"
- "Which are the known inhibitors of the TPL2/MAP3K8 protein?"
- "What is the mode of inheritance in Fanconi anemia?"
- "Describe the involvement of conserved noncoding sequences in the regulation of Hox genes."
- "Give an overview of visualizing genomes with oligopaint FISH probes."
- "What is Targeted Chromatin Capture (T2C)?"
- "What are the reported adverse effects of topical minoxidil?"
- "Is arimoclomol a co-inducer of the heat shock response?"
- "What memory problems are reported in the \" Gulf war syndrome\""
- "Describe Heyde syndrome."
- "Has silicon been used in treatment of incontinence ?"
- "Which proteins compose the error prevention GO (8-oxo-G) system in Pseudomonas putida?"
- "List five applications of machine learning algorithms in medical diagnosis."
- "Does the 3D structure of the genome remain stable during cell differentiation?"
- "What is the main biological function of the CRISPR-CAS9 genome editing system?"
- "Does dronedarone affect T3 and T4 levels?"
- "What is 2d 4d ratio in athletes."
- "What is the association between moon cycle and rupture risk of intracranial aneurysms?"
- "What is the role of brain natriuretic peptide in traumatic brain injury patients ?"
- "Which molecule is targeted by Daratumumab?"
- "Which mutation is associated with PLMS (periodic limb movements in sleep)?"
- "Which DNA repair system is involved in HNPCC?"
- "Mention the only available genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica"
- "What is the association between NT-proBNP and cognitive function?"
- "List functional roles of the FtsZ protein."
- "Intetumumab has been tested in clinical trials for treatment of which cancers?"
- "Is there any evidence of dysregulated long non coding RNAs and Alzheimer's disease?"
- "Which hormone receptor function is altered in patients with Donohue syndrome?"
- "Does triiodothyronine (T3) has cardiac angiogenic effects?"
- "Is the HRC Ser96Ala variant associated with sudden cardiac death in patients with dilated cardiomyopathy?"
- "Are BRAF mutations common in melanoma?"
- "Is it possible to determine the proteome of a formalin fixed and paraffin embedded (FFPE) tissue?"
- "What is known about type D personality trait in cancer patients?"
- "List available tools for genomic visualisation in comparative genomics"
- "Which species may be used for the biotechnological production of itaconic acid?"
- "Which types of cancer can be recognized and treated by the use of immunotherapy?"
- "What is the typical rash associated with gluten ?"
- "Which proteins constitute the methyl-directed mismatch repair system (MMR) in bacteria?"
- "Is aganglionic megacolon a feature of Down syndrome?"
- "Which is the vector of Louping ill virus?"
- "Does HuR protein regulate the splicing process?"
- "Is Titin the largest single protein molecule found in Nature?"
- "what is the role of MEF-2 in cardiomyocyte differentiation?"
- "Which are the main components of mTORC1?"
- "What is the the Menzerath-Altmann law?"
- "Which receptor(s) recognize lysosomal hydrolases in trans-Golgi network (TGN)?"
- "List the diseases that can be treated using Vedolizumab."
- "Can clonidine be used to reduce agitation in children."
- "Which value of nuchal translucency thickness is set as the threshold for high-risk for Down Syndrome?"
- "Does ventriculoperitoneal shunt improve normal pressure hydrocephalus?"
- "Does Serca2a bind PLN in the heart?"
- "What is the function of the spliceosome complex?"
- "Is there any role for long noncoding RNAs in adipogenesis?"
- "Which genes code for the alpha subunit of the DNA polymerase III in most Firmicutes?"
- "Is there any research that relates the function of Notch Signaling with Alzheimer Disease?"
- "Describe the known functions for the prothymosin alpha c-terminal peptide?"
- "Was modafinil tested for schizophrenia treatment?"
- "What is the role of the Ada O6-alkylguanine alkyltransferase in bacteria?"
- "List the neurotransmitters that are metabolized by MAOA."
- "What is the effect of enamel matrix derivative on pulp regeneration?"
- "Is depression associated with poor prognosis of brain tumor patients?"
- "Super-SILAC is a method used in quantitative proteomics. What is the super-SILAC mix?\n(SILAC: Stable Isotopic labelling by aminoacids in cell culture)"
- "What is an acceptable sequence coverage(depth) required for human whole-exome sequencing?"
- "To what extent does HPV vaccination reduce the risk for cervical cancer?"
- "Have germline variants been associated to colorectal cancer?"
- "Can Alzheimer's disease related miRNAs be detected in patients' blood?"
- "Which is the clinical meaning of the presence of delayed enhancement in patients with hypertrophic cardiomyopathy?"
- "What disease is mirtazapine predominantly used for?"
- "Is it possible to visualize subtahalamic nucleus by using transcranial ultrasound?"
- "Is cancer related to global DNA hypo or hypermethylation?"
- "Do thyroid hormone receptors change after brain injury?"
- "What is known about efficacy of the high dose intravenous ascorbate in the treatment of cancer patients?"
- "Alpha-spectrin and beta-spectrin subunits form parallel or antiparallel heterodimers?"
- "Is gastro esophageal reflux related to burning mouth syndrome?"
- "Which is the protein (antigen) targeted by anti-Vel antibodies in the Vel blood group?"
- "Which are the subtypes of Pfeiffer syndrome?"
- "Is thrombophilia related to increased risk of miscarriage?"
- "Intact macromolecular assemblies are analysed by advanced mass spectrometry. How large complexes (in molecular weight) have been studied?"
- "What is targeted by Palbociclib?"
- "Which peptide plays a pivotal role in human cystatin C fibrillization?"
- "What is ChiRP-seq (Chromatin Isolation by RNA Purification sequencing)?"
- "What is the use of MammaPrint and Oncotype DX?"
- "Does nifedipine inhibit L-type calcium channels?"
- "Is there any data to suggest that TRH (thyrotropin releasing hormone) administration can improve symptom severity of amyotrophic lateral sclerosis patients?"
- "How can DUF families be deciphered?"
- "Which genes does thyroid hormone receptor beta1 regulate in the heart?"
- "Can siRNA affect response to afatinib treatment?"
- "What is the gold standard treatment for Iatrogenic male incontinence?"
- "Which is the main CHEK2 genetic variant, thought to be involved in familial breast cancer?"
- "Is there an association between presenteeism and depression?"
- "Which hormone abnormalities are common in Williams syndrome"
- "What is the treatment of choice for gastric lymphoma?"
- "Which assays can be used for detecting DNA fragmentation resulting from programmed cell death (apoptosis)?"
- "Does triiodothyronine stimulate red blood cell sodium potassium pump?"
- "Which hormone concentrations are altered in patients with the Allan\u2013Herndon\u2013Dudley syndrome?"
- "Is selumetinib effective in thyroid cancer?"
- "Where in the cell does the proteins S100A4 and p53 interact ?"
- "What are the applications of a Dermaroller ?"
- "Are immune cells affected in Amyotrophic Lateral Sclerosis?"
- "Are OATP1B1 and OATP1B3 associated with bilirubin transport?"
- "What is the mechanism of action of eprotirome?"
- "What is the role of music therapy in coma patients."
- "Which is the causative agent of malaria?"
- "What is the major adverse effect of adriamycin(doxorubicin)?"
- "What is GDF10?"
- "Is thyroid hormone therapy indicated in patients with heart failure?"
- "Is there a mouse model for Fanconi anemia?"
- "Could Hyperthermic intraperitoneal chemotherapy (HIPEC) be effective for the treatment of recurrent ovarian cancer?"
- "Which is the most common editing modification in eukaryotic mRNA?"
- "Is Rac1 involved in cancer cell invasion?"
- "Which are the APOBEC3 protein family members able to inhibit Vif-deficient HIV-1 replication?"
- "Is the gene SLC6A2 associated with orthostatic intolerance?"
- "Other than protein coding potential, what features set apart long non-coding RNAs from protein coding genes?"
- "Is macitentan an ET agonist?"
- "Can we use platelet biomarkers to study Alzheimer's disease?"
- "Which genetic defects are observed in Prader-Willi syndrome?"
- "What is the most likely age of diagnosis of Crohn's disease (CD)?"
- "How does thyroid hormone affect insulin resistance in the heart?"
- "Which are the state-of-the-art computational tools for the prediction of gene fusion events?"
- "Is CHEK2 involved in cell cycle control?"
- "Describe mechanism of action of PLX3397 drug."
- "What disease is small bowel lymphoma commonly associated with"
- "Are the proteins Erbin (LAP2) and Merlin cooperating?"
- "Which molecule is targeted by a monoclonal antibody Secukinumab?"
- "Which calcium/calmodulin dependent protein phosphatase is involved in the activation of the family of NFAT transcription factors (Nuclear Factors of Activated T cells)?"
- "Is abdominal pain a common symptom in autism?"
- "Are cyclophilins ubiquitously expressed?"
- "Are adenylyl cyclases always transmembrane proteins?"
- "What histone trimethylation has been associated to RNA splicing?"
- "What was the purpose of the FANTOM4 project?"
- "Does low T3 negatively affect prognosis of patients after cardiac surgery?"
- "Which deficiency is the cause of restless leg syndrome"
- "List the results of mutated casein kinase 1 epsilon. "
- "Does neuroglobin has neuroprotective properties in the setting of traumatic brain injury?"
- "What gene test is recommended for clopidogrel?"
- "What is the role of eteplirsen in DMD patients?"
- "Describe clinical presentation of Parkinsonism with dementia of Guadeloupe syndrome."
- "Does the concentration of protein HIF-1\u03b1 increase after the administration of the cytoprotective prodrug\"amifostine\" (ethyol) ?"
- "Which diseases can Oncotype DX be used for?"
- "Which are the DNA (cytosine-5-)-methyltransferases inhibitors?"
- "Describe armoured brain syndrome."
- "Which are the main histone modifications associated with enhancers?"
- "What is the role of Thyrotropin Releasing Hormone in the treatment of comatose patients?"
- "Do Conserved noncoding elements act as enhancers?"
- "Can the iPS cell technology be used in Fanconi anemia therapy?"
- "Which drug is considered as the first line treatment of fibromyalgia?"
- "What are the signatures of aggressive periodontitis?"
- "With which complexes is the protein SUS1 associated?"
- "Can Preimplantation Genetic Diagnosis (PGD) be used for gender selection?"
- "What is the principle of ATAC (Assay for Transposase-Accessible Chromatin) technique?"
- "Which are the main NMD factors in Saccharomyces cerevisiae?"
- "Which histone marks are deposited by Set7?"
- "Has proteomics been used in the study of the dry eye syndrome?"
- "What is the indication for isradipine?"
- "List non-surgical treatment modalities that are included in the Stupp protocol."
- "Which genes are associated with Ehlers-Danlos syndrome type I/II?"
- "Which factors are considered in the ABCD2 score?"
- "Is Tuberous Sclerosis a genetic disease?"
- "Does TRIM37 gene mutation causes Mulibrey nanism?"
- "Have thyronamines effects on fat tissue?"
- "What is the genetic basis of progeria"
- "What type of DNA repair pathways is initiated by AlkA glycosylase?"
- "Is there any protein that undergoes both mono-ubiquitination and poly-ubiquitination?"
- "Which are the musculoskeletal manifestations of Marfan syndrome?"
- "What is the \"Proteomic ruler\"?"
- "What is the mechanism by which HIV-1-encoded Vif protein allows virus replication?"
- "Which proteins are the different isoforms of the p38 MAP kinase?"
- "Are pseudogenes enriched with housekeeping protein families?"
- "What is the mechanism of cementogenesis in pulp regeneration?"
- "What are the reported adverse effects of gabapentin used in children?"
- "What is the effect of ranolazine in diastolic heart failure?"
- "Elaborate on the potential efficacy of gemcitabine for the treatment of recurrent, platinum-resistant epithelial ovarian cancer."
- "Is olaparib effective for prostate cancer?"
- "How does Foxa transcription factor exhibits its pioneering function?"
- "Which are the 3 basic transcription factors that have been used for the direct reprogramming of fibroblasts into cardiomyocytes or cardiomyocyte like-cells?"
- "What is the name of Bruton's tyrosine kinase inhibitor that can be used for treatment of chronic lymphocytic leukemia?"
- "Is physical performance influenced by thyroid hormone metabolism?"
- "Do plant genomes contain CpG islands?"
- "Describe the isolation of transcription factor complexes by in vivo biotinylation tagging and direct binding to streptavidin beads, as applied for the case of the essential hematopoietic transcription factor GATA-1."
- "Are high-flow nasal cannulae effective for treatment of preterm infants?"
- "What are the molecular characteristics of the FAA (FANCA) cDNA?"
- "What are the skeletal muscle satellite cells?"
- "What is the role of neurogranin in Alzheimer's disease patients?"
- "Does triiodothyronine play a regulatory role in insulin secretion from pancreas?"
- "How many disulfide bridges has the protein hepcidin got?"
- "What is the association between GERD and gluten ?"
- "Which are the major intramolecular phosphorylation sites of human Chk2 involved in cell cycle control?"
- "Is the Histidine-Rich Calcium Binding protein (HRC) related to arrhythmias and cardiac disease?"
- "Which are the methods for in silico prediction of the origin of replication (ori) among bacteria?"
- "What is the use of emulsion PCR in Next Generation Sequencing?"
- "Can adult humans be induced to produce fetal hemoglobin?"
- "What is the role of thyroid hormone in Stem cell differentiation?"
- "Which receptors can be evaluated with the [18F]altanserin?"
- "Which diseases have been associated with the PTPN22 620W allele?"
- "Which extra thyroid tissues have thyrotropin (TSH) receptors?"
- "Which histone modifications distinguish between promoters and enhancers?"
- "Where is the metaxin complex localized?"
- "What are the major classes of retrotransposons active in the human genome?"
- "Which are the clinical characteristics of Diamond-Blackfan anemia?"
- "How can the expression of SerH3 immobilization antigen be regulated?"
- "Which factors play a role in promoter proximal pausing of RNA polymerase II?"
- "Which are the main clinical features of Fanconi anemia?"
- "Which is the receptor for the immunosuppressive drug cyclosporin A (CsA)?"
- "Which drugs may interfere thyroxine absorption?"
- "Is Turcot syndrome associated with glioblastoma?"
- "Which is the gene most commonly mutated in Tay-Sachs disease?"
- "In which types of DNA repair is the UvrAB complex involved?"
- "What is the localization of the protein encoded by the gene DNAJC11?"
- "Is Calcium/Calmodulin dependent protein kinase II (CaMKII) involved in cardiac arrhythmias and heart failure?"
- "What is the lay name of the treatment for CCSVI (chronic cerebro-spinal venous insufficiency) in multiple sclerosis."
- "Which hormone abnormalities are characteristic to Pendred syndrome?"
- "What is the mode of inheritance of long QT Jervell and Lange-Nielsen syndrome?"
- "List programs suitable for protein docking"
- "Which genes have been found mutated in Gray platelet syndrome patients?"
- "Does dasatinib promote or inhibit T-cell proliferation?"
- "Does SCRIB deregulation promote cancer?"
- "Is cardiac magnetic resonance imaging indicated in the pre-participation screening of athletes?"
- "Is imatinib an antidepressant drug?"
- "What is the function of the MTH1 enzyme in cancer cells?"
- "Are ultraconserved elements depleted among copy number variants (CNVs)?"
- "Is the microRNA 132 (miR-132) involved in brain pathologies?"
- "What is an approximate number of CTCF binding sites in the human genome?"
- "Does cucumber lower blood sugar in diabetics?"
- "Which mutations in the cardiac isoform of the ryanodine receptor (RyR2) have been found to be related to CPVT?"
- "Which population has a high frequency of the HLA-B*1502 allele?"
- "What are the observations regarding telomere integrity and function in Fanconi anemia?"
- "Are Notch mutations related to T-cell Acute Lymphoblastic Leukemia (T-ALL)?"
- "What is the role of the Tsix gene during X chromosome inactivation?"
- "Is the protein FAK (Focal Adhesion Kinase) phosphorylated?"
- "Which is the substrate of the haspin kinase during mitosis?"
- "Which are the most widely reported side-effects in the treatment of Crohn's disease?"
- "Are most driver gene mutations synonymous or non-synonymous?"
- "What is the advantage of neutral loss detection in phosphoproteomics?"
- "Does ghrelin play a role in ischemic stroke?"
- "What is the mechanism of drug-induced gingival overgrowth?"
- "Is LPS a microbial product?"
- "Which cyclin- dependent kinase inhibitor is regulated by Bmi-1?"
- "Which microRNAs are involved in exercise adaptation?"
- "Has field-programmable gate array (FPGA) technology been used to solve sequence alignment problems?"
- "List inhibtors targeting the mitochondrial permeability transition pore."
- "What is ceritinib?"
- "Which protein is found to be mutated in Friedreich's ataxia?"
- "Which is the process that Conserved noncoding elements mostly regulate?"
- "What is the main mechanism by which human papillomavirus proteins E6 and E7 contribute to cell transformation?"
- "List bacterial species identified in the iceman tissues."
- "Which properties of the mRNA does N6-methyladenosine (m6A) affect?"
- "What is the implication of histone lysine methylation in medulloblastoma?"
- "What is the Orco protein in mosquitos?"
- "List some ways to reverse Tau hyperphosphorylation in Tauopathies?"
- "What is the role of 5hmC (5 hydroxy-methyl-Cytocine) in differentiation?"
- "Which is the histone residue methylated by MLL1?"
- "What is CRISPRi?"
- "Which type of cells is affected in Amyotrophic Lateral Sclerosis?"
- "Is Achondroplasia associated with hearing loss?"
- "Is the JNK pathway activated during liver regeneration?"
- "Is STAT3 transcription factor regulated by mTORC1?"
- "How is mTORC1 involved in the regulation of heat stress?"
- "List components of the CRSP/Med complex."
- "Patients of which disease could be treated by utilizing knowledge obtained from experiments suppressing TDP-43 toxicity in yeast?"
- "Is calcium overload involved in the development of diabetic cardiomyopathy?"
- "What is the mechanism of viroid replication?"
- "Which mitochondrial genes are regulated by thyroid hormone?"
- "Mutation of which gene is associated with McLeod syndrome?"
- "Is RIP1 (RIP-1) part of the necrosome?"
- "Which is the molecular target of the immunosuppressant drug Rapamycin?"
- "Is the protein KCNQ2 associated with idiopathic epilepsy?"
- "PBT2 has been tested for which disorder?"
- "What is the basic secondary structure of the variable domains of a typical antibody?"
- "How does long-range epigenetic silencing (LRES) occur?"
- "What is the mode of inheritance of Acromicric dysplasia?"
- "Can RNAPolII function as an RNA-dependent RNA-polymerase?"
- "Which are the best treatment options to treat Helicobacter pylori?"
- "List sclerostin interaction partners."
- "Under which conditions does AMPK phosphorylate TSC2?"
- "What imaging modalities have been listed as method of choice to diagnose CSF leak?"
- "Which are currently available software tools for detecting rare codon clusters in coding sequences?"
- "How many tissue kallikrein genes are present in the human genome?"
- "Does the Oncotype DX test work with paraffin embedded tissues?"
- "Where does CTCF colocalize with cohesin?"
- "Name triad of Wernicke encephalopathy."
- "Is the PTPN22 gene a biomarker for Rheumatoid Arthritis?"
- "Is marijuana use associated with increased risk for stroke?"
- "How many and which are the different isoforms for the ryanodine receptor?"
- "Which compound is a specific inhibitor for Nox1 and Nox4?"
- "Which molecule is targeted by the drug Gevokizumab?"
- "Which protein phosphatases have been found to dephosphorylate phospholamban?"
- "What is the most prominent sequence consensus for the polyadenylation site?"
- "Does fibronectin constitute a serum biomarker for Duchenne muscular dystrophy?"
- "What colonoscopy findings have been reported in autism"
- "What is a disordered protein?"
- "What is the Drosophila melanogaster Groucho protein?"
- "Which enzyme is inhibited by Imetelstat?"
- "What is the catalytic mechanism of DNA (cytosine-5) methyltransferases? "
- "Are mutations in the STXBP1 gene associated with epilepsy?"
- "What is the mechanism of action of geldanamycin?"
- "Which is the most widely used anti-TNF drug?"
- "What is the association between number of pregnancies and rheumatoid arthritis"
- "Is mitofusin 2 a receptor for parkin?"
- "What are the main benefits of pharmacophore models?"
- "How Flaviviridae family of viruses infects vertebrates?"
- "What was the aim of the HAMLET clinical trial?"
- "Can we use prodrug amifostine to protect healthy cell during chemotherapy?"
- "Which is the main difference between Alu and B1 repeats?"
- "Is there a relationship between thyroid hormone altered metabolism and coronary artery disease?"
- "What is the frequency of mutations induced spontaneously through Ethylnitrosourea (ENU) mutagenesis?"
- "What is the molecular pathogenesis of Spinal Muscular Atrophy?"
- "Which drugs affect insulin resistance in obesity?"
- "Elaborate on the link between conserved noncoding elements (CNEs) and fractality."
- "Which is the primary protein component of Lewy bodies?"
- "Are microtubules marked by glutamylation?"
- "What is known about the Kub5-Hera/RPRD1B interactome?"
- "Willis-Ekbom disease is also known as?"
- "List two most common symptoms of Aagenaes syndrome."
- "Which are the side effects during tacrine administration in patients with Alzheimer's Disease?"
- "Is synapsin a phosphoprotein?"
- "Is Thalidomide currently a marketed drug?"
- "Which enzymes synthesize catecholamines in adrenal glands?"
- "How many cysteines have alpha-defensins?"
- "Could BRCA gene test used for breast and ovarian cancer risk?"
- "What is Desomorphine?"
- "Which two drugs are included in the Harvoni pill?"
- "What is the result of Mff overexpression in mitochondria?"
- "Has Glucose-6-phosphate dehydrogenase (G6PD) deficiency an X-linked inheritance?"
- "What is FFI, fatal familial insomnia"
- "Which mutated genes are associated with the Tourette's syndrome?"
- "Which enzyme is inhibited by niraparib?"
- "Which peak calling algorithm employs mixture model clustering under the hood?"
- "Data from which major epigenome projects are contained in the DeepBlue epigenomic data server?"
- "Which diseases that can be treated using the focused ultrasound thalamotomy."
- "Is the toxin produced by Clostridium botulinum always deadly?"
- "Is ocrelizumab effective for treatment of multiple sclerosis?"
- "Elaborate on the role of CARMEN in cardiac specification."
- "Is there a role of regorafenib for sarcoma treatment?"
- "Which drug was tested in the TEMSO Trial for multiple sclerosis?"
- "What is the mechanism of action of peginesatide?"
- "Describe mechanism of action of Eteplirsen?"
- "Which genes of the marmoset genome exhibit rapid sequence evolution?"
- "What is the importance of Janus Kinases in dermatology?"
- "What is the incidence of beta-thalassemia in Greek population?"
- "Is exon skipping correlated with exon circularization?"
- "What is the target of daratumumab?"
- "Which gene-defect causes the Vel-blood type?"
- "Is NADPH oxidase 5 expressed in rodents?"
- "List selective estrogen receptor degraders."
- "What is the role of ZNF335 in microcephaly?"
- "What molecule is targeted by Avelumab?"
- "What are the exonic splice enhancers?"
- "What are the birth defects associated with Zika-virus infection?"
- "What is Neisseria adhesin A?"
- "Which R package is used for the detection of chromosomal abnormalities from microarray data?"
- "List all the available databases of super enhancers"
- "Which are the consequences of the hyperphosphorylated tau in Alzheimers' Disease?"
- "Which is the \"bonding hormone\"?"
- "What causes Scurvy?"
- "Describe clinical presentation of Ambras syndrome."
- "Which diseases are involved in the severe cutaneous reactions (SCAR) spectrum?"
- "Which tool employs self organizing maps for analyzing synonymous codon usage?"
- "What is MINDY-1?"
- "What is the benserazide's mechanism of function when co-administered with L-DOPA in patients with Parkinson's Disease?"
- "What is regioneR?"
- "For what indications is thalidomide currently marketed?"
- "What are reactive metabolites?"
- "What is the \"wearing-off\" phenomenon in levodopa-treated patients with Parkinson's Disease?"
- "What are prions?"
- "Does Vitamin D induce autophagy?"
- "What is sQTLseekeR?"
- "What is Creutzfeldt-Jakob Disease (CJD)?"
- "Describe what is athelia syndrome?"
- "Is RASA2 involved in melanoma?"
- "What is BioCreative?"
- "What is Contrave prescribed for?"
- "Which is the chromosome area that the human gene coding for the dopamine transporter (DAT1) is located to?"
- "What type of mutation is causing the industrial melanism phenotype in peppered moths?"
- "What gene is mutated in Huntington's disease?"
- "Which software package is available for the analysis of conserved genomic loci?"
- "Mutation of which gene is implicated in the Christianson syndrome?"
- "What is Eteplirsen (Exondys 51)?"
- "What are the SINEUPs?"
- "What is trichotillomania?"
- "What is the mechanism of action of raxibacumab?"
- "What is the effect of CPEB3 binding to the CPE domain?"
- "Is SUMOylation a post-translational modification in eukaryotes?"
- "What is the Shelterin complex?"
- "What disease is the drug aducanumab targeting?"
- "Which human syndromes have been detected with Fluorescence in situ hybridization (FISH)?"
- "List symptoms of EAST syndrome."
- "When did the polio vaccine becomes available?"
- "Is Annexin V an apoptotic marker?"
- "Which are the lipid lowering drugs administered in patients with Coronary Artery Disease (CAD)?"
- "What are PD-1 inhibitors?"
- "Is the protein lefty an inhibitor of nodal?"
- "List drugs withdrawn from the market for cardiovascular adverse events."
- "Is Migalastat used for treatment of Fabry Disease?"
- "Where are Paneth cells located?"
- "Which are the types of viral meningitis?"
- "What are the different classes of orally administered drugs used to treat diabetes"
- "Which pipelines are used for analyzing data from ChIP-nexus experiments?"
- "What do statins do?"
- "Which cells secretes alpha defensin 5?"
- "Do statins cause diabetes?"
- "What is the effect of nocodazole cell treatment?"
- "What is Path2PPI?"
- "SPAG5 was implicated in which cancers?"
- "What are some of the effects of Zika Virus in infected individuals?"
- "What is the function of Oseltamivir when administered during flu?"
- "What is the composition of the gamma-secretase complex?"
- "List kinases that phosphorylates the protein Bora."
- "Are deletions of chromosomal regulatory boundaries associated with congenital disease?"
- "What is the role of the UBC9 enzyme in the protein sumoylation pathway?"
- "Can the Micro-C XL method achieve mononucleosome resolution?"
- "Can Diabetes be caused by a defect in a potassium chanel?"
- "Which fimA genotypes are associated with disease?"
- "Is rucaparib used for ovarian cancer treatment?"
- "What is the role of cohesins at the IFNG locus?"
- "Describe Wellens' Syndrome."
- "Which human disease is associated with mutated UBQLN2"
- "Which ApoE isoform is associated with hyperlipoproteinemia?"
- "Could hypophosphatemic rickets cause craniosynostosis?"
- "Is vortioxetine effective for treatment of depression?"
- "Which server is used for simulation of macromolecular diffusional association?"
- "Can beans induce apoptosis?"
- "What is the function of transthyretin in cerebrospinal fluid?"
- "Can you define iatrogenic disease?"
- "Where do the Schwann cells and melanocytes originate from?"
- "Please list 3 diseases associated with the PIEZO2 gene."
- "Is treatment resistant depression related to vitamin B9?"
- "Where is the protein slitrk1 localized?"
- "Describe clinical manifestation of the Harlequin syndrome."
- "What is the role of the constitutive photomorphogenesis 9 signalosome (CSN)?"
- "Is adalimumab effective for hidradenitis suppurativa?"
- "What is Legg-Calv\u00e9-Perthes Disease"
- "What is promoted by ERAP1-ERAP2 dimerization?"
- "What is plantar fasciitis"
- "Which is the enzymatic activity of OTULIN?"
- "List diseases that could be targeted by disaggregases?"
- "Can NEECHAM Confusion Scale be used for evaluation of postoperative delirium?"
- "What is adhesive capsulitis"
- "Describe the applicability of Semantic MediaWiki in the case of FANTOM5"
- "Is there an association between Muenke Syndrome and FGFR3 gene mutation?"
- "Which R package is used for visualization of linear and circular karyotypes?"
- "Has small pox been eradicated from the world?"
- "Where is Akkermansia muciniphila found?"
- "Is there alternative polyadenylation during zebrafish development?"
- "Which NADPH oxidase family member requires interaction with NOXO1 for function?"
- "Are alterations in ultraconserved elements implicated in breast cancer?"
- "What is the mechanism of action of Osimertinib?"
- "What is Bartter syndrome?"
- "Is there any tool that facilitates the functional analysis of cis-regulatory regions in zebrafish?"
- "List RNA modifications databases"
- "Please list the 3 findings in HELLP syndrome."
- "Which mutated gene is associated with Waardenburg and Tietz syndromes?"
- "List the three most abundant bacterial phyla present in mouse feces."
- "What gene is mutated in Sickle Cell Anemia?"
- "What is the function of the Indian hedgehog protein in chondrocytes?"
- "What is the function of R-spondin 1 and noggin in non-damaged gallbladders?"
- "List the classical triad of symptoms of the Melkersson\u2013Rosenthal syndrome."
- "Which disease is treated with taliglucerase alfa?"
- "What is formin associated with in the snail?"
- "What is the major difference between eucaryotes and procaryotes?"
- "What is the HSP70-HSP110 disaggregase machinery?"
- "Has whole exome sequencing been performed in Alzheimer patients?"
- "Which is the genome browser database for DNA shape annotations?"
- "Is Stat4 a transcription factor?"
- "Have the promoter regions of the genes implicated in Rett Syndrome been characterized with CAGE?"
- "Has \"RNA interference\" been awarded Nobel prize?"
- "Is there any role for Pds5b in cohesion establishment?"
- "Which factors are considered in the FUNC score for intracerebral hemorrhage?"
- "Where is the respirasome located?"
- "Describe the usefulness of MiRduplexSVM."
- "What genes are drug targets for Fibrodysplasia Ossificans Progressiva (FOP)?"
- "What kind of analyses are performed with the software tool \"unipept\""
- "What is the role of gamma-secreatase complex in Alzheimer's Disease?"
- "Which syndromes are associated with heterochromia iridum?"
- "What is the target of tanezumab?"
- "Could plasmepsins be used as targets for developing anti-malaria drugs?"
- "What is MRSA?"
- "List peptide fragmentations methods in mass spectrometry"
- "Is avanafil indicated for treatment of erectile dysfunction?"
- "What is \"Epitranscriptome analysis\"?"
- "Which infection can be prevented with Dapivirine?"
- "What is Bexsero?"
- "Is there a role for gamma knife in treatment of Obsessive-Compulsive Disorder?"
- "What is the mechanism of action of the biguanide class of diabetes drugs?"
- "Where is the proteasome located?"
- "What is clinical presentation of the Gardner-Diamond syndrome?"
- "Where can you find the annulus of Zinn?"
- "What is the indication for SLCO1B1 genotyping?"
- "List available circular RNA prediction tools."
- "Which disease is treated with Nusinersen?"
- "Which disease the London mutation involved in?"
- "Define lncRNA."
- "How many microorganisms are present in human normal gut?"
- "What is the role of 3,4-diaminobenzoic acid derivatives in the immune system?"
- "Can NADPH oxidase be inhibited by apocynin and diphenylene iodonium?"
- "Viliuisk encephalomyelitis is diagnosed in which geographical area?"
- "What are Septins?"
- "What is the drug target for Simtuzumab?"
- "What is Dravet syndrome?"
- "What makes telomerase a good drug target?"
- "What is DENdb?"
- "List scales that are used for scoring of patients with spinal metastasis?"
- "Does NADPH oxidase 5 require any subunit for function?"
- "What are the side effects during statins administration in patients with atherosclerosis?"
- "Entresto is composed of which two drugs?"
- "What is the doRiNA database?"
- "Is NSD-1015 an inhibitor of Aromatic L-Amino Acid Decarboxylase?"
- "Is pseudouridine a RNA modification?"
- "What does the human ABCC gene product do?"
- "What is the connection between furin and hepcidin?"
- "Which cells express CIDEC protein in humans?"
- "Which is the relation between coffee consumption and stroke risk?"
- "What is the purpose of the Orpington Prognostic Scale?"
- "Do IEG create a ripple effect of transcription?"
- "Which R package is used for the analysis of genome-wide DNA methylation profiles?"
- "Do T-Cells regulate neuropathic pain?"
- "What is the incidence of new cases of X-linked adrenoleukodystrophy (ALD) in Australian and New Zealand in the late 1990's?"
- "Can telomere length shortening be reversed by telomerase?"
- "Is ABCE1 involved in ribosomal recycling?"
- "What are clinical features of the de Morsier syndrome?"
- "Does oculocutaneous albinism show an autosomal recessive inheritance?"
- "Which is the largest metabolic gene cluster in yeast?"
- "What is the applicability of the MCAST algorithm?"
- "Which ApoE isoform is associated with atherosclerosis and Alzheimer's disease?"
- "Are Ultra-conserved elements (UCEs) enriched in segmental duplications?"
- "What organism causes woolsorter's disease"
- "Which annotated database of A-to-I RNA editing is available?"
- "Do normal cells express the protein TERT?"
- "Which protein complexes recognize centromeric (CEN) DNA in yeast?"
- "Is there any involvement of the long non-coding RNA Gomafu in schizophrenia?"
- "Is butterfly rash a symptom of Systemic lupus erythematosus?"
- "What is the function of yeast Clr4 on chromatin?"
- "What is the role of LIMT lncRNA?"
- "Is infertility characteristic of individuals with Fanconi anemia?"
- "What are Kupffer cells and what is their role?"
- "What is known about saponins in crops and human consumption?"
- "Is golimumab effective for ulcerative colitis?"
- "What is the role of histone variant H2A.W?"
- "Which are the main brain dysfunctions caused by hyperbilirubinemia?"
- "Does mTOR regulate the translation of MAPKAPK2?"
- "What chromosome is affected in Turner's syndrome?"
- "What is the aim of the TRAP assay?"
- "Describe clinical applications of the PIM2 scoring system."
- "Do histone variant mH2A (macro-H2A) levels decrease upon differentiation?"
- "Which disease is associated with mutations in SLC40A1 gene?"
- "Could divalent metal transporter 1 deficiency lead to anemia?"
- "Does the hERG gene code for a protein which is part of a sodium channel?"
- "Is lenvatinib effective for renal cell carcinoma?"
- "Which proteins form part of the NRD complex in S. cerevisiae?"
- "Which R / bioconductor package is used for performing SNP enrichment analysis?"
- "Does HuR bind to the untranslated regions (UTRs) of mRNAs?"
- "Describe Exploding head syndrome."
- "Is H4K20 methylation associated with DNA replication?"
- "Describe crowned dens syndrome."
- "Does CRISPR inversion of CTCF sites alter genome topology?"
- "How are looped genes identified in yest?"
- "Which are the causes of the Koebner phenomenon?"
- "Is there a role of proton beam therapy in medulloblastoma treatment?"
- "What is the function of the DGAT1 gene product?"
- "Which histone mutation is associated with gliomas?"
- "Are there canonical marks of active chromatin in developmentally regulated genes?"
- "What is the purpose of HaploReg v4?"
- "Which are the typical symptoms of M\u00e9ni\u00e8re's disease?"
- "What tissue is most affected in Ehlers-Danlos syndromes?"
- "What is Mondor's disease?"
- "List metalloenzyme inhibitors."
- "How are immediate early genes (IEG) defined?"
- "Which proteins remove H2A.Z in the yeast Saccharomyces cerevisiae?"
- "Which library is used for fixed-length approximate string matching?"
- "Are there methods for generating highly multiplexed ChIP-seq libraries?"
- "Is Doxorubicin cardiotoxic?"
- "Which diseases are associated with Primary intestinal lymphangiectasia (PIL)?"
- "Is the mouse Sry gene locus free of repetitive sequences?"
- "Is Meis1 implicated in microphthalmia?"
- "Can Pentraxin 3 predict outcomes of sepsis?"
- "Which polymerase transcribes pri-miRNAs?"
- "Which mutated enzyme is responsible for oculocutaneous 1 (OCA1)-type albinism?"
- "Please list 2 treatments for a torn rotator cuff"
- "What is the role of Laser Interstitial Thermal Therapy in glioma treatment?"
- "Which protein mediates the replacement of H2A by H2A.Z in the yeast Saccharomyces cerevisiae?"
- "Which are the key players on radial glial specification to ependymal cells?"
- "Is ocular melanosis a risk factor for uveal melanoma?"
- "What is known about telomere length shortening and stress?"
- "What fruit causes Jamaican vomiting sickness?"
- "Which gene is mutated in the Karak syndrome?"
- "What is LedPred?"
- "Is siltuximab effective for Castleman disease?"
- "What are Degrons?"
- "Which disease is associated with mutated Sox2?"
- "Is the enzyme EPRS phosphorylated?"
- "Which disease the skin condition Necrobiosis lipoidica diabeticorum is associated to?"
- "What is the role of Lysine 2-hydroxyisobutyrylation?"
- "List diseases associated with the Dopamine Receptor D4 (DRD4)."
- "Which bacteria cause diphtheria?"
- "What is the function of calcium-sensing receptor (CaSR)?"
- "List drug that were evaluated in the CHAMP trial for migraine."
- "What is the role of IL-18BP?"
- "Which protein mediates gene loop formation in the yeast S. cerevisiae?"
- "Which two drugs were compared in the ARISTOTLE Trial?"
- "What is REVIGO?"
- "What is the mechanism of action of onartuzumab?"
- "Is there a relationship between B cells and Multiple Sclerosis?"
- "Which virus type causes Molluscum contagiosum?"
- "Which disease(s) are caused by HEX A deficiency?"
- "What is Beh\u00e7et's disease"
- "Does Yersinia pestis causes a respiratory infection?"
- "List 3 indications for Bupropion"
- "What is the function of BAX"
- "What is the link between Ctf4 and Chl1 in cohesion establishment?"
- "How is primary intestinal lymphangiectasia (PIL) caused?"
- "What are congenital disorders of glycosylation?"
- "Which are the additions of the JASPAR 2016 open-access database of transcription factor binding profiles?"
- "What is the function of the protein tafazzin?"
- "What are assassin bugs?"
- "Are the genes for marneral biosynthesis scattered in the genome of A. thaliana?"
- "Is Dupilumab used for treatment of atopic dermatitis?"
- "Where is base J found in the genome of Leishmania tarentolae?"
- "Which tool is available for predicting regulatory interactions from ChIP-seq data?"
- "Where are the unipolar brush cells localized?"
- "Which driver mutations have been identified for Diffuse Intrinsic Pontine Glioma (DIPG)?"
- "Does Jarid2 play a role in early embryo development?"
- "Is PUVA therapy indicated for eczema treatment?"
- "What is DECKO?"
- "List genes associated with hypolipidemia."
- "What is the enzymatic activity of PARL?"
- "Do brown fat cells produce heat?"
- "What is a mimotope vaccine?"
- "Describe clinical manifestation of the Mal de debarquement syndrome."
- "Is Melioidosis caused by the bacterium\u00a0Burkholderia pseudomallei?"
- "What is the mechanism of action of verubecestat?"
- "How are triple negative gliomas characterized?"
- "What is ectopia lentis?"
- "Can glyburide reduce cerebral edema?"
- "What is the function of gasdermin D?"
- "What is TOPAZ1?"
- "Which are the symptoms of glucose-6-phosphate dehydrogenase (G6PD) deficiency?"
- "Has the gorilla genome been determined?"
- "Is vemurafenib used for thyroid cancer?"
- "Are mutations in the C9orf72 gene associated with macular degeneration?"
- "What is the Genome 10K Project?"
- "Which gene controls the expression of GATA-1 isoforms?"
- "What is MIRA-seq?"
- "How does Ssu72 mediate gene looping?"
- "Is the number of described human nuclear mutations less than 50000?"
- "What is the role of peptide aptamers?"
- "Which are the clinical symptoms of left ventricular noncompaction?"
- "What is the Glasgow Coma score?"
- "Andexanet Alfa is an antidote of which clotting factor inhibitors?"
- "Which is the main cause of the Patau syndrome?"
- "Which is the main abnormality that arises with Sox9 locus duplication?"
- "Is Musclin a secretory peptide?"
- "What tissue is commonly affected in Marfan's syndrome"
- "To which disease does the loss of CD28 expression by liver-infiltrating T cells contribute?"
- "Are cutaneous porphyrias inherited with a recessive pattern?"
- "Which disease is treated with ZMapp?"
- "Can methylenetetrahydrofolate reductase (MTHFR) gene mutations cause homocystinuria?"
- "What happens to H2AX upon DNA bouble strand breaks?"
- "Can valproic acid prolong survival of glioblastoma patients?"
- "What is the effect of the direct interaction of Ikaros and Foxp1 in B-lymphocytes?"
- "Which syndrome is caused by deletion of Pds5b in mice?"
- "What is the inheritance of Barth syndrome?"
- "Is Cryptococcus neoformans a frequent cause of isolated skin infections in immunocompromised individuals"
- "What is the mechanism of action of Pictilisib?"
- "What are sirtuins?"
- "Which miRNA is targeted by SRY/Sox9?"
- "Which technique led to the elucidation of the role of HOXD10 in regulating lymphatic endothelial responses to VEGF-C?"
- "Is Obeticholic Acid used for treatment of Primary Biliary Cholangitis?"
- "What alternate indication has Vanoxerine been repositioned for?"
- "What is the applicability of the No Promoter Left Behind method?"
- "Which mutated genes are associated with isolated ectopia lentis?"
- "Does the word ovine refers to goats?"
- "Does GATA-1 regulate ribosomal protein genes?"
- "Which gene mutations cause the Marfan syndrome?"
- "What is the indication of ARCALYST?"
- "What is ChIPpeakAnno?"
- "Signaling of which pathways is inhibited by Dupilumab?"
- "Does the TOP2B/TOP2A expression ratio affect the response to AML chemotherapy?"
- "List the three main structures of the cytoskeleton."
- "What is the genus for the common European honey bee?"
- "Where is the TAZ (G4.5) is located in humans?"
- "What do nerve-associated peripheral glial progenitors give rise to?"
- "How many topological associated domains are contained in the human Hox cluster?"
- "Is Lennox-Gastaut Syndrome usually diagnosed in older adults?"
- "Which treatment methods were compared in the EXCEL Trial?"
- "Describe ATR-16 syndrome."
- "What is the results of inactivated ANGPLT3?"
- "What percentage of rheumatoid arthritis patients are responsive to anti-TNF therapy?"
- "Which disease is treated with semaglutide?"
- "What condition is usually represented by the acronym SUDEP?"
- "Which proteins does the yeast Cleavage and Polyadenylation Complex contain?"
- "Which disease can be categorized using the Koos grading system?"
- "What is the inheritance of the glucose-6-phosphate dehydrogenase (G6PD) deficiency?"
- "Which deep learning-based algorithms are used for enhancer prediction?"
- "Is Beta-Thalassemia is associated with a mutation or deletion of the gene that codes for alpha globin?"
- "Is diphosphatidylglycerol (cardiolipin) a phospholipid of the mitochondrial membranes?"
- "Have studies shown that there is no link between DNA methylation patterns and Post Traumatic Stress Disorder?"
- "Is POLD3 essential for mouse development?"
- "What is the mechanism of action of Romosozumab?"
- "Symptoms of which disorder are evaluated with the Davidson Trauma Scale?"
- "What is the function of the Mis18 protein?"
- "Are hepadnaviral minichromosomes free of nucleosomes?"
- "Is Cri Du Chat associated with an expansion of a repeat with in the gene found on chromosome 5?"
- "What are the roles of Smyd3 in zebrafish?"
- "Which enzyme is inhibited by ribociclib?"
- "Which histone mutations have been associated with pediatric gliomas?"
- "Is it feasible to obtain DNA read lengths that exceed 30 Kb?"
- "Is osteocrin expressed exclusively in the bone?"
- "What is Achondroplasia?"
- "What is the indication for Mirabegron?"
- "What is the cause of Tardive dyskinesia?"
- "Are alterations in ultraconserved elements associated with colorectal adenocarcinoma?"
- "What is PANTHER-PSEP?"
- "What is MPE-seq?"
- "Describe the mechanism of action of Bezlotoxumab?"
- "Is apremilast effective for psoriasis?"
- "Is skin color affected by variations of the SLC24A5 gene?"
- "How are Arboviruses transmitted?"
- "Which bacterium has the smallest genome in base pairs yet found?"
- "Which are the triad symptoms of pheochromocytoma?"
- "List the types of the Cardiorenal syndrome (CRS) according to the five-part classification system."
- "What is a miR?"
- "Do circRNAs remain untranslated?"
- "What is the biological function of the SRY circular RNA (circRNA)?"
- "What is Uhl's anomaly?"
- "Is autophagy the process where bacteria ingest viral particles?"
- "Can aspirin be used in cancer prevention?"
- "Which are the components of the pre-replication complex (pre-RC) in eukaryotes?"
- "What is the inheritance of hypophosphatemic rickets?"
- "Which mushroom is poisonous, Amanita phalloides or Agaricus Bisporus"
- "Which is the most common gene signature in Rheumatoid Arthritis patients?"
- "Which NGS alignment software implement the Burrows-Wheeler Transform?"
- "Is intraoperative radiotherapy used for treatment of glioblastoma?"
- "Which server is used for generating modes of pseudo components of DNA, RNA and protein sequences?"
- "What is the link between TB (Turbeculosis) infection and TNFa inhibition?"
- "Which class of genes are mutated in Diamond Blackfan Anemia patients?"
- "List the human acrocentric chromosomes that are involved in Robertsonian translocation."
- "Is tirilazad effective for treatment of aneurysmal subarachnoid haemorrhage?"
- "Which protein is the main marker of Cajal bodies?"
- "Which mutated gene causes the Ch\u00e9diak\u2013Higashi Syndrome?"
- "The pathogen Fusarium graminearum affects what type of plant species?"
- "List viral vectors used in gene therapy."
- "Is dexamethasone recommended for treatment of intracerebral hemorrhage?"
- "What happens upon disruption of a TAD boundary?"
- "List the classical symptoms of the Moschcowitz syndrome (Thrombotic thrombocytopenic purpura)."
- "Is airplane stroke syndrome a common disease."
- "Which R / bioconductor package is used for enrichment analysis of genomic regions?"
- "Which is the major RNA editing enzyme in Drosophila melanogaster?"
- "What is the CEGA catalog?"
- "Which protein is associated with hyperemesis gravidarum during pregrancy?"
- "Is hydroxyurea usually used to treated infectious disease?"
- "What is magnetoreception?"
- "Can acupuncture cause spinal epidural hematoma?"
- "Is edema a symptom of nephrotic syndrome?"
- "Angelman syndrome is associated with deletion of a part of Chromosome 15 but if the deletion occurs in the paternally inherited chromosome 15, what is the disease?"
- "What is the phenotype of people carrying mutations in the gene PRDM12?"
- "Is there an association between Histone H3.3 mutations and glioma?"
- "Which cellular function is associated with transcription factors forkhead 1 and 2 (Fkh1 and Fkh2)?"
- "What is the role of the Ctf4-interacting-peptide or CIP-box?"
- "What type of genome, (RNA or DNA, double stranded single stranded) is found in the the virus that causes blue tongue disease?"
- "What is a \"chemobrain\"?"
- "Borden classification is used for which disease?"
- "Which effects create neighborhoods of transcriptional regulation in eukaryotes?"
- "Is Pfh1 a component of the replisome?"
- "What is the function of mTOR?"
- "What is the indication for valbenazine?"
- "List features of the Kaufman Oculocerebrofacial Syndrome."
- "What is the role of DNA Repair Cofactors ATMIN and NBS1?"
- "The MMR vaccine protects against what 3 viruses?"
- "List cardinal features of the Triple A syndrome."
- "Describe the applicability of Basset in the context of deep learning"
- "Does the Abelson-related gene (ARG) gene encode for a serine kinase?"
- "What organism causes tularemia?"
- "Is Prochlorococcus the most abundant photosynthetic organism?"
- "List 3 features of IRVAN syndrome."
- "Which are the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) inhibitors that are FDA approved?"
- "Is dupilumab an antibody targeting the IL-1 receptor?"
- "List active ingredients of the Stribild polypill."
- "List clinical features of the IMAGe syndrome."
- "Which gene mutations are predictive of response to anti-TNF therapy in Rheumatoid Arthritis patients?"
- "Which method is used for prediction of novel microRNA genes in cancer-associated genomic regions?"
- "Does the histone chaperone ASF1 interact with histones H1/H2?"
- "Is Hepatic mesenchymal hamartoma usually a malignant tumor?"
- "List clinical features of EEM syndrome."
- "How many times is CLAST faster than BLAST?"
- "Which are the most common methods for circular RNA detection from RNASeq?"
- "From which cell type is leptin secreted?"
- "Which tool is used for the identification of recurrent variants in noncoding regions?"
- "What body parts are also known as phalanges?"
- "Are selenium supplements recommended for prostate cancer prevention?"
- "Which disease is treated with lucinactant?"
- "Which proteins control the degradation of cryptic unstable transcripts (CUTs) in yeast?"
- "Is there any involvement of L1 retrotransposition in the Rett syndrome?"
- "Is Downs syndrome associated with decreased risk of leukemia?"
- "Which enzyme is inhibited by ixazomib?"
- "Does PCSK9 (Proprotein convertase subtilisin/kexin type 9) binds with HDL-receptor (HDL-R)?"
- "Hy's law measures failure for what organ?"
- "Is apremilast effective for psoriatic arthritis?"
- "Is there any role of TBR1 in autism?"
- "What is the role of the MCM2-7 complex?"
- "In which fields of DNA sequencing are Bloom filters applied?"
- "Which 2 medications are included in the Qsymia pill?"
- "Is sonidegib effective for basal cell carcinoma?"
- "Which R package could be used for the identification of pediatric brain tumors?"
- "Describe the usefulness of CAMUR in The Cancer Genome Atlas (TCGA)"
- "Which markers are screened with the triple test for the detection of syndromes in fetus?"
- "What is the role of TAD protein domain?"
- "What is the function of lncRNA?"
- "What is the function of the exosome?"
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